SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5x5y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HZ4_A_BEZA784_0 (MALT REGULATORY PROTEIN)	5x5y	UNCHARACTERIZED PROTEIN (Pseudomonas aeruginosa)	4 / 6	LEU G 20 LEU G 64 PRO G 65 MET G 63	None	1.35A	1hz4A-5x5yG: undetectable	1hz4A-5x5yG: 22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T6Z_A_RBFA296_1 (RIBOFLAVIN KINASE/FMN ADENYLYLTRANSFERASE)	5x5y	PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER (Pseudomonas aeruginosa)	5 / 11	GLU B 124 GLU B 116 LYS B 115 LEU B 103 ILE B 99	None	1.50A	1t6zA-5x5yB: undetectable	1t6zA-5x5yB: 22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZLQ_A_ACTA1502_0 (NICKEL-BINDING PERIPLASMIC PROTEIN)	5x5y	UNCHARACTERIZED PROTEIN UNCHARACTERIZED PROTEIN (Pseudomonas aeruginosa; Pseudomonas aeruginosa)	4 / 5	PRO F 222 GLY G 170 ASN G 160 GLY G 139	None	1.16A	1zlqA-5x5yF: undetectable	1zlqA-5x5yF: 21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A3B_A_CFFA1434_1 (CHITINASE)	5x5y	UNCHARACTERIZED PROTEIN (Pseudomonas aeruginosa)	3 / 3	TRP G 149 THR G 172 TYR G 174	None	1.28A	2a3bA-5x5yG: undetectable	2a3bA-5x5yG: 23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AJV_L_COCL501_1 (ANTIBODY 7A1 FAB')	5x5y	UNCHARACTERIZED PROTEIN (Pseudomonas aeruginosa)	4 / 7	ALA G 161 TYR G 169 TYR G 255 TYR G 252	None	1.18A	2ajvH-5x5yG: undetectable 2ajvL-5x5yG: undetectable	2ajvH-5x5yG: 18.94 2ajvL-5x5yG: 20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BYO_A_LNLA1217_1 (LIPOPROTEIN LPPX)	5x5y	PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER (Pseudomonas aeruginosa)	4 / 4	VAL B 95 LEU B 183 ILE B 159 LEU B 83	None	0.90A	2byoA-5x5yB: undetectable	2byoA-5x5yB: 21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CDQ_A_SAMA1500_0 (ASPARTOKINASE)	5x5y	PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER (Pseudomonas aeruginosa)	4 / 8	ILE B 224 SER B 223 ASP B 220 LEU B 201	None	0.84A	2cdqA-5x5yB: undetectable	2cdqA-5x5yB: 18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HRE_B_CHDB701_0 (FERROCHELATASE)	5x5y	UNCHARACTERIZED PROTEIN (Pseudomonas aeruginosa)	3 / 3	LYS F 252 GLY F 58 PRO F 57	None	0.88A	2hreB-5x5yF: undetectable	2hreB-5x5yF: 21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OCF_A_ESTA596_1 (ESTROGEN RECEPTOR)	5x5y	UNCHARACTERIZED PROTEIN (Pseudomonas aeruginosa)	5 / 10	MET F 312 LEU F 309 ALA F 307 LEU F 304 LEU F 66	None	1.45A	2ocfA-5x5yF: undetectable	2ocfA-5x5yF: 21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V0M_D_KLND1498_1 (CYTOCHROME P450 3A4)	5x5y	UNCHARACTERIZED PROTEIN (Pseudomonas aeruginosa)	5 / 11	LEU F 350 ALA F 288 THR F 285 ARG F 97 LEU F 99	None	1.31A	2v0mD-5x5yF: undetectable	2v0mD-5x5yF: 21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VN1_A_FK5A501_1 (70 KDA PEPTIDYLPROLYL ISOMERASE)	5x5y	PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER (Pseudomonas aeruginosa)	5 / 11	PHE B 165 ASP B 194 PHE B 46 CYH B 204 ILE B 203	None	1.45A	2vn1A-5x5yB: undetectable	2vn1A-5x5yB: 22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W8Y_A_486A1000_1 (PROGESTERONE RECEPTOR)	5x5y	UNCHARACTERIZED PROTEIN (Pseudomonas aeruginosa)	5 / 12	LEU