SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5x47'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 5x47 3-DEHYDROQUINATE
DEHYDRATASE
(Acinetobacter
baumannii) 		6 / 12 ILE A  32
ARG A  61
VAL A 101
ALA A 137
ILE A  74
ILE A  73
 None
 1.41A 1epbB-5x47A:
undetectable		 1epbB-5x47A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_B_THAB2_1
(LIVER
CARBOXYLESTERASE I)		 5x47 3-DEHYDROQUINATE
DEHYDRATASE
(Acinetobacter
baumannii) 		5 / 11 LEU A 103
LEU A  27
LEU A  13
LEU A  16
HIS A   9
 None
 0.77A 1mx1B-5x47A:
undetectable		 1mx1B-5x47A:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2002_1
(SERUM ALBUMIN)		 5x47 3-DEHYDROQUINATE
DEHYDRATASE
(Acinetobacter
baumannii) 		5 / 11 ARG A  88
LEU A  91
ILE A  62
HIS A  63
GLY A  56
 None
 1.24A 2bxmA-5x47A:
undetectable		 2bxmA-5x47A:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A163_1
(BETA-LACTOGLOBULIN)		 5x47 3-DEHYDROQUINATE
DEHYDRATASE
(Acinetobacter
baumannii) 		5 / 12 ILE A  75
GLU A  68
ILE A   8
ILE A  58
ALA A  57
 None
 1.19A 2gj5A-5x47A:
undetectable		 2gj5A-5x47A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 5x47 3-DEHYDROQUINATE
DEHYDRATASE
(Acinetobacter
baumannii) 		4 / 6 LEU A  91
GLN A  51
ILE A   8
PHE A  98
 None
 1.13A 2jn3A-5x47A:
undetectable		 2jn3A-5x47A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5x47 3-DEHYDROQUINATE
DEHYDRATASE
(Acinetobacter
baumannii) 		3 / 3 ALA A 137
TYR A 140
PRO A  97
 None
 0.45A 4zdyA-5x47A:
undetectable		 4zdyA-5x47A:
15.53