SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5x2g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 8 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 1.00A 1dz9A-5x2gA:
undetectable		 1dz9A-5x2gA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 8 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 1.08A 1o76B-5x2gA:
undetectable		 1o76B-5x2gA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 8 SER A 922
ASN A 926
ASN A 910
ASP A 891
 None
 1.32A 1p6kA-5x2gA:
undetectable		 1p6kA-5x2gA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 8 SER A 922
ASN A 926
ASN A 910
ASP A 891
 None
 1.29A 1rs6A-5x2gA:
undetectable		 1rs6A-5x2gA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 8 SER A 922
ASN A 926
ASN A 910
ASP A 891
 None
 1.24A 1rs6B-5x2gA:
2.0		 1rs6B-5x2gA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 8 SER A 922
ASN A 926
ASN A 910
ASP A 891
 None
 1.27A 1rs7B-5x2gA:
undetectable		 1rs7B-5x2gA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 7 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 0.91A 1t85A-5x2gA:
undetectable		 1t85A-5x2gA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 7 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 0.99A 1t87A-5x2gA:
undetectable		 1t87A-5x2gA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 8 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 0.94A 1uyuA-5x2gA:
undetectable		 1uyuA-5x2gA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 8 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 1.10A 1uyuB-5x2gA:
undetectable		 1uyuB-5x2gA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 7 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 0.97A 1yrcA-5x2gA:
undetectable		 1yrcA-5x2gA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 7 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 1.01A 1yrdA-5x2gA:
undetectable		 1yrdA-5x2gA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 8 SER A 922
ASN A 926
ASN A 910
ASP A 891
 None
 1.29A 1zzqA-5x2gA:
undetectable		 1zzqA-5x2gA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 8 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 0.87A 2a1oA-5x2gA:
undetectable		 2a1oA-5x2gA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_A_SAMA500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		5 / 11 GLU A 389
ILE A 362
ASP A 364
ALA A 235
ASP A 358
 None
 1.17A 2admA-5x2gA:
undetectable		 2admA-5x2gA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRD_A_MIYA2001_1
(ACRB)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		5 / 9 GLY A  10
GLU A 479
ILE A 643
ALA A 455
VAL A 452
 None
 1.34A 2drdA-5x2gA:
3.0		 2drdA-5x2gA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 6 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 0.96A 2feuA-5x2gA:
undetectable		 2feuA-5x2gA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 7 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 0.93A 2feuB-5x2gA:
undetectable		 2feuB-5x2gA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_NCAA493_0
(CHORISMATE SYNTHASE)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		5 / 11 THR A 651
ILE A 476
ILE A   9
ALA A 644
VAL A 679
 None
 1.17A 2qhfA-5x2gA:
undetectable		 2qhfA-5x2gA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1357_1
(PROSTAGLANDIN
REDUCTASE 2)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 6 LEU A 261
ASN A 353
LYS A 357
ASP A 358
 None
 1.48A 2w98A-5x2gA:
undetectable
2w98B-5x2gA:
undetectable		 2w98A-5x2gA:
16.85
2w98B-5x2gA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 6 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 1.10A 2zuhA-5x2gA:
undetectable		 2zuhA-5x2gA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 6 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 1.01A 2zuiA-5x2gA:
undetectable		 2zuiA-5x2gA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 7 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 1.00A 2zwtA-5x2gA:
undetectable		 2zwtA-5x2gA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 7 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 0.99A 2zwuA-5x2gA:
undetectable		 2zwuA-5x2gA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_2
(PHOSPHOLIPASE A2)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 6 VAL A 452
VAL A 451
ARG A 454
ARG A  48
 None
None
None
G  B  70 ( 3.6A)
 1.14A 3bjwF-5x2gA:
undetectable		 3bjwF-5x2gA:
9.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_A_ADNA300_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		5 / 12 ALA A  17
GLY A  15
VAL A  29
GLY A  28
VAL A 712
 None
 1.16A 3f8wA-5x2gA:
undetectable		 3f8wA-5x2gA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_C_ADNC302_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		5 / 12 ALA A  17
GLY A  15
VAL A  29
GLY A  28
VAL A 712
 None
 1.17A 3f8wC-5x2gA:
undetectable		 3f8wC-5x2gA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 7 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 0.96A 3fwfA-5x2gA:
undetectable		 3fwfA-5x2gA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 7 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 0.97A 3fwfB-5x2gA:
