SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5x2b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA8_0
(GRAMICIDIN A)		 5x2b SULFOTRANSFERASE
(Mus
musculus) 		3 / 4 VAL D 123
TRP D 158
TRP D 252
 None
 1.33A 1gmkA-5x2bD:
undetectable
1gmkB-5x2bD:
undetectable		 1gmkA-5x2bD:
undetectable
1gmkB-5x2bD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JGS_A_SALA256_1
(MULTIPLE ANTIBIOTIC
RESISTANCE PROTEIN
MARR)		 5x2b SULFOTRANSFERASE
(Mus
musculus) 		4 / 7 VAL D  56
LEU D 190
THR D 194
LEU D 197
 None
 0.99A 1jgsA-5x2bD:
undetectable		 1jgsA-5x2bD:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 5x2b SULFOTRANSFERASE
(Mus
musculus) 		3 / 3 TRP D 252
TYR D 255
LEU D 145
 None
 0.91A 1kxhA-5x2bD:
undetectable		 1kxhA-5x2bD:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)		 5x2b SULFOTRANSFERASE
(Mus
musculus) 		3 / 3 ASP D  39
PHE D  33
ARG D  89
 CA  D 304 (-3.3A)
None
CA  D 304 (-4.3A)
 0.90A 2a3aA-5x2bD:
undetectable		 2a3aA-5x2bD:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5x2b SULFOTRANSFERASE
(Mus
musculus) 		4 / 6 LEU D  30
PHE D  33
PHE D  79
LEU D  26
 None
 1.08A 3wg7C-5x2bD:
undetectable
3wg7J-5x2bD:
undetectable		 3wg7C-5x2bD:
undetectable
3wg7J-5x2bD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMA_D_ADND604_1
(PYRUVATE KINASE)		 5x2b SULFOTRANSFERASE
(Mus
musculus) 		3 / 3 ARG D 240
GLU D  55
ASN D 221
 None
 0.89A 4imaD-5x2bD:
undetectable		 4imaD-5x2bD:
10.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5x2b SULFOTRANSFERASE
(Mus
musculus) 		4 / 7 LEU D  73
PRO D  46
SER D  44
VAL D 154
 None
None
A3P  D 301 ( 4.9A)
None
 1.13A 4klrA-5x2bD:
2.1		 4klrA-5x2bD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 5x2b SULFOTRANSFERASE
(Mus
musculus) 		4 / 7 TYR D 155
ILE D  91
LEU D  27
LEU D  30
 None
 0.86A 4l1wA-5x2bD:
undetectable		 4l1wA-5x2bD:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_A_ACTA701_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 5x2b SULFOTRANSFERASE
(Mus
musculus) 		3 / 3 LYS D  78
LYS D 230
SER D  69
 None
 1.39A 5odiA-5x2bD:
undetectable		 5odiA-5x2bD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5x2b SULFOTRANSFERASE
(Mus
musculus) 		4 / 6 LEU D  30
PHE D  33
PHE D  79
LEU D  26
 None
 1.13A 5x19P-5x2bD:
undetectable		 5x19P-5x2bD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_C_9F2C302_1
(BETA-LACTAMASE)		 5x2b SULFOTRANSFERASE
(Mus
musculus) 		5 / 10 ARG D  89
THR D  68
ILE D  71
PRO D  70
ASP D  31
 CA  D 304 (-4.3A)
None
None
None
CA  D 302 ( 4.0A)
 1.48A 6b5yC-5x2bD:
undetectable
6b5yD-5x2bD:
undetectable		 6b5yC-5x2bD:
25.00
6b5yD-5x2bD:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 5x2b SULFOTRANSFERASE
(Mus
musculus) 		4 / 6 VAL D 162
ASN D 117
PRO D 118
GLU D 180
 None
 1.25A 6h7uA-5x2bD:
undetectable		 6h7uA-5x2bD:
undetectable