SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wxm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 5wxm U3 SMALL NUCLEOLAR
RIBONUCLEOPROTEIN
PROTEIN IMP3
(Saccharomyces
cerevisiae) 		3 / 3 ARG A  55
ARG A  28
ARG A  56
 None
 0.89A 1l7fA-5wxmA:
undetectable		 1l7fA-5wxmA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 5wxm U3 SMALL NUCLEOLAR
RIBONUCLEOPROTEIN
PROTEIN IMP3
(Saccharomyces
cerevisiae) 		3 / 3 ARG A  55
ARG A  28
ARG A  56
 None
 0.88A 1l7hA-5wxmA:
undetectable		 1l7hA-5wxmA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1F_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 5wxm U3 SMALL NUCLEOLAR
RIBONUCLEOPROTEIN
PROTEIN IMP3
U3 SMALL NUCLEOLAR
RNA-ASSOCIATED
PROTEIN MPP10
(Saccharomyces
cerevisiae) 		5 / 12 ASP A  53
LEU U 444
LEU A  82
MET A  85
ILE A  54
 None
 1.04A 4x1fA-5wxmA:
undetectable		 4x1fA-5wxmA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1G_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 5wxm U3 SMALL NUCLEOLAR
RIBONUCLEOPROTEIN
PROTEIN IMP3
U3 SMALL NUCLEOLAR
RNA-ASSOCIATED
PROTEIN MPP10
(Saccharomyces
cerevisiae) 		5 / 12 ASP A  53
LEU U 444
LEU A  82
MET A  85
ILE A  54
 None
 1.08A 4x1gA-5wxmA:
undetectable		 4x1gA-5wxmA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_C_FK5C201_1
(FK506-BINDING
PROTEIN 1)		 5wxm U3 SMALL NUCLEOLAR
RIBONUCLEOPROTEIN
PROTEIN IMP3
U3 SMALL NUCLEOLAR
RNA-ASSOCIATED
PROTEIN MPP10
(Saccharomyces
cerevisiae) 		5 / 10 ASP A  53
ARG A  56
VAL A 103
ILE A 106
LEU U 448
 None
 1.28A 5hw8C-5wxmA:
undetectable
5hw8H-5wxmA:
undetectable		 5hw8C-5wxmA:
19.02
5hw8H-5wxmA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 5wxm U3 SMALL NUCLEOLAR
RIBONUCLEOPROTEIN
PROTEIN IMP3
(Saccharomyces
cerevisiae) 		4 / 8 LEU A  82
VAL A  87
VAL A 101
ILE A  50
 None
 0.70A 5y9mX-5wxmA:
undetectable		 5y9mX-5wxmA:
20.25