F 291 LEU F 74 GLY F 71 LEU F 310 VAL F 109	None	1.29A	2w8yA-5x5yF: undetectable	2w8yA-5x5yF: 21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YGO_A_PCFA1213_1 (WNT INHIBITORY FACTOR 1)	5x5y	UNCHARACTERIZED PROTEIN (Pseudomonas aeruginosa)	4 / 6	LEU F 68 ILE F 72 MET F 103 PRO F 105	None	1.07A	2ygoA-5x5yF: undetectable	2ygoA-5x5yF: 16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A35_A_RBFA191_1 (LUMAZINE PROTEIN)	5x5y	PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER (Pseudomonas aeruginosa)	5 / 12	LEU B 4 THR B 3 GLN B 7 ALA B 6 ASN B 66	None	1.03A	3a35A-5x5yB: undetectable	3a35A-5x5yB: 23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A35_B_RBFB191_1 (LUMAZINE PROTEIN)	5x5y	PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER (Pseudomonas aeruginosa)	5 / 12	LEU B 4 THR B 3 GLN B 7 ALA B 6 ASN B 66	None	0.99A	3a35B-5x5yB: undetectable	3a35B-5x5yB: 23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A3B_A_RBFA191_1 (LUMAZINE PROTEIN)	5x5y	PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER (Pseudomonas aeruginosa)	5 / 12	LEU B 4 THR B 3 GLN B 7 ALA B 6 ASN B 66	None	1.01A	3a3bA-5x5yB: undetectable	3a3bA-5x5yB: 23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IK6_B_HCZB262_1 (GLUTAMATE RECEPTOR 2)	5x5y	PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER (Pseudomonas aeruginosa)	5 / 10	ILE B 80 LYS B 157 GLY B 79 LEU B 4 SER B 28	None	1.35A	3ik6B-5x5yB: undetectable 3ik6E-5x5yB: undetectable	3ik6B-5x5yB: 22.30 3ik6E-5x5yB: 22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IK6_B_HCZB800_1 (GLUTAMATE RECEPTOR 2)	5x5y	PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER (Pseudomonas aeruginosa)	5 / 10	LEU B 4 SER B 28 ILE B 80 LYS B 157 GLY B 79	None	1.37A	3ik6B-5x5yB: undetectable 3ik6E-5x5yB: undetectable	3ik6B-5x5yB: 22.30 3ik6E-5x5yB: 22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OU6_C_SAMC300_1 (SAM-DEPENDENT METHYLTRANSFERASE)	5x5y	UNCHARACTERIZED PROTEIN UNCHARACTERIZED PROTEIN (Pseudomonas aeruginosa; Pseudomonas aeruginosa)	3 / 3	TYR F 216 GLY G 181 ASP G 177	None	0.67A	3ou6C-5x5yF: undetectable	3ou6C-5x5yF: 20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VW1_D_CVID301_1 (PUTATIVE REGULATORY PROTEIN)	5x5y	UNCHARACTERIZED PROTEIN (Pseudomonas aeruginosa)	3 / 3	TYR G 61 MET G 103 LEU G 278	None	1.01A	3vw1D-5x5yG: undetectable	3vw1D-5x5yG: 22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGZ_A_CQAA302_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE)	5x5y	PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER UNCHARACTERIZED PROTEIN (Pseudomonas aeruginosa; Pseudomonas aeruginosa)	4 / 7	GLU F 82 ARG B 150 GLY B 135 ARG B 91	None	1.03A	4fgzA-5x5yF: undetectable	4fgzA-5x5yF: 19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HXY_B_ACAB502_1 (PLM1)	5x5y	UNCHARACTERIZED PROTEIN (Pseudomonas aeruginosa)	4 / 7	GLN F 37 TYR F 34 LEU F 132 ASP F 136	None	0.81A	4hxyB-5x5yF: undetectable	4hxyB-5x5yF: 22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L8F_B_MTXB301_1 (GAMMA-GLUTAMYL HYDROLASE)	5x5y	UNCHARACTERIZED PROTEIN (Pseudomonas aeruginosa)	5 / 11	PHE G 187 GLY G 138 GLY G 139 ALA G 135 LEU G 134	None	1.16A	