SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5x2o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		3 / 3 GLN B 167
ILE B 432
HIS B 395
 None
 0.72A 1fm9A-5x2oB:
undetectable		 1fm9A-5x2oB:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JGS_A_SALA256_1
(MULTIPLE ANTIBIOTIC
RESISTANCE PROTEIN
MARR)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		4 / 7 VAL B  78
LEU B 333
THR B 337
LEU B 340
 None
 0.91A 1jgsA-5x2oB:
undetectable		 1jgsA-5x2oB:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		3 / 3 GLN B 167
ILE B 432
HIS B 395
 None
 0.74A 1k74A-5x2oB:
undetectable		 1k74A-5x2oB:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		4 / 5 ILE B 304
TRP B 302
VAL B 277
SER B 378
 None
 1.23A 1rs7A-5x2oB:
undetectable		 1rs7A-5x2oB:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_K_BEZK4387_0
(CES1 PROTEIN)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		3 / 3 TRP B 410
LEU B 400
LYS B 420
 None
 0.90A 1yajK-5x2oB:
3.4		 1yajK-5x2oB:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		3 / 3 TRP B  23
GLU B  85
TYR B  81
 None
 1.26A 2a3aA-5x2oB:
undetectable		 2a3aA-5x2oB:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		5 / 12 GLN B 380
THR B 382
GLY B  74
LEU B 333
LEU B 373
 None
 1.22A 2zw9B-5x2oB:
2.4		 2zw9B-5x2oB:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		4 / 7 TRP B 302
PHE B 284
SER B 299
VAL B 272
 None
 1.44A 3dqtA-5x2oB:
undetectable
3dqtB-5x2oB:
undetectable		 3dqtA-5x2oB:
20.84
3dqtB-5x2oB:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		4 / 6 ILE B  86
PHE B  24
PHE B 336
TYR B  81
 None
 1.27A 3elzB-5x2oB:
undetectable		 3elzB-5x2oB:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		5 / 10 GLY B 225
GLN B 227
VAL B 272
VAL B 214
GLN B 243
 None
 1.29A 3fhjA-5x2oB:
undetectable		 3fhjA-5x2oB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		5 / 10 GLY B 225
GLN B 227
VAL B 272
VAL B 214
GLN B 243
 None
 1.28A 3fhjB-5x2oB:
undetectable		 3fhjB-5x2oB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		5 / 10 GLY B 225
GLN B 227
VAL B 272
VAL B 214
GLN B 243
 None
 1.27A 3fhjC-5x2oB:
undetectable		 3fhjC-5x2oB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		5 / 10 GLY B 225
GLN B 227
VAL B 272
VAL B 214
GLN B 243
 None
 1.28A 3fhjE-5x2oB:
undetectable		 3fhjE-5x2oB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		5 / 9 GLY B 225
GLN B 227
VAL B 272
VAL B 214
GLN B 243
 None
 1.28A 3fi0A-5x2oB:
undetectable		 3fi0A-5x2oB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		5 / 9 GLY B 225
GLN B 227
VAL B 272
VAL B 214
GLN B 243
 None
 1.30A 3fi0C-5x2oB:
undetectable		 3fi0C-5x2oB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		5 / 9 GLY B 225
GLN B 227
VAL B 272
VAL B 214
GLN B 243
 None
 1.32A 3fi0M-5x2oB:
undetectable		 3fi0M-5x2oB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		5 / 9 GLY B 225
GLN B 227
VAL B 272
VAL B 214
GLN B 243
 None
 1.28A 3fi0N-5x2oB:
undetectable		 3fi0N-5x2oB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_O_TRPO1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		5 / 9 GLY B 225
GLN B 227
VAL B 272
VAL B 214
GLN B 243
 None
 1.28A 3fi0O-5x2oB:
undetectable		 3fi0O-5x2oB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I9J_B_NCAB302_0
(ADP-RIBOSYL CYCLASE)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		4 / 6 LEU B 276
GLU B 219
SER B 301
PHE B 274
 ARG  B 951 (-4.5A)
None
None
None
 1.25A 3i9jB-5x2oB:
2.2		 3i9jB-5x2oB:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3004_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		4 / 5 LYS B 290
ILE B 263
PHE B 283
GLU B 286
 None
 1.18A 3kp6A-5x2oB:
undetectable
3kp6B-5x2oB:
undetectable		 3kp6A-5x2oB:
16.67
3kp6B-5x2oB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW4_A_TICA600_1
(CYTOCHROME P450 2B4)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		6 / 11 ILE B 297
ILE B 452
SER B 463
ILE B 474
VAL B 464
GLY B 465
 None
 0.95A 3kw4A-5x2oB:
0.2		 3kw4A-5x2oB:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_B_CLMB221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		5 / 12 SER B 169
PHE B 170
SER B 150
LEU B 276
VAL B 277
 None
None
ARG  B 951 (-2.8A)
ARG  B 951 (-4.5A)
None
 1.27A 3u9fB-5x2oB:
undetectable
3u9fC-5x2oB:
undetectable		 3u9fB-5x2oB:
15.21
3u9fC-5x2oB:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_J_CLMJ221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		5 / 12 SER B 169
PHE B 170
SER B 150
LEU B 276
VAL B 277
 None
None
ARG  B 951 (-2.8A)
ARG  B 951 (-4.5A)
None
 1.25A 3u9fJ-5x2oB:
undetectable
3u9fK-5x2oB:
undetectable		 3u9fJ-5x2oB:
15.21
3u9fK-5x2oB:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		4 / 7 TRP B 302
PHE B 284
SER B 299
VAL B 272
 None
 1.46A 4k5jA-5x2oB:
undetectable
4k5jB-5x2oB:
undetectable		 4k5jA-5x2oB:
20.66
4k5jB-5x2oB:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM7_A_29JA603_1
(TRANSPORTER)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		5 / 10 TYR B 467
TYR B 449
SER B 300
GLY B 322
ASP B 198
 None
None
ARG  B 951 ( 4.6A)
None
None
 1.43A 4mm7A-5x2oB:
undetectable		 4mm7A-5x2oB:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA603_1
(TRANSPORTER)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		5 / 10 TYR B 467
TYR B 449
SER B 300
GLY B 322
ASP B 198
 None
None
ARG  B 951 ( 4.6A)
None
None
 1.47A 4mmcA-5x2oB:
undetectable		 4mmcA-5x2oB:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		5 / 10 VAL B 386
ALA B 389
GLY B  72
SER B 169
GLY B 146
 None
 1.33A 4mmdA-5x2oB:
0.9		 4mmdA-5x2oB:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_A_SAMA603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		4 / 7 ASP B  71
THR B 382
ILE B 324
ASP B 325
 None
 0.98A 4pcuA-5x2oB:
undetectable		 4pcuA-5x2oB:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_A_SAMA603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		4 / 7 PRO B  45
THR B 382
ILE B 324
ASP B 325
 CL  B 971 ( 4.0A)
None
None
None
 1.07A 4pcuA-5x2oB:
undetectable		 4pcuA-5x2oB:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R82_A_ACTA205_0
(OXIDOREDUCTASE)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		4 / 5 SER B 169
GLY B 171
ARG B 188
PHE B 186
 None
ARG  B 951 (-4.2A)
None
None
 1.08A 4r82A-5x2oB:
undetectable
4r82B-5x2oB:
undetectable		 4r82A-5x2oB:
18.60
4r82B-5x2oB:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1007_1
(SERUM ALBUMIN)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		5 / 9 TRP B 456
LEU B 461
ILE B 324
SER B 301
ALA B 298
 None
 1.38A 4z69A-5x2oB:
undetectable		 4z69A-5x2oB:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		4 / 7 TRP B 302
PHE B 284
SER B 299
VAL B 272
 None
 1.42A 5adlA-5x2oB:
undetectable
5adlB-5x2oB:
undetectable		 5adlA-5x2oB:
20.66
5adlB-5x2oB:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		4 / 7 TRP B 302
PHE B 284
SER B 299
VAL B 272
 None
 1.42A 5fj3A-5x2oB:
undetectable
5fj3B-5x2oB:
undetectable		 5fj3A-5x2oB:
20.66
5fj3B-5x2oB:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_A_SAMA801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		5 / 12 ILE B 317
GLY B 318
THR B 319
TYR B 309
VAL B 308
 None
 1.07A 5hw4A-5x2oB:
2.6		 5hw4A-5x2oB:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_C_SAMC801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		5 / 12 ILE B 317
GLY B 318
THR B 319
TYR B 309
VAL B 308
 None
 1.04A 5hw4C-5x2oB:
3.4		 5hw4C-5x2oB:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_2
(CDL2.3A)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		4 / 8 ILE B  46
PRO B  45
ILE B 145
TYR B 103
 None
CL  B 971 ( 4.0A)
None
None
 0.88A 5ieoA-5x2oB:
undetectable		 5ieoA-5x2oB:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		4 / 7 TRP B 302
PHE B 284
SER B 299
VAL B 272
 None
 1.43A 5vv7A-5x2oB:
undetectable
5vv7B-5x2oB:
undetectable		 5vv7A-5x2oB:
20.66
5vv7B-5x2oB:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		4 / 7 TRP B 302
PHE B 284
SER B 299
VAL B 272
 None
 1.43A 5vvnA-5x2oB:
undetectable
5vvnB-5x2oB:
undetectable		 5vvnA-5x2oB:
20.66
5vvnB-5x2oB:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_F_MTXF402_1
(THYMIDYLATE SYNTHASE)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		5 / 12 LEU B 160
GLY B 161
PHE B 162
ALA B 143
VAL B 142
 None
 0.99A 5x66F-5x2oB:
undetectable		 5x66F-5x2oB:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB501_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		4 / 7 SER B 299
VAL B 272
TRP B 302
PHE B 284
 None
 1.38A 6av6A-5x2oB:
undetectable
6av6B-5x2oB:
undetectable		 6av6A-5x2oB:
10.46
6av6B-5x2oB:
10.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		4 / 7 TRP B 302
PHE B 284
SER B 299
VAL B 272
 None
 1.41A 6av6C-5x2oB:
undetectable
6av6D-5x2oB:
undetectable		 6av6C-5x2oB:
10.46
6av6D-5x2oB:
10.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		4 / 7 SER B 299
VAL B 272
TRP B 302
PHE B 284
 None
 1.38A 6av7A-5x2oB:
undetectable
6av7B-5x2oB:
undetectable		 6av7A-5x2oB:
10.46
6av7B-5x2oB:
10.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		5 / 12 ILE B 145
VAL B  78
LEU B  40
PHE B  44
LEU B  98
 None
 1.10A 6b54A-5x2oB:
undetectable		 6b54A-5x2oB:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRZ_A_H8JA1206_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		5 / 12 THR B 319
GLY B 294
PHE B 284
VAL B 308
TYR B 309
 None
 1.05A 6drzA-5x2oB:
undetectable		 6drzA-5x2oB:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3
(Oryzias
latipes) 		5 / 12 VAL B 308
THR B 382
SER B 169
VAL B 277
TRP B 302
 None
 1.16A 6h7lB-5x2oB:
undetectable		 6h7lB-5x2oB:
9.39