SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wzr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_2
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN)
IGG2B-KAPPA 40-50
FAB (LIGHT CHAIN))		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 7 THR A 572
ARG A 531
TYR A 626
LEU A 543
 None
 1.11A 1ibgL-5wzrA:
undetectable		 1ibgL-5wzrA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRQ_A_STRA501_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		5 / 11 TYR A 496
LEU A 544
TYR A 541
VAL A 617
LEU A 599
 None
 1.30A 1mrqA-5wzrA:
5.4		 1mrqA-5wzrA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_A_SAMA1401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		5 / 11 LEU A 594
GLY A 547
TYR A 541
PRO A 511
LEU A 599
 None
 1.22A 1p91A-5wzrA:
undetectable		 1p91A-5wzrA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 7 GLY A 509
ARG A 501
ILE A 140
VAL A 138
 None
 0.92A 1rxcC-5wzrA:
undetectable		 1rxcC-5wzrA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 7 GLY A 509
ARG A 501
ILE A 140
VAL A 138
 None
 0.97A 1rxcD-5wzrA:
undetectable		 1rxcD-5wzrA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 7 GLY A 509
ARG A 501
ILE A 140
VAL A 138
 None
 1.06A 1rxcF-5wzrA:
undetectable		 1rxcF-5wzrA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 7 GLY A 509
ARG A 501
ILE A 140
VAL A 138
 None
 1.03A 1rxcL-5wzrA:
undetectable		 1rxcL-5wzrA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_A_LEUA1301_0
(LEUCYL-TRNA
SYNTHETASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 7 TYR A 329
ASP A 322
TYR A 550
HIS A 492
 DJN  A 702 (-4.2A)
CA  A 703 (-2.1A)
None
DJN  A 702 (-3.5A)
 1.48A 2bytA-5wzrA:
undetectable		 2bytA-5wzrA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_D_LEUD1601_0
(LEUCYL-TRNA
SYNTHETASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 7 TYR A 329
ASP A 322
TYR A 550
HIS A 492
 DJN  A 702 (-4.2A)
CA  A 703 (-2.1A)
None
DJN  A 702 (-3.5A)
 1.48A 2bytD-5wzrA:
undetectable		 2bytD-5wzrA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1289_1
(FICOLIN-2)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 6 ARG A 578
ASP A 575
THR A 572
ASP A 537
 None
 0.82A 2j2pE-5wzrA:
undetectable
2j2pF-5wzrA:
undetectable		 2j2pE-5wzrA:
14.15
2j2pF-5wzrA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		5 / 12 ALA A 152
VAL A 153
GLN A 171
THR A 130
ASP A 192
 None
 0.93A 2v95A-5wzrA:
undetectable		 2v95A-5wzrA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A600_1
(ORF12)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		5 / 11 TYR A 217
ALA A 189
GLY A 190
MET A 206
PHE A 208
 None
 1.47A 2xf3A-5wzrA:
2.4		 2xf3A-5wzrA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_B_J01B600_1
(ORF12)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		5 / 11 TYR A 217
ALA A 189
GLY A 190
MET A 206
PHE A 208
 None
 1.46A 2xf3B-5wzrA:
2.4		 2xf3B-5wzrA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_A_J01A600_1
(ORF12)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		5 / 10 TYR A 217
ALA A 189
GLY A 190
MET A 206
PHE A 208
 None
 1.47A 2xfsA-5wzrA:
2.6		 2xfsA-5wzrA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_B_J01B600_1
(ORF12)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		5 / 11 TYR A 217
ALA A 189
GLY A 190
MET A 206
PHE A 208
 None
 1.45A 2xfsB-5wzrA:
2.4		 2xfsB-5wzrA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1437_1
(ORF12)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		5 / 11 TYR A 217