4l8fB-5x5yG: undetectable	4l8fB-5x5yG: 20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L8F_D_MTXD301_1 (GAMMA-GLUTAMYL HYDROLASE)	5x5y	UNCHARACTERIZED PROTEIN (Pseudomonas aeruginosa)	5 / 11	PHE G 187 GLY G 138 GLY G 139 ALA G 135 LEU G 134	None	1.18A	4l8fD-5x5yG: undetectable	4l8fD-5x5yG: 20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OJB_A_198A1001_1 (ANDROGEN RECEPTOR)	5x5y	UNCHARACTERIZED PROTEIN (Pseudomonas aeruginosa)	5 / 12	LEU G 285 LEU G 107 MET G 106 MET G 103 VAL G 102	None	1.42A	4ojbA-5x5yG: undetectable	4ojbA-5x5yG: 21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OKB_A_198A1002_1 (ANDROGEN RECEPTOR)	5x5y	UNCHARACTERIZED PROTEIN (Pseudomonas aeruginosa)	5 / 12	LEU G 285 LEU G 107 MET G 106 MET G 103 VAL G 102	None	1.41A	4okbA-5x5yG: 2.1	4okbA-5x5yG: 21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OKX_A_198A1002_1 (ANDROGEN RECEPTOR)	5x5y	UNCHARACTERIZED PROTEIN (Pseudomonas aeruginosa)	5 / 12	LEU G 285 LEU G 107 MET G 106 MET G 103 VAL G 102	None	1.41A	4okxA-5x5yG: undetectable	4okxA-5x5yG: 21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OLM_A_198A1001_1 (ANDROGEN RECEPTOR)	5x5y	UNCHARACTERIZED PROTEIN (Pseudomonas aeruginosa)	5 / 12	LEU G 285 LEU G 107 MET G 106 MET G 103 VAL G 102	None	1.38A	4olmA-5x5yG: undetectable	4olmA-5x5yG: 21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_A_BQ1A1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	5x5y	UNCHARACTERIZED PROTEIN (Pseudomonas aeruginosa)	3 / 3	GLU G 35 ALA G 48 PHE G 51	None	0.54A	4v1fA-5x5yG: undetectable	4v1fA-5x5yG: 15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_C_BQ1C1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	5x5y	UNCHARACTERIZED PROTEIN (Pseudomonas aeruginosa)	3 / 3	GLU G 35 ALA G 48 PHE G 51	None	0.53A	4v1fC-5x5yG: undetectable	4v1fC-5x5yG: 15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XUM_B_IMNB501_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	5x5y	PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER (Pseudomonas aeruginosa)	5 / 11	GLY B 79 SER B 154 ALA B 153 ILE B 102 LEU B 83	None	1.17A	4xumB-5x5yB: undetectable	4xumB-5x5yB: 23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B2S_A_ACTA107_0 (CRISPR-ASSOCIATED ENDONUCLEASE CAS9 GUIDE RNA)	5x5y	UNCHARACTERIZED PROTEIN (Pseudomonas aeruginosa)	3 / 3	VAL G 203 THR G 205 ARG G 173	None	0.51A	5b2sB-5x5yG: undetectable	5b2sB-5x5yG: 13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B2T_A_ACTA108_0 (CRISPR-ASSOCIATED ENDONUCLEASE CAS9 GUIDE RNA)	5x5y	UNCHARACTERIZED PROTEIN (Pseudomonas aeruginosa)	3 / 3	VAL G 203 THR G 205 ARG G 173	None	0.52A	5b2tB-5x5yG: 2.4	5b2tB-5x5yG: 12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DZK_Z_BEZZ801_0 (ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 BEZ-LEU-LEU)	5x5y	PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER (Pseudomonas aeruginosa)	4 / 4	ILE B 209 GLY B 33 ILE B 224 LEU B 34	None	0.84A	5dzkl-5x5yB: undetectable 5dzkz-5x5yB: undetectable	5dzkl-5x5yB: 23.48 5dzkz-5x5yB: 1.