SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5x00'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_A_KKKA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5x00 NUCLEOSIDE
DIPHOSPHATE KINASE
(Vibrio
cholerae) 		5 / 12 GLY A  49
ALA A  47
THR A  68
ILE A  72
ILE A  10
 None
 1.27A 3ld6A-5x00A:
undetectable		 3ld6A-5x00A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M6T_A_SAMA201_0
(RNA POLYMERASE
II-ASSOCIATED FACTOR
1 HOMOLOG, LINKER,
RNA
POLYMERASE-ASSOCIATE
D PROTEIN LEO1)		 5x00 NUCLEOSIDE
DIPHOSPHATE KINASE
(Vibrio
cholerae) 		4 / 4 ILE A 129
VAL A  74
VAL A  76
ARG A   5
 None
 1.35A 4m6tA-5x00A:
undetectable		 4m6tA-5x00A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_A_ASCA303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 5x00 NUCLEOSIDE
DIPHOSPHATE KINASE
(Vibrio
cholerae) 		4 / 7 PHE A   7
HIS A 117
ILE A   9
TYR A  51
 None
 1.40A 4o7gA-5x00A:
undetectable
4o7gB-5x00A:
undetectable		 4o7gA-5x00A:
undetectable
4o7gB-5x00A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_B_ASCB304_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 5x00 NUCLEOSIDE
DIPHOSPHATE KINASE
(Vibrio
cholerae) 		4 / 6 PHE A   7
HIS A 117
ILE A   9
TYR A  51
 None
 1.42A 4o7gB-5x00A:
undetectable		 4o7gB-5x00A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_F_FK5F201_1
(FK506-BINDING
PROTEIN 1)		 5x00 NUCLEOSIDE
DIPHOSPHATE KINASE
(Vibrio
cholerae) 		5 / 12 PHE A 133
ILE A  34
TYR A  24
ILE A  20
ILE A  10
 None
 1.13A 5hw8B-5x00A:
undetectable
5hw8F-5x00A:
undetectable
5hw8G-5x00A:
undetectable		 5hw8B-5x00A:
20.87
5hw8F-5x00A:
20.87
5hw8G-5x00A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_2
(FK506-BINDING
PROTEIN 1)		 5x00 NUCLEOSIDE
DIPHOSPHATE KINASE
(Vibrio
cholerae) 		5 / 11 PHE A 133
ILE A  34
TYR A  24
ILE A  20
ILE A  23
 None
 1.06A 5hw8G-5x00A:
undetectable		 5hw8G-5x00A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_1
(METHYLTRANSFERASE)		 5x00 NUCLEOSIDE
DIPHOSPHATE KINASE
(Vibrio
cholerae) 		4 / 7 LEU A  63
SER A  69
ILE A  10
ASN A 114
 None
 0.90A 5n5dA-5x00A:
undetectable		 5n5dA-5x00A:
undetectable