SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5x33'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2201_1
(PROTEIN (METHIONINE
REPRESSOR))		 5x33 LTB4
RECEPTOR,LYSOZYME,LT
B4 RECEPTOR
(Cavia
porcellus;
Escherichia
virus
T4) 		4 / 4 HIS A 240
ALA A 188
PHE A 186
GLY A 191
 None
 1.35A 1mj2B-5x33A:
undetectable		 1mj2B-5x33A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC1200_1
(PROTEIN (METHIONINE
REPRESSOR))		 5x33 LTB4
RECEPTOR,LYSOZYME,LT
B4 RECEPTOR
(Cavia
porcellus;
Escherichia
virus
T4) 		4 / 4 HIS A 240
ALA A 188
PHE A 186
GLY A 191
 None
 1.37A 1mj2D-5x33A:
undetectable		 1mj2D-5x33A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_A_SAMA199_1
(METHIONINE REPRESSOR)		 5x33 LTB4
RECEPTOR,LYSOZYME,LT
B4 RECEPTOR
(Cavia
porcellus;
Escherichia
virus
T4) 		4 / 4 HIS A 240
ALA A 188
PHE A 186
GLY A 191
 None
 1.35A 1mjoB-5x33A:
undetectable		 1mjoB-5x33A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_D_SAMD200_1
(METHIONINE REPRESSOR)		 5x33 LTB4
RECEPTOR,LYSOZYME,LT
B4 RECEPTOR
(Cavia
porcellus;
Escherichia
virus
T4) 		4 / 4 HIS A 240
ALA A 188
PHE A 186
GLY A 191
 None
 1.34A 1mjoD-5x33A:
undetectable		 1mjoD-5x33A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_2
(DIHYDROFOLATE
REDUCTASE)		 5x33 LTB4
RECEPTOR,LYSOZYME,LT
B4 RECEPTOR
(Cavia
porcellus;
Escherichia
virus
T4) 		4 / 4 SER A 202
ILE A 206
VAL A 226
THR A  55
 None
 1.20A 1u70A-5x33A:
undetectable		 1u70A-5x33A:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 5x33 LTB4
RECEPTOR,LYSOZYME,LT
B4 RECEPTOR
(Cavia
porcellus;
Escherichia
virus
T4) 		5 / 12 LEU A  70
ASN A  38
LEU A  35
VAL A  29
LEU A 275
 None
 1.32A 2q7kA-5x33A:
undetectable		 2q7kA-5x33A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_2
(PROGESTERONE
RECEPTOR)		 5x33 LTB4
RECEPTOR,LYSOZYME,LT
B4 RECEPTOR
(Cavia
porcellus;
Escherichia
virus
T4) 		4 / 7 LEU A1133
ASN A1132
GLU A1128
MET A1102
 None
 1.18A 2w8yA-5x33A:
undetectable		 2w8yA-5x33A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		 5x33 LTB4
RECEPTOR,LYSOZYME,LT
B4 RECEPTOR
(Cavia
porcellus;
Escherichia
virus
T4) 		3 / 3 GLU A 187
GLY A 191
THR A 190
 None
 0.55A 3iazA-5x33A:
undetectable		 3iazA-5x33A:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 5x33 LTB4
RECEPTOR,LYSOZYME,LT
B4 RECEPTOR
(Cavia
porcellus;
Escherichia
virus
T4) 		4 / 6 TYR A 174
ASP A 243
VAL A 242
GLU A 187
 None
 1.06A 6djzB-5x33A:
undetectable		 6djzB-5x33A:
undetectable