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HG0_A_SAMA301_0 (PANTOTHENATE SYNTHETASE)	5x5y	UNCHARACTERIZED PROTEIN (Pseudomonas aeruginosa)	5 / 12	GLY F 299 LEU F 81 GLN F 95 GLY F 77 LEU F 302	None	1.09A	5hg0A-5x5yF: undetectable	5hg0A-5x5yF: 21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JGL_A_SAMA301_0 (UBIE/COQ5 FAMILY METHYLTRANSFERASE, PUTATIVE)	5x5y	PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER (Pseudomonas aeruginosa)	5 / 12	ALA B 207 LEU B 34 LEU B 215 ALA B 221 GLY B 219	None	1.40A	5jglA-5x5yB: 2.2	5jglA-5x5yB: 20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JH7_B_6K9B503_0 (TUBULIN BETA-2B CHAIN)	5x5y	PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER (Pseudomonas aeruginosa)	5 / 11	VAL B 197 ASP B 194 THR B 193 TYR B 234 LEU B 235	None	1.11A	5jh7B-5x5yB: undetectable	5jh7B-5x5yB: 20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JH7_D_6K9D502_0 (TUBULIN BETA-2B CHAIN)	5x5y	PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER (Pseudomonas aeruginosa)	5 / 11	VAL B 197 ASP B 194 THR B 193 TYR B 234 LEU B 235	None	1.10A	5jh7D-5x5yB: undetectable	5jh7D-5x5yB: 20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V5Z_A_1YNA602_2 (LANOSTEROL 14-ALPHA DEMETHYLASE)	5x5y	UNCHARACTERIZED PROTEIN (Pseudomonas aeruginosa)	3 / 3	GLY G 248 THR G 55 PRO G 122	None	0.58A	5v5zA-5x5yG: 1.2	5v5zA-5x5yG: 21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZJI_A_PQNA844_1 (PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1 PHOTOSYSTEM I REACTION CENTER SUBUNIT IX)	5x5y	PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER (Pseudomonas aeruginosa)	5 / 10	PHE B 125 GLY B 120 ILE B 102 ALA B 153 LEU B 152	None	1.20A	5zjiA-5x5yB: undetectable 5zjiJ-5x5yB: undetectable	5zjiA-5x5yB: 14.04 5zjiJ-5x5yB: 11.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6B89_A_NOVA403_1 (LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB)	5x5y	PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER (Pseudomonas aeruginosa)	5 / 10	ALA B 76 TYR B 82 PRO B 84 PHE B 90 ARG B 150	None	0.86A	6b89A-5x5yB: 31.7	6b89A-5x5yB: 63.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6B89_A_NOVA403_1 (LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB)	5x5y	PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER (Pseudomonas aeruginosa)	5 / 10	ALA B 76 TYR B 82 PRO B 84 SER B 88 PHE B 90	None	0.91A	6b89A-5x5yB: 31.7	6b89A-5x5yB: 63.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6B89_B_NOVB403_2 (LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB)	5x5y	PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER (Pseudomonas aeruginosa)	5 / 10	ALA B 76 TYR B 82 PRO B 84 PHE B 90 ARG B 150	None	0.77A	6b89B-5x5yB: 30.7	6b89B-5x5yB: 63.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6B89_B_NOVB403_2 (LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB)	5x5y	PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER (Pseudomonas aeruginosa)	5 / 10	ALA B 76 TYR B 82 PRO B 84 SER B 88 PHE B 90	None	0.82A	6b89B-5x5yB: 30.7	6b89B-5x5yB: 63.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6B89_B_NOVB403_2 (LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB)	5x5y	PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER (Pseudomonas aeruginosa)	5 / 10	TYR B 82 PRO B 84 GLU B 86 PHE B 90 ARG B 150	None	1.03A	6b89B-5x5yB: 30.7	6b89B-5x5yB: 63.