undetectable		 3fwfB-5x2gA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 7 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 1.03A 3fwiA-5x2gA:
undetectable		 3fwiA-5x2gA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 7 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 0.99A 3fwjA-5x2gA:
undetectable		 3fwjA-5x2gA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 7 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 0.95A 3l63A-5x2gA:
undetectable		 3l63A-5x2gA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O02_B_JN3B1_1
(CELL INVASION
PROTEIN SIPD)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		5 / 10 ARG A 270
ALA A 267
LEU A 291
LEU A 295
VAL A 298
 U  B   6 ( 3.7A)
None
None
None
None
 0.77A 3o02A-5x2gA:
0.9
3o02B-5x2gA:
undetectable		 3o02A-5x2gA:
17.15
3o02B-5x2gA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA5_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		3 / 3 LYS A 923
SER A 932
GLN A 935
 None
 1.28A 3si7A-5x2gA:
undetectable		 3si7A-5x2gA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 7 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 0.94A 3wrhA-5x2gA:
undetectable		 3wrhA-5x2gA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 7 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 0.96A 3wrjA-5x2gA:
undetectable		 3wrjA-5x2gA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 7 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 0.97A 3wrlA-5x2gA:
undetectable		 3wrlA-5x2gA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 7 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 0.96A 3wrlE-5x2gA:
undetectable		 3wrlE-5x2gA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 7 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 0.96A 3wrmA-5x2gA:
undetectable		 3wrmA-5x2gA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 7 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 0.96A 3wrmF-5x2gA:
undetectable		 3wrmF-5x2gA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 6 PHE A   7
LEU A 467
VAL A 473
VAL A 679
 None
 1.11A 4ek1A-5x2gA:
undetectable		 4ek1A-5x2gA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA503_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 6 ARG A 128
ILE A 195
VAL A 162
LEU A 166
 A  B  45 ( 3.3A)
None
None
None
 0.95A 4em2A-5x2gA:
undetectable		 4em2A-5x2gA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 6 PHE A   7
LEU A 467
VAL A 473
VAL A 679
 None
 1.11A 4g3rA-5x2gA:
undetectable		 4g3rA-5x2gA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 6 PHE A   7
LEU A 467
VAL A 473
VAL A 679
 None
 1.17A 4kkyX-5x2gA:
undetectable		 4kkyX-5x2gA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 8 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 1.06A 4l4bA-5x2gA:
undetectable		 4l4bA-5x2gA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 6 PHE A   7
LEU A 467
VAL A 473
VAL A 679
 None
 1.12A 4l4cA-5x2gA:
undetectable		 4l4cA-5x2gA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 8 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 1.00A 4l4cB-5x2gA:
undetectable		 4l4cB-5x2gA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 8 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 1.05A 4l4dA-5x2gA:
undetectable		 4l4dA-5x2gA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 8 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 0.90A 4l4eA-5x2gA:
undetectable		 4l4eA-5x2gA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 8 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 0.93A 4l4fA-5x2gA:
undetectable		 4l4fA-5x2gA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 7 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 0.94A 4l4gA-5x2gA:
undetectable		 4l4gA-5x2gA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_A_GLYA403_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 4 LEU A 156
LEU A 166
GLY A 163
GLU A 164
 None
 1.11A 5hhjA-5x2gA:
undetectable		 5hhjA-5x2gA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_C_FK5C201_1
(FK506-BINDING
PROTEIN 1)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		5 / 10 TYR A 375
ASP A 358
ILE A 339
TYR A 335
LEU A 385
 None
 1.35A 5hw8C-5x2gA:
undetectable
5hw8H-5x2gA:
undetectable		 5hw8C-5x2gA:
10.57
5hw8H-5x2gA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		5 / 9 LEU A 938
PHE A 939
VAL A 907
HIS A 924
ILE A 896
 None
 1.17A 5om2A-5x2gA:
undetectable
5om2B-5x2gA:
undetectable		 5om2A-5x2gA:
6.85
5om2B-5x2gA:
4.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 7 PHE A   7
TYR A 459
THR A 651
LEU A 435
 None
 0.94A 5wk9A-5x2gA:
undetectable		 5wk9A-5x2gA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 8 ARG A  52
ARG A  60
ARG A 129
GLN A 197
 C  B  15 ( 3.5A)
U  B  16 ( 2.8A)
G  B  18 ( 3.8A)
None
 1.09A 6fbvD-5x2gA:
undetectable		 6fbvD-5x2gA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		 5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
(Campylobacter
jejuni) 		4 / 6 THR A 309
LEU A 312
THR A 327
LEU A 291
 None
 1.15A 6mvxA-5x2gA:
undetectable
6mvxB-5x2gA:
3.0
6mvxC-5x2gA:
3.0		 6mvxA-5x2gA:
14.85
6mvxB-5x2gA:
14.85
6mvxC-5x2gA:
14.85