SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5x5l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ERR_B_CCSB381_0 (ESTROGEN RECEPTOR)	5x5l	ADER (Acinetobacter baumannii)	3 / 3	GLU A 204 ALA A 202 SER A 200	GLU A 204 ( 0.6A) ALA A 202 ( 0.0A) SER A 200 ( 0.0A)	0.68A	1errB-5x5lA: undetectable	1errB-5x5lA: 16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QD3_A_5AEA201_1 (PEPTIDYL-TRNA HYDROLASE)	5x5l	ADER (Acinetobacter baumannii)	5 / 9	LEU A 192 GLY A 234 ASN A 229 VAL A 207 VAL A 211	LEU A 192 ( 0.6A) GLY A 234 ( 0.0A) ASN A 229 ( 0.6A) VAL A 207 ( 0.6A) VAL A 211 ( 0.6A)	0.98A	4qd3A-5x5lA: undetectable	4qd3A-5x5lA: 19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G48_B_1FLB1375_1 (DNA POLYMERASE III SUBUNIT BETA)	5x5l	ADER (Acinetobacter baumannii)	5 / 9	LEU A 192 LEU A 214 ILE A 176 LEU A 218 MET A 226	LEU A 192 ( 0.6A) LEU A 214 ( 0.6A) ILE A 176 ( 0.4A) LEU A 218 ( 0.6A) MET A 226 ( 0.0A)	1.26A	5g48B-5x5lA: undetectable	5g48B-5x5lA: 17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UC1_A_486A801_1 (GLUCOCORTICOID RECEPTOR)	5x5l	ADER (Acinetobacter baumannii)	5 / 12	LEU A 192 GLY A 234 VAL A 230 LEU A 227 ARG A 215	LEU A 192 ( 0.6A) GLY A 234 ( 0.0A) VAL A 230 ( 0.6A) LEU A 227 ( 0.6A) ARG A 215 ( 0.6A)	1.17A	5uc1A-5x5lA: undetectable	5uc1A-5x5lA: 16.24

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ERR_B_CCSB381_0","ESTROGEN RECEPTOR","5x5l","ADER","Acinetobacter baumannii",3,"GLU A 204;ALA A 202;SER A 200","GLU A 204 ( 0.6A);ALA A 202 ( 0.0A);SER A 200 ( 0.0A)","0.68A","1errB-5x5lA:undetectable","1errB-5x5lA:16.06"],["4QD3_A_5AEA201_1","PEPTIDYL-TRNA HYDROLASE","5x5l","ADER","Acinetobacter baumannii",5,"LEU A 192;GLY A 234;ASN A 229;VAL A 207;VAL A 211","LEU A 192 ( 0.6A);GLY A 234 ( 0.0A);ASN A 229 ( 0.6A);VAL A 207 ( 0.6A);VAL A 211 ( 0.6A)","0.98A","4qd3A-5x5lA:undetectable","4qd3A-5x5lA:19.59"],["5G48_B_1FLB1375_1","DNA POLYMERASE III SUBUNIT BETA","5x5l","ADER","Acinetobacter baumannii",5,"LEU A 192;LEU A 214;ILE A 176;LEU A 218;MET A 226","LEU A 192 ( 0.6A);LEU A 214 ( 0.6A);ILE A 176 ( 0.4A);LEU A 218 ( 0.6A);MET A 226 ( 0.0A)","1.26A","5g48B-5x5lA:undetectable","5g48B-5x5lA:17.44"],["5UC1_A_486A801_1","GLUCOCORTICOID RECEPTOR","5x5l","ADER","Acinetobacter baumannii",5,"LEU A 192;GLY A 234;VAL A 230;LEU A 227;ARG A 215","LEU A 192 ( 0.6A);GLY A 234 ( 0.0A);VAL A 230 ( 0.6A);LEU A 227 ( 0.6A);ARG A 215 ( 0.6A)","1.17A","5uc1A-5x5lA:undetectable","5uc1A-5x5lA:16.24"]]