SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5x2d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_A_NCAA900_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 5x2d TEGUMENTAL PROTEIN
20.8 KDA
(Clonorchis
sinensis) 		4 / 5 ILE A  92
PHE A 161
PHE A 172
ILE A  89
 None
 1.02A 2hjhA-5x2dA:
undetectable		 2hjhA-5x2dA:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_2
(GLUCOCORTICOID
RECEPTOR 2)		 5x2d TEGUMENTAL PROTEIN
20.8 KDA
(Clonorchis
sinensis) 		3 / 3 MET A 159
MET A 143
PHE A 136
 None
 1.36A 3gn8A-5x2dA:
undetectable		 3gn8A-5x2dA:
17.84