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GTQ_A_ACTA204_0 (N-ACETYLTRANSFERASE)	5x5y	PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER (Pseudomonas aeruginosa)	4 / 5	LEU B 201 CYH B 204 THR B 206 GLY B 219	None	1.22A	6gtqA-5x5yB: undetectable	6gtqA-5x5yB: 19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HZP_A_FVTA501_0 (PEPTIDE ABC TRANSPORTER PERMEASE)	5x5y	UNCHARACTERIZED PROTEIN (Pseudomonas aeruginosa)	4 / 8	VAL F 254 GLN F 61 PRO F 122 ILE F 125	None	0.78A	6hzpA-5x5yF: 2.7	6hzpA-5x5yF: 23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MN5_D_LLLD301_0 (AMINOGLYCOSIDE N(3)-ACETYLTRANSFERA SE, AAC(3)-IVA)	5x5y	UNCHARACTERIZED PROTEIN (Pseudomonas aeruginosa)	4 / 6	ASP G 47 ARG G 132 GLU G 35 GLU G 125	None	1.36A	6mn5D-5x5yG: undetectable	6mn5D-5x5yG: 12.68

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1HZ4_A_BEZA784_0","MALT REGULATORY PROTEIN","5x5y","UNCHARACTERIZED PROTEIN","Pseudomonas aeruginosa",4,"LEU G  20;LEU G  64;PRO G  65;MET G  63","None","1.35A","1hz4A-5x5yG:undetectable","1hz4A-5x5yG:22.63"],["1T6Z_A_RBFA296_1","RIBOFLAVIN KINASE\/FMN ADENYLYLTRANSFERASE","5x5y","PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER","Pseudomonas aeruginosa",5,"GLU B 124;GLU B 116;LYS B 115;LEU B 103;ILE B  99","None","1.50A","1t6zA-5x5yB:undetectable","1t6zA-5x5yB:22.59"],["1ZLQ_A_ACTA1502_0","NICKEL-BINDING PERIPLASMIC PROTEIN","5x5y","UNCHARACTERIZED PROTEIN;UNCHARACTERIZED PROTEIN","Pseudomonas aeruginosa;Pseudomonas aeruginosa",4,"PRO F 222;GLY G 170;ASN G 160;GLY G 139","None","1.16A","1zlqA-5x5yF:undetectable","1zlqA-5x5yF:21.64"],["2A3B_A_CFFA1434_1","CHITINASE","5x5y","UNCHARACTERIZED PROTEIN","Pseudomonas aeruginosa",3,"TRP G 149;THR G 172;TYR G 174","None","1.28A","2a3bA-5x5yG:undetectable","2a3bA-5x5yG:23.13"],["2AJV_L_COCL501_1","ANTIBODY 7A1 FAB';ANTIBODY 7A1 FAB'","5x5y","UNCHARACTERIZED PROTEIN","Pseudomonas aeruginosa",4,"ALA G 161;TYR G 169;TYR G 255;TYR G 252","None","1.18A","2ajvH-5x5yG:undetectable;2ajvL-5x5yG:undetectable","2ajvH-5x5yG:18.94;2ajvL-5x5yG:20.22"],["2BYO_A_LNLA1217_1","LIPOPROTEIN LPPX","5x5y","PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER","Pseudomonas aeruginosa",4,"VAL B  95;LEU B 183;ILE B 159;LEU B  83","None","0.90A","2byoA-5x5yB:undetectable","2byoA-5x5yB:21.85"],["2CDQ_A_SAMA1500_0","ASPARTOKINASE","5x5y","PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER","Pseudomonas aeruginosa",4,"ILE B 224;SER B 223;ASP B 220;LEU B 201","None","0.84A","2cdqA-5x5yB:undetectable","2cdqA-5x5yB:18.09"],["2HRE_B_CHDB701_0","FERROCHELATASE","5x5y","UNCHARACTERIZED PROTEIN","Pseudomonas aeruginosa",3,"LYS F 252;GLY F  58;PRO F  57","None","0.88A","2hreB-5x5yF:undetectable","2hreB-5x5yF:21.05"],["2OCF_A_ESTA596_1","ESTROGEN RECEPTOR","5x5y","UNCHARACTERIZED PROTEIN","Pseudomonas aeruginosa",5,"MET F 312;LEU F 309;ALA F 307;LEU F 304;LEU F  66","None","1.45A","2ocfA-5x5yF:undetectable","2ocfA-5x5yF:21.74"],["2V0M_D_KLND1498_1","CYTOCHROME P450 3A4","5x5y","UNCHARACTERIZED PROTEIN","Pseudomonas aeruginosa",5,"LEU F 350;ALA F 288;THR F 285;ARG F  97;LEU F  