SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wxu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 5wxu 11S GLOBULIN
(Wrightia
tinctoria) 		5 / 12 ILE A  80
ILE A 388
ASN A 349
TYR A 394
LEU A 331
 None
 1.23A 1fm4A-5wxuA:
undetectable		 1fm4A-5wxuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BL9_A_CP6A1240_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5wxu 11S GLOBULIN
(Wrightia
tinctoria) 		5 / 12 ILE A 105
ALA A 333
LEU A 326
ILE A 295
ILE A 104
 None
None
None
FLC  A 503 (-3.9A)
None
 1.11A 2bl9A-5wxuA:
undetectable		 2bl9A-5wxuA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5wxu 11S GLOBULIN
(Wrightia
tinctoria) 		3 / 3 LYS A 409
ASP A 306
ASN A 334
 None
 1.10A 2bm9A-5wxuA:
undetectable		 2bm9A-5wxuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WM3_A_NFLA1301_1
(NMRA-LIKE FAMILY
DOMAIN CONTAINING
PROTEIN 1)		 5wxu 11S GLOBULIN
(Wrightia
tinctoria) 		4 / 6 LEU A 405
THR A 407
PHE A 386
LEU A 385
 None
 1.06A 2wm3A-5wxuA:
undetectable		 2wm3A-5wxuA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		 5wxu 11S GLOBULIN
(Wrightia
tinctoria) 		4 / 6 ASN A  99
ALA A 100
HIS A 184
ASP A  81
 None
None
PO4  A 501 (-3.9A)
None
 1.35A 3aruA-5wxuA:
undetectable		 3aruA-5wxuA:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJ8_C_SPMC500_1
(DIAMINE
ACETYLTRANSFERASE 1)		 5wxu 11S GLOBULIN
(Wrightia
tinctoria) 		4 / 6 LEU A 385
ASP A  81
LEU A 186
TRP A  68
 None
 1.21A 3bj8C-5wxuA:
undetectable
3bj8D-5wxuA:
undetectable		 3bj8C-5wxuA:
19.19
3bj8D-5wxuA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FZG_A_SAMA300_0
(16S RRNA METHYLASE)		 5wxu 11S GLOBULIN
(Wrightia
tinctoria) 		5 / 12 GLY A 363
GLY A 399
LEU A 338
VAL A 358
GLN A 384
 None
 1.23A 3fzgA-5wxuA:
undetectable		 3fzgA-5wxuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_2
(PROTEASE)		 5wxu 11S GLOBULIN
(Wrightia
tinctoria) 		5 / 9 LEU A 162
GLY A 111
ILE A 112
ILE A 295
ILE A 160
 None
None
None
FLC  A 503 (-3.9A)
None
 1.11A 3s56B-5wxuA:
undetectable		 3s56B-5wxuA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_A_T1CA392_1
(TETX2 PROTEIN)		 5wxu 11S GLOBULIN
(Wrightia
tinctoria) 		5 / 11 GLN A 108
GLY A 109
ALA A  62
GLY A  63
GLU A  61
 None
 1.16A 4a6nA-5wxuA:
undetectable		 4a6nA-5wxuA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5wxu 11S GLOBULIN
(Wrightia
tinctoria) 		5 / 12 ILE A  80
ILE A 388
ASN A 349
TYR A 394
LEU A 331
 None
 1.15A 4a84A-5wxuA:
undetectable		 4a84A-5wxuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_A_BEZA1000_0
(BENZOATE-COENZYME A
LIGASE)		 5wxu 11S GLOBULIN
(Wrightia
tinctoria) 		4 / 7 ALA A 170
ILE A 112
GLY A 111
ILE A 154
 None
 0.66A 4eatA-5wxuA:
undetectable		 4eatA-5wxuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5wxu 11S GLOBULIN
(Wrightia
tinctoria) 		5 / 9 GLU A  66
LEU A  75
VAL A 182
LEU A 181
ILE A 183
 None
 1.33A 4r38C-5wxuA:
undetectable		 4r38C-5wxuA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_2
(HIV-1 PROTEASE)		 5wxu 11S GLOBULIN
(Wrightia
tinctoria) 		5 / 12 LEU A 162
GLY A 111
ILE A 112
ILE A 295
ILE A 160
 None
None
None
FLC  A 503 (-3.9A)
None
 0.86A 5e5kB-5wxuA:
undetectable		 5e5kB-5wxuA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGZ_A_SPRA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5wxu 11S GLOBULIN
(Wrightia
tinctoria) 		5 / 9 LEU A 181
ILE A 355
ILE A  67
VAL A  86
GLU A  53
 None
 1.41A 5igzA-5wxuA:
undetectable		 5igzA-5wxuA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5wxu 11S GLOBULIN
(Wrightia
tinctoria) 		3 / 3 VAL A 179
VAL A 107
GLN A 382
 None
 0.62A 5qgjA-5wxuA:
undetectable		 5qgjA-5wxuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5wxu 11S GLOBULIN
(Wrightia
tinctoria) 		3 / 3 VAL A 179
VAL A 107
GLN A 382
 None
 0.65A 5qgmA-5wxuA:
undetectable		 5qgmA-5wxuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5wxu 11S GLOBULIN
(Wrightia
tinctoria) 		3 / 3 VAL A 179
VAL A 107
GLN A 382
 None
 0.59A 5qgyA-5wxuA:
undetectable		 5qgyA-5wxuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5wxu 11S GLOBULIN
(Wrightia
tinctoria) 		3 / 3 VAL A 179
VAL A 107
GLN A 382
 None
 0.59A 5qgzA-5wxuA:
undetectable		 5qgzA-5wxuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5wxu 11S GLOBULIN
(Wrightia
tinctoria) 		3 / 3 VAL A 179
VAL A 107
GLN A 382
 None
 0.56A 5qh0A-5wxuA:
undetectable		 5qh0A-5wxuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5wxu 11S GLOBULIN
(Wrightia
tinctoria) 		3 / 3 VAL A 179
VAL A 107
GLN A 382
 None
 0.58A 5qh2A-5wxuA:
undetectable		 5qh2A-5wxuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5wxu 11S GLOBULIN
(Wrightia
tinctoria) 		3 / 3 VAL A 179
VAL A 107
GLN A 382
 None
 0.60A 5qh3A-5wxuA:
undetectable		 5qh3A-5wxuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5wxu 11S GLOBULIN
(Wrightia
tinctoria) 		3 / 3 VAL A 179
VAL A 107
GLN A 382
 None
 0.65A 5qh5A-5wxuA:
undetectable		 5qh5A-5wxuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5wxu 11S GLOBULIN
(Wrightia
tinctoria) 		3 / 3 VAL A 179
VAL A 107
GLN A 382
 None
 0.61A 5qh6A-5wxuA:
undetectable		 5qh6A-5wxuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5wxu 11S GLOBULIN
(Wrightia
tinctoria) 		3 / 3 VAL A 179
VAL A 107
GLN A 382
 None
 0.61A 5qh7A-5wxuA:
undetectable		 5qh7A-5wxuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5wxu 11S GLOBULIN
(Wrightia
tinctoria) 		3 / 3 VAL A 179
VAL A 107
GLN A 382
 None
 0.54A 5qhaA-5wxuA:
undetectable		 5qhaA-5wxuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5wxu 11S GLOBULIN
(Wrightia
tinctoria) 		3 / 3 VAL A 179
VAL A 107
GLN A 382
 None
 0.60A 5qhhA-5wxuA:
undetectable		 5qhhA-5wxuA:
undetectable