SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wx8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGQ_A_PCFA1275_0
(WNT INHIBITORY
FACTOR 1)		 5wx8 IMMEDIATE-EARLY
PROTEIN 2
(Human
betaherpesvirus
6A) 		5 / 12 ILE A1466
ILE A1367
ILE A1354
MET A1356
PHE A1358
 None
 1.07A 2ygqA-5wx8A:
undetectable		 2ygqA-5wx8A:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 5wx8 IMMEDIATE-EARLY
PROTEIN 2
(Human
betaherpesvirus
6A) 		3 / 3 ASP A1400
LYS A1399
ASP A1398
 None
 0.76A 4a7tA-5wx8A:
undetectable		 4a7tA-5wx8A:
21.16