99","None","1.31A","2v0mD-5x5yF:undetectable","2v0mD-5x5yF:21.34"],["2VN1_A_FK5A501_1","70 KDA PEPTIDYLPROLYL ISOMERASE","5x5y","PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER","Pseudomonas aeruginosa",5,"PHE B 165;ASP B 194;PHE B  46;CYH B 204;ILE B 203","None","1.45A","2vn1A-5x5yB:undetectable","2vn1A-5x5yB:22.67"],["2W8Y_A_486A1000_1","PROGESTERONE RECEPTOR","5x5y","UNCHARACTERIZED PROTEIN","Pseudomonas aeruginosa",5,"LEU F 291;LEU F  74;GLY F  71;LEU F 310;VAL F 109","None","1.29A","2w8yA-5x5yF:undetectable","2w8yA-5x5yF:21.95"],["2YGO_A_PCFA1213_1","WNT INHIBITORY FACTOR 1","5x5y","UNCHARACTERIZED PROTEIN","Pseudomonas aeruginosa",4,"LEU F  68;ILE F  72;MET F 103;PRO F 105","None","1.07A","2ygoA-5x5yF:undetectable","2ygoA-5x5yF:16.85"],["3A35_A_RBFA191_1","LUMAZINE PROTEIN","5x5y","PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER","Pseudomonas aeruginosa",5,"LEU B   4;THR B   3;GLN B   7;ALA B   6;ASN B  66","None","1.03A","3a35A-5x5yB:undetectable","3a35A-5x5yB:23.35"],["3A35_B_RBFB191_1","LUMAZINE PROTEIN","5x5y","PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER","Pseudomonas aeruginosa",5,"LEU B   4;THR B   3;GLN B   7;ALA B   6;ASN B  66","None","0.99A","3a35B-5x5yB:undetectable","3a35B-5x5yB:23.35"],["3A3B_A_RBFA191_1","LUMAZINE PROTEIN","5x5y","PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER","Pseudomonas aeruginosa",5,"LEU B   4;THR B   3;GLN B   7;ALA B   6;ASN B  66","None","1.01A","3a3bA-5x5yB:undetectable","3a3bA-5x5yB:23.35"],["3IK6_B_HCZB262_1","GLUTAMATE RECEPTOR 2;GLUTAMATE RECEPTOR 2","5x5y","PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER","Pseudomonas aeruginosa",5,"ILE B  80;LYS B 157;GLY B  79;LEU B   4;SER B  28","None","1.35A","3ik6B-5x5yB:undetectable;3ik6E-5x5yB:undetectable","3ik6B-5x5yB:22.30;3ik6E-5x5yB:22.30"],["3IK6_B_HCZB800_1","GLUTAMATE RECEPTOR 2;GLUTAMATE RECEPTOR 2","5x5y","PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER","Pseudomonas aeruginosa",5,"LEU B   4;SER B  28;ILE B  80;LYS B 157;GLY B  79","None","1.37A","3ik6B-5x5yB:undetectable;3ik6E-5x5yB:undetectable","3ik6B-5x5yB:22.30;3ik6E-5x5yB:22.30"],["3OU6_C_SAMC300_1","SAM-DEPENDENT METHYLTRANSFERASE","5x5y","UNCHARACTERIZED PROTEIN;UNCHARACTERIZED PROTEIN","Pseudomonas aeruginosa;Pseudomonas aeruginosa",3,"TYR F 216;GLY G 181;ASP G 177","None","0.67A","3ou6C-5x5yF:undetectable","3ou6C-5x5yF:20.61"],["3VW1_D_CVID301_1","PUTATIVE REGULATORY PROTEIN","5x5y","UNCHARACTERIZED PROTEIN","Pseudomonas aeruginosa",3,"TYR G  61;MET G 103;LEU G 278","None","1.01A","3vw1D-5x5yG:undetectable","3vw1D-5x5yG:22.01"],["4FGZ_A_CQAA302_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE","5x5y","PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER;UNCHARACTERIZED PROTEIN","Pseudomonas aeruginosa;Pseudomonas aeruginosa",4,"GLU F  82;ARG B 150;GLY B 135;ARG B  91","None","1.03A","4fgzA-5x5yF:undetectable","4fgzA-5x5yF:19.67"],["4HXY_B_ACAB502_1","PLM1","5x5y","UNCHARACTERIZED PROTEIN","Pseudomonas aeruginosa",4,"GLN F  37;TYR F  34;LEU F 132;ASP F 136","None","0.81A","4hxyB-5x5yF:undetectable","4hxyB-5x5yF:22.08"],["4L8F_B_MTXB301_1","GAMMA-GLUTAMYL HYDROLASE","5x5y","UNCHARACTERIZED