SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wzm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4001_1
(SERUM ALBUMIN)		 5wzm GROUP IIE SECRETORY
PHOSPHOLIPASE A2
(Homo
sapiens) 		4 / 5 LYS A 107
ALA A 109
ASP A  37
GLY A  24
 None
None
None
CA  A 209 (-4.2A)
 1.12A 1e7bA-5wzmA:
undetectable		 1e7bA-5wzmA:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4001_1
(SERUM ALBUMIN)		 5wzm GROUP IIE SECRETORY
PHOSPHOLIPASE A2
(Homo
sapiens) 		4 / 5 LYS A 107
ALA A 109
ASP A  37
GLY A  24
 None
None
None
CA  A 209 (-4.2A)
 1.16A 1e7cA-5wzmA:
undetectable		 1e7cA-5wzmA:
9.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 5wzm GROUP IIE SECRETORY
PHOSPHOLIPASE A2
(Homo
sapiens) 		6 / 7 GLY A  28
HIS A  46
ASP A  47
TYR A  50
PRO A  60
LYS A  61
 CA  A 210 (-4.3A)
None
CA  A 210 (-2.2A)
None
CL  A 201 (-3.7A)
CL  A 201 (-4.0A)
 1.05A 1th6A-5wzmA:
20.4		 1th6A-5wzmA:
34.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 5wzm GROUP IIE SECRETORY
PHOSPHOLIPASE A2
(Homo
sapiens) 		5 / 7 GLY A  30
HIS A  46
TYR A  50
PRO A  60
LYS A  61
 CA  A 210 (-4.2A)
None
None
CL  A 201 (-3.7A)
CL  A 201 (-4.0A)
 1.27A 1th6A-5wzmA:
20.4		 1th6A-5wzmA:
34.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 5wzm GROUP IIE SECRETORY
PHOSPHOLIPASE A2
(Homo
sapiens) 		6 / 7 GLY A  28
HIS A  46
ASP A  47
TYR A  50
PRO A  60
LYS A  61
 CA  A 210 (-4.3A)
None
CA  A 210 (-2.2A)
None
CL  A 201 (-3.7A)
CL  A 201 (-4.0A)
 1.05A 2armA-5wzmA:
20.3		 2armA-5wzmA:
34.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2B17_A_DIFA701_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 5wzm GROUP IIE SECRETORY
PHOSPHOLIPASE A2
(Homo
sapiens) 		5 / 10 ALA A  17
GLY A  28
HIS A  46
ASP A  47
PHE A  97
 None
CA  A 210 (-4.3A)
None
CA  A 210 (-2.2A)
None
 0.74A 2b17A-5wzmA:
20.2		 2b17A-5wzmA:
34.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OTH_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 5wzm GROUP IIE SECRETORY
PHOSPHOLIPASE A2
(Homo
sapiens) 		3 / 3 ASP A  47
TYR A  50
LYS A  61
 CA  A 210 (-2.2A)
None
CL  A 201 (-4.0A)
 0.99A 2othA-5wzmA:
19.9		 2othA-5wzmA:
34.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_2
(PHOSPHOLIPASE A2)		 5wzm GROUP IIE SECRETORY
PHOSPHOLIPASE A2
(Homo
sapiens) 		4 / 7 VAL A   3
GLY A  14
ARG A  98
LEU A 101
 None
None
None
TRS  A 211 (-4.0A)
 0.53A 3bjwB-5wzmA:
20.3		 3bjwB-5wzmA:
29.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_2
(PHOSPHOLIPASE A2)		 5wzm GROUP IIE SECRETORY
PHOSPHOLIPASE A2
(Homo
sapiens) 		4 / 6 VAL A   3
GLY A  14
ARG A  98
LEU A 101
 None
None
None
TRS  A 211 (-4.0A)
 0.54A 3bjwE-5wzmA:
20.0		 3bjwE-5wzmA:
29.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 5wzm GROUP IIE SECRETORY
PHOSPHOLIPASE A2
(Homo
sapiens) 		4 / 7 VAL A   3
GLY A  14
ARG A  98
LEU A 101
 None
None
None
TRS  A 211 (-4.0A)
 0.52A 3bjwF-5wzmA:
20.5		 3bjwF-5wzmA:
29.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_3
(PHOSPHOLIPASE A2)		 5wzm GROUP IIE SECRETORY
PHOSPHOLIPASE A2
(Homo
sapiens) 		4 / 7 VAL A   3
GLY A  14
ARG A  98
LEU A 101
 None
None
None
TRS  A 211 (-4.0A)
 0.52A 3bjwH-5wzmA:
20.3		 3bjwH-5wzmA:
29.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FO7_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 5wzm GROUP IIE SECRETORY
PHOSPHOLIPASE A2
(Homo
sapiens) 		5 / 5 HIS A  46
ASP A  47
TYR A  50
PRO A  60
LYS A  61
 None
CA  A 210 (-2.2A)
None
CL  A 201 (-3.7A)
CL  A 201 (-4.0A)
 1.03A 3fo7A-5wzmA:
20.3		 3fo7A-5wzmA:
34.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H1X_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 5wzm GROUP IIE SECRETORY
PHOSPHOLIPASE A2
(Homo
sapiens) 		4 / 5 HIS A  46
ASP A  47
TYR A  50
PRO A  60
 None
CA  A 210 (-2.2A)
None
CL  A 201 (-3.7A)
 0.46A 3h1xA-5wzmA:
20.5		 3h1xA-5wzmA:
34.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 5wzm GROUP IIE SECRETORY
PHOSPHOLIPASE A2
(Homo
sapiens) 		4 / 5 PHE A   5
ILE A   9
GLY A  28
HIS A  46
 None
None
CA  A 210 (-4.3A)
None
 0.61A 3r0lD-5wzmA:
20.9		 3r0lD-5wzmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_2
(-)		 5wzm GROUP IIE SECRETORY
PHOSPHOLIPASE A2
(Homo
sapiens) 		5 / 12 GLY A  28
GLY A  30
TYR A  50
PRO A  60
LYS A  61
 CA  A 210 (-4.3A)
CA  A 210 (-4.2A)
None
CL  A 201 (-3.7A)
CL  A 201 (-4.0A)
 0.98A 6ce2B-5wzmA:
18.5		 6ce2B-5wzmA:
29.75