SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5x6a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K5Q_B_PACB559_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 5x6a ENDOGLUCANASE,
PUTATIVE
(Aspergillus
fumigatus) 		4 / 7 SER A  85
PRO A  83
ALA A 162
TYR A 175
 None
 1.02A 1k5qA-5x6aA:
undetectable
1k5qB-5x6aA:
undetectable		 1k5qA-5x6aA:
undetectable
1k5qB-5x6aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5x6a ENDOGLUCANASE,
PUTATIVE
(Aspergillus
fumigatus) 		4 / 7 GLN A  21
TYR A  22
TYR A  13
ILE A   7
 None
 1.14A 2ph9A-5x6aA:
undetectable
2ph9B-5x6aA:
undetectable		 2ph9A-5x6aA:
16.74
2ph9B-5x6aA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 5x6a ENDOGLUCANASE,
PUTATIVE
(Aspergillus
fumigatus) 		5 / 11 GLY A 193
GLY A 191
ALA A  95
ALA A 195
ALA A 225
 None
 1.03A 3g88A-5x6aA:
undetectable		 3g88A-5x6aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 5x6a ENDOGLUCANASE,
PUTATIVE
(Aspergillus
fumigatus) 		5 / 11 GLY A 193
GLY A 191
ALA A  95
ALA A 195
ALA A 225
 None
 1.03A 3g88B-5x6aA:
undetectable		 3g88B-5x6aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 5x6a ENDOGLUCANASE,
PUTATIVE
(Aspergillus
fumigatus) 		5 / 12 GLY A 193
GLY A 191
ALA A  95
ALA A 195
ALA A 225
 None
 1.01A 3g89A-5x6aA:
undetectable		 3g89A-5x6aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 5x6a ENDOGLUCANASE,
PUTATIVE
(Aspergillus
fumigatus) 		5 / 11 GLY A 193
GLY A