PROTEIN","Pseudomonas aeruginosa",5,"PHE G 187;GLY G 138;GLY G 139;ALA G 135;LEU G 134","None","1.16A","4l8fB-5x5yG:undetectable","4l8fB-5x5yG:20.81"],["4L8F_D_MTXD301_1","GAMMA-GLUTAMYL HYDROLASE","5x5y","UNCHARACTERIZED PROTEIN","Pseudomonas aeruginosa",5,"PHE G 187;GLY G 138;GLY G 139;ALA G 135;LEU G 134","None","1.18A","4l8fD-5x5yG:undetectable","4l8fD-5x5yG:20.81"],["4OJB_A_198A1001_1","ANDROGEN RECEPTOR","5x5y","UNCHARACTERIZED PROTEIN","Pseudomonas aeruginosa",5,"LEU G 285;LEU G 107;MET G 106;MET G 103;VAL G 102","None","1.42A","4ojbA-5x5yG:undetectable","4ojbA-5x5yG:21.62"],["4OKB_A_198A1002_1","ANDROGEN RECEPTOR","5x5y","UNCHARACTERIZED PROTEIN","Pseudomonas aeruginosa",5,"LEU G 285;LEU G 107;MET G 106;MET G 103;VAL G 102","None","1.41A","4okbA-5x5yG:2.1","4okbA-5x5yG:21.62"],["4OKX_A_198A1002_1","ANDROGEN RECEPTOR","5x5y","UNCHARACTERIZED PROTEIN","Pseudomonas aeruginosa",5,"LEU G 285;LEU G 107;MET G 106;MET G 103;VAL G 102","None","1.41A","4okxA-5x5yG:undetectable","4okxA-5x5yG:21.62"],["4OLM_A_198A1001_1","ANDROGEN RECEPTOR","5x5y","UNCHARACTERIZED PROTEIN","Pseudomonas aeruginosa",5,"LEU G 285;LEU G 107;MET G 106;MET G 103;VAL G 102","None","1.38A","4olmA-5x5yG:undetectable","4olmA-5x5yG:21.62"],["4V1F_A_BQ1A1087_0","F0F1 ATP SYNTHASE SUBUNIT C","5x5y","UNCHARACTERIZED PROTEIN","Pseudomonas aeruginosa",3,"GLU G  35;ALA G  48;PHE G  51","None","0.54A","4v1fA-5x5yG:undetectable","4v1fA-5x5yG:15.58"],["4V1F_C_BQ1C1087_0","F0F1 ATP SYNTHASE SUBUNIT C","5x5y","UNCHARACTERIZED PROTEIN","Pseudomonas aeruginosa",3,"GLU G  35;ALA G  48;PHE G  51","None","0.53A","4v1fC-5x5yG:undetectable","4v1fC-5x5yG:15.58"],["4XUM_B_IMNB501_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","5x5y","PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER","Pseudomonas aeruginosa",5,"GLY B  79;SER B 154;ALA B 153;ILE B 102;LEU B  83","None","1.17A","4xumB-5x5yB:undetectable","4xumB-5x5yB:23.91"],["5B2S_A_ACTA107_0","CRISPR-ASSOCIATED ENDONUCLEASE CAS9;GUIDE RNA","5x5y","UNCHARACTERIZED PROTEIN","Pseudomonas aeruginosa",3,"VAL G 203;THR G 205;ARG G 173","None","0.51A","5b2sB-5x5yG:undetectable","5b2sB-5x5yG:13.16"],["5B2T_A_ACTA108_0","CRISPR-ASSOCIATED ENDONUCLEASE CAS9;GUIDE RNA","5x5y","UNCHARACTERIZED PROTEIN","Pseudomonas aeruginosa",3,"VAL G 203;THR G 205;ARG G 173","None","0.52A","5b2tB-5x5yG:2.4","5b2tB-5x5yG:12.94"],["5DZK_Z_BEZZ801_0","ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1;BEZ-LEU-LEU","5x5y","PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER","Pseudomonas aeruginosa",4,"ILE B 209;GLY B  33;ILE B 224;LEU B  34","None","0.84A","5dzkl-5x5yB:undetectable;5dzkz-5x5yB:undetectable","5dzkl-5x5yB:23.48;5dzkz-5x5yB:1.64"],["5HG0_A_SAMA301_0","PANTOTHENATE SYNTHETASE","5x5y","UNCHARACTERIZED PROTEIN","Pseudomonas aeruginosa",5,"GLY F 299;LEU F  81;GLN F  95;GLY F  77;LEU F 302","None","1.09A","5hg0A-5x5yF:undetectable","5hg0A-5x5yF:21.33"],["5JGL_A_SAMA301_0","UBIE\/COQ5 FAMILY METHYLTRANSFERASE, PUTATIVE","5x5y","PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER","Pseudomonas aeruginosa",5,"ALA B 207;LEU B  34;LEU B 215;ALA B 221;GLY B 219","None","1.40A","5jglA-5x5yB:2.2","5jglA-5x5yB:20.39"],["5JH7_B_6K9B503_0","TUBULIN