ALA A 189
GLY A 190
MET A 206
PHE A 208
 None
 1.49A 2xh9A-5wzrA:
2.7		 2xh9A-5wzrA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1470_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 5 ARG A 307
ALA A 355
ASP A 354
GLU A 358
 None
 1.34A 2xrzA-5wzrA:
undetectable		 2xrzA-5wzrA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		5 / 6 TYR A 493
ALA A 494
ALA A 162
THR A 161
ASN A 440
 None
 1.23A 3b6hB-5wzrA:
undetectable		 3b6hB-5wzrA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_A_ADNA300_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		5 / 12 ALA A 117
TYR A 223
VAL A 204
GLY A 205
MET A 206
 None
 1.19A 3f8wA-5wzrA:
undetectable		 3f8wA-5wzrA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 6 GLY A 509
ARG A 501
ILE A 140
VAL A 138
 None
 1.03A 3kvvA-5wzrA:
undetectable		 3kvvA-5wzrA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 6 GLY A 509
ARG A 501
ILE A 140
VAL A 138
 None
 0.96A 3kvvB-5wzrA:
undetectable		 3kvvB-5wzrA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 6 GLY A 509
ARG A 501
ILE A 140
VAL A 138
 None
 0.97A 3kvvC-5wzrA:
undetectable		 3kvvC-5wzrA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 6 GLY A 509
ARG A 501
ILE A 140
VAL A 138
 None
 0.91A 3kvvD-5wzrA:
undetectable		 3kvvD-5wzrA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 6 GLY A 509
ARG A 501
ILE A 140
VAL A 138
 None
 0.96A 3kvvE-5wzrA:
undetectable		 3kvvE-5wzrA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 6 GLY A 509
ARG A 501
ILE A 140
VAL A 138
 None
 1.04A 3kvvF-5wzrA:
undetectable		 3kvvF-5wzrA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_1
(PROTEASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		5 / 12 ASP A 554
ASP A 561
GLY A 323
ILE A 274
VAL A 270
 None
DJN  A 702 (-2.9A)
None
None
None
 1.04A 3nu3A-5wzrA:
undetectable		 3nu3A-5wzrA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUO_B_478B478_1
(PROTEASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		5 / 9 ASP A 554
ASP A 561
GLY A 323
ILE A 274
VAL A 270
 None
DJN  A 702 (-2.9A)
None
None
None
 1.11A 3nuoA-5wzrA:
undetectable		 3nuoA-5wzrA:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB1_0
(HEME-BINDING PROTEIN
HUTZ)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 6 ARG A 507
TYR A 541
PHE A 621
LEU A 605
 None
 1.39A 3tgvB-5wzrA:
undetectable		 3tgvB-5wzrA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_C_BEZC1_0
(HEME-BINDING PROTEIN
HUTZ)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 5 ARG A 507
TYR A 541
PHE A 621
LEU A 605
 None
 1.34A 3tgvC-5wzrA:
undetectable		 3tgvC-5wzrA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD392_1
(TETX2 PROTEIN)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 5 HIS A 597
SER A 609
GLN A 607
VAL A 617
 None
 1.38A 4a99D-5wzrA:
undetectable		 4a99D-5wzrA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_A_0LAA602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 5 LEU A 468
LEU A 434
THR A 365
TRP A 324
 None
 1.30A 4do3A-5wzrA:
undetectable		 4do3A-5wzrA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 8 GLY A 509
ARG A 501
ILE A 140
VAL A 138
 None
 0.95A 4e1vA-5wzrA:
undetectable		 4e1vA-5wzrA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 7 GLY A 509
ARG A 501
ILE A 140
VAL A 138
 None
 0.96A 4e1vB-5wzrA:
undetectable		 4e1vB-5wzrA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 8 GLY A 509
ARG A 501
ILE A 140
VAL A 138
 None
 0.96A 4e1vC-5wzrA:
undetectable		 4e1vC-5wzrA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 8 GLY A 509
ARG A 501
ILE A 140
VAL A 138
 None
 1.00A 4e1vD-5wzrA:
undetectable		 4e1vD-5wzrA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 8 GLY A 509
ARG A 501
ILE A 140
VAL A 138
 None
 0.98A 4e1vE-5wzrA:
undetectable		 4e1vE-5wzrA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 6 GLY A 509
ARG A 501
ILE A 140
VAL A 138
 None
 1.00A 4e1vF-5wzrA:
undetectable		 4e1vF-5wzrA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 8 GLY A 509
ARG A 501
ILE A 140
VAL A 138
 None
 0.96A 4e1vH-5wzrA:
undetectable		 4e1vH-5wzrA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 7 ASP A 561
ASP A 322
ASP A 371
ASP A 330
 DJN  A 702 (-2.9A)
CA  A 703 (-2.1A)
DJN  A 702 (-3.1A)
DJN  A 702 (-2.6A)
 1.17A 4feuB-5wzrA:
undetectable		 4feuB-5wzrA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 8 ASP A 561
ASP A 322
ASP A 371
ASP A 330
 DJN  A 702 (-2.9A)
CA  A 703 (-2.1A)
DJN  A 702 (-3.1A)
DJN  A 702 (-2.6A)
 1.20A 4feuF-5wzrA:
undetectable		 4feuF-5wzrA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 7 ASP A 561
ASP A 322
ASP A 371
ASP A 330
 DJN  A 702 (-2.9A)
CA  A 703 (-2.1A)
DJN  A 702 (-3.1A)
DJN  A 702 (-2.6A)
 1.19A 4fevB-5wzrA:
undetectable		 4fevB-5wzrA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 7 ASP A 561
ASP A 322
ASP A 371
ASP A 330
 DJN  A 702 (-2.9A)
CA  A 703 (-2.1A)
DJN  A 702 (-3.1A)
DJN  A 702 (-2.6A)
 1.23A 4fevD-5wzrA:
undetectable		 4fevD-5wzrA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 7 ASP A 561
ASP A 322
ASP A 371
ASP A 330
 DJN  A 702 (-2.9A)
CA  A 703 (-2.1A)
DJN  A 702 (-3.1A)
DJN  A 702 (-2.6A)
 1.21A 4fevF-5wzrA:
undetectable		 4fevF-5wzrA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 7 ASP A 561
ASP A 322
ASP A 371
ASP A 330
 DJN  A 702 (-2.9A)
CA  A 703 (-2.1A)
DJN  A 702 (-3.1A)
DJN  A 702 (-2.6A)
 1.17A 4fewB-5wzrA:
undetectable		 4fewB-5wzrA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 8 ASP A 561
ASP A 322
ASP A 371
ASP A 330
 DJN  A 702 (-2.9A)
CA  A 703 (-2.1A)
DJN  A 702 (-3.1A)
DJN  A 702 (-2.6A)
 1.21A 4fewF-5wzrA:
undetectable		 4fewF-5wzrA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEX_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 7 ASP A 561
ASP A 322
ASP A 371
ASP A 330
 DJN  A 702 (-2.9A)
CA  A 703 (-2.1A)
DJN  A 702 (-3.1A)
DJN  A 702 (-2.6A)
 1.21A 4fexB-5wzrA:
undetectable		 4fexB-5wzrA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_1
(METHYLTRANSFERASE
NSUN4)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		3 / 3 ASP A 128
ARG A 173
ASP A 122
 None
 0.80A 4fp9D-5wzrA:
undetectable		 4fp9D-5wzrA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_1
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		3 / 3 ASP A 128
ARG A 173
ASP A 122
 None
 0.81A 4fzvA-5wzrA:
undetectable		 4fzvA-5wzrA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 8 ASP A 561
ASP A 322
ASP A 371
ASP A 330
 DJN  A 702 (-2.9A)
CA  A 703 (-2.1A)
DJN  A 702 (-3.1A)
DJN  A 702 (-2.6A)
 1.18A 4gkhD-5wzrA:
undetectable		 4gkhD-5wzrA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 7 ASP A 561
ASP A 322
ASP A 371
ASP A 330
 DJN  A 702 (-2.9A)
CA  A 703 (-2.1A)
DJN  A 702 (-3.1A)
DJN  A 702 (-2.6A)
 1.21A 4gkhG-5wzrA:
undetectable		 4gkhG-5wzrA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 6 ASP A 561
ASP A 322
ASP A 371
ASP A 330
 DJN  A 702 (-2.9A)
CA  A 703 (-2.1A)
DJN  A 702 (-3.1A)
