SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wwm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5wwm RRNA BIOGENESIS
PROTEIN RRP5
(Saccharomyces
cerevisiae) 		5 / 12 LEU A1502
ALA A1498
GLU A1499
VAL A1536
ARG A1539
 None
 1.30A 1s9pB-5wwmA:
undetectable		 1s9pB-5wwmA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_B_BEZB261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 5wwm RRNA BIOGENESIS
PROTEIN RRP5
(Saccharomyces
cerevisiae) 		4 / 8 ASN A1525
ILE A1556
PHE A1537
TYR A1557
 None
 1.41A 3ccfB-5wwmA:
undetectable		 3ccfB-5wwmA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_A_LURA201_1
(TRANSTHYRETIN)		 5wwm RRNA BIOGENESIS
PROTEIN RRP5
(Saccharomyces
cerevisiae) 		3 / 3 LYS A1631
LEU A1627
ALA A1630
 None
 0.68A 4iizA-5wwmA:
undetectable		 4iizA-5wwmA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 5wwm RRNA BIOGENESIS
PROTEIN RRP5
(Saccharomyces
cerevisiae) 		3 / 3 TRP A1478
MET A1479
ASN A1480
 None
 0.97A 5uc1B-5wwmA:
undetectable		 5uc1B-5wwmA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 5wwm RRNA BIOGENESIS
PROTEIN RRP5
(Saccharomyces
cerevisiae) 		3 / 3 TRP A1478
MET A1479
ASN A1480
 None
 0.90A 5uc1A-5wwmA:
undetectable		 5uc1A-5wwmA:
11.42