BETA-2B CHAIN","5x5y","PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER","Pseudomonas aeruginosa",5,"VAL B 197;ASP B 194;THR B 193;TYR B 234;LEU B 235","None","1.11A","5jh7B-5x5yB:undetectable","5jh7B-5x5yB:20.31"],["5JH7_D_6K9D502_0","TUBULIN BETA-2B CHAIN","5x5y","PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER","Pseudomonas aeruginosa",5,"VAL B 197;ASP B 194;THR B 193;TYR B 234;LEU B 235","None","1.10A","5jh7D-5x5yB:undetectable","5jh7D-5x5yB:20.31"],["5V5Z_A_1YNA602_2","LANOSTEROL 14-ALPHA DEMETHYLASE","5x5y","UNCHARACTERIZED PROTEIN","Pseudomonas aeruginosa",3,"GLY G 248;THR G  55;PRO G 122","None","0.58A","5v5zA-5x5yG:1.2","5v5zA-5x5yG:21.96"],["5ZJI_A_PQNA844_1","PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1;PHOTOSYSTEM I REACTION CENTER SUBUNIT IX","5x5y","PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER","Pseudomonas aeruginosa",5,"PHE B 125;GLY B 120;ILE B 102;ALA B 153;LEU B 152","None","1.20A","5zjiA-5x5yB:undetectable;5zjiJ-5x5yB:undetectable","5zjiA-5x5yB:14.04;5zjiJ-5x5yB:11.72"],["6B89_A_NOVA403_1","LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB","5x5y","PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER","Pseudomonas aeruginosa",5,"ALA B  76;TYR B  82;PRO B  84;PHE B  90;ARG B 150","None","0.86A","6b89A-5x5yB:31.7","6b89A-5x5yB:63.75"],["6B89_A_NOVA403_1","LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB","5x5y","PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER","Pseudomonas aeruginosa",5,"ALA B  76;TYR B  82;PRO B  84;SER B  88;PHE B  90","None","0.91A","6b89A-5x5yB:31.7","6b89A-5x5yB:63.75"],["6B89_B_NOVB403_2","LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB","5x5y","PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER","Pseudomonas aeruginosa",5,"ALA B  76;TYR B  82;PRO B  84;PHE B  90;ARG B 150","None","0.77A","6b89B-5x5yB:30.7","6b89B-5x5yB:63.75"],["6B89_B_NOVB403_2","LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB","5x5y","PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER","Pseudomonas aeruginosa",5,"ALA B  76;TYR B  82;PRO B  84;SER B  88;PHE B  90","None","0.82A","6b89B-5x5yB:30.7","6b89B-5x5yB:63.75"],["6B89_B_NOVB403_2","LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB","5x5y","PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER","Pseudomonas aeruginosa",5,"TYR B  82;PRO B  84;GLU B  86;PHE B  90;ARG B 150","None","1.03A","6b89B-5x5yB:30.7","6b89B-5x5yB:63.75"],["6GTQ_A_ACTA204_0","N-ACETYLTRANSFERASE","5x5y","PROBABLE ATP-BINDING COMPONENT OF ABC TRANSPORTER","Pseudomonas aeruginosa",4,"LEU B 201;CYH B 204;THR B 206;GLY B 219","None","1.22A","6gtqA-5x5yB:undetectable","6gtqA-5x5yB:19.31"],["6HZP_A_FVTA501_0","PEPTIDE ABC TRANSPORTER PERMEASE","5x5y","UNCHARACTERIZED PROTEIN","Pseudomonas aeruginosa",4,"VAL F 254;GLN F  61;PRO F 122;ILE F 125","None","0.78A","6hzpA-5x5yF:2.7","6hzpA-5x5yF:23.72"],["6MN5_D_LLLD301_0","AMINOGLYCOSIDE N(3)-ACETYLTRANSFERASE, AAC(3)-IVA","5x5y","UNCHARACTERIZED PROTEIN","Pseudomonas aeruginosa",4,"ASP G  47;ARG G 132;GLU G  35;GLU G 125","None","1.36A","6mn5D-5x5yG:undetectable","6mn5D-5x5yG:12.68"]]