DJN  A 702 (-2.6A)
 1.18A 4gkhJ-5wzrA:
undetectable		 4gkhJ-5wzrA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 8 ASP A 561
ASP A 322
ASP A 371
ASP A 330
 DJN  A 702 (-2.9A)
CA  A 703 (-2.1A)
DJN  A 702 (-3.1A)
DJN  A 702 (-2.6A)
 1.19A 4gkiC-5wzrA:
undetectable		 4gkiC-5wzrA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1X_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 8 TYR A 496
TYR A 541
VAL A 617
LEU A 599
 None
 0.82A 4l1xA-5wzrA:
7.7		 4l1xA-5wzrA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QC6_B_KANB201_2
(BIFUNCTIONAL AAC/APH)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		3 / 3 LEU A 410
ASP A 413
TYR A 414
 None
 0.57A 4qc6B-5wzrA:
undetectable		 4qc6B-5wzrA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_B_ACTB403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		3 / 3 ARG A  41
ASP A 111
ARG A 109
 None
 0.67A 4wq4B-5wzrA:
undetectable		 4wq4B-5wzrA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X61_A_SAMA701_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 5 TYR A 165
TYR A 191
GLU A 479
ASP A 561
 None
None
None
DJN  A 702 (-2.9A)
 1.48A 4x61A-5wzrA:
0.0		 4x61A-5wzrA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		5 / 10 ASP A 367
HIS A 320
HIS A 271
HIS A 492
ALA A 556
 None
CA  A 703 (-3.3A)
CA  A 703 (-3.2A)
DJN  A 702 (-3.5A)
DJN  A 702 ( 4.0A)
 1.30A 4yhaB-5wzrA:
undetectable		 4yhaB-5wzrA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 6 ASP A 322
HIS A 366
TYR A 318
TYR A 550
 CA  A 703 (-2.1A)
CA  A 703 ( 3.3A)
None
None
 1.13A 5ih0A-5wzrA:
2.3		 5ih0A-5wzrA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 8 HIS A 271
HIS A 320
LEU A 319
GLY A 364
 CA  A 703 (-3.2A)
CA  A 703 (-3.3A)
None
None
 0.79A 5m8rC-5wzrA:
undetectable		 5m8rC-5wzrA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_D_ACTD301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 4 ASP A 322
HIS A 271
HIS A 492
HIS A 366
 CA  A 703 (-2.1A)
CA  A 703 (-3.2A)
DJN  A 702 (-3.5A)
CA  A 703 ( 3.3A)
 1.31A 5ncdD-5wzrA:
3.9		 5ncdD-5wzrA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA601_0
(THIOCYANATE
DEHYDROGENASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		3 / 3 HIS A 271
ASP A 322
HIS A 366
 CA  A 703 (-3.2A)
CA  A 703 (-2.1A)
CA  A 703 ( 3.3A)
 0.79A 5oexA-5wzrA:
2.0		 5oexA-5wzrA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB601_0
(THIOCYANATE
DEHYDROGENASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		3 / 3 HIS A 271
ASP A 322
HIS A 366
 CA  A 703 (-3.2A)
CA  A 703 (-2.1A)
CA  A 703 ( 3.3A)
 0.79A 5oexB-5wzrA:
undetectable		 5oexB-5wzrA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD601_0
(THIOCYANATE
DEHYDROGENASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		3 / 3 HIS A 271
ASP A 322
HIS A 366
 CA  A 703 (-3.2A)
CA  A 703 (-2.1A)
CA  A 703 ( 3.3A)
 0.76A 5oexD-5wzrA:
3.3		 5oexD-5wzrA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		3 / 3 TYR A 217
ARG A 455
THR A 453
 None
 1.03A 5z84J-5wzrA:
undetectable		 5z84J-5wzrA:
7.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPL_B_PA1B605_1
(LIPID A EXPORT
ATP-BINDING/PERMEASE
PROTEIN MSBA)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		3 / 3 ARG A 158
ARG A 219
ARG A 112
 None
 1.03A 6bplA-5wzrA:
undetectable
6bplB-5wzrA:
1.9		 6bplA-5wzrA:
8.72
6bplB-5wzrA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		3 / 3 GLN A 136
TYR A 515
ASN A 516
 None
 1.04A 6dwdC-5wzrA:
undetectable		 6dwdC-5wzrA:
21.75