SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5x15'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_1
(N,N-DIMETHYLGLYCINE
OXIDASE)		 5x15 PUTATIVE TRANSFERASE
(Streptomyces
coelicolor) 		3 / 3 ASP A 209
THR A  50
GLU A 235
 None
 0.85A 1pj7A-5x15A:
undetectable		 1pj7A-5x15A:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_2
(SECRETED ASPARTIC
PROTEASE)		 5x15 PUTATIVE TRANSFERASE
(Streptomyces
coelicolor) 		4 / 7 VAL A 139
ILE A 169
THR A 174
THR A 175
 None
 0.92A 3tneB-5x15A:
undetectable		 3tneB-5x15A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 5x15 PUTATIVE TRANSFERASE
(Streptomyces
coelicolor) 		4 / 8 GLY A 147
ASP A 119
GLY A 118
VAL A  77
 None
 0.80A 4c5nC-5x15A:
undetectable		 4c5nC-5x15A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_B_FOLB703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5x15 PUTATIVE TRANSFERASE
(Streptomyces
coelicolor) 		5 / 10 VAL A 214
ALA A 208
SER A  66
ARG A  62
VAL A 215
 None
 1.48A 4eilB-5x15A:
undetectable		 4eilB-5x15A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_D_FOLD703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5x15 PUTATIVE TRANSFERASE
(Streptomyces
coelicolor) 		5 / 10 VAL A 214
ALA A 208
SER A  66
ARG A  62
VAL A 215
 None
 1.42A 4eilD-5x15A:
undetectable		 4eilD-5x15A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 5x15 PUTATIVE TRANSFERASE
(Streptomyces
coelicolor) 		4 / 8 GLY A 149
GLY A  79
LEU A 205
VAL A 215
 None
 0.87A 4fgzB-5x15A:
undetectable		 4fgzB-5x15A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUH_A_ACTA610_0
(SERUM ALBUMIN)		 5x15 PUTATIVE TRANSFERASE
(Streptomyces
coelicolor) 		3 / 3 VAL A  46
SER A  47
THR A  50
 None
 0.36A 4luhA-5x15A:
undetectable		 4luhA-5x15A:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7I_A_STIA1001_2
(MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR)		 5x15 PUTATIVE TRANSFERASE
(Streptomyces
coelicolor) 		4 / 5 LEU A 184
VAL A 152
TYR A 126
ARG A 140
 None
 0.93A 4r7iA-5x15A:
undetectable		 4r7iA-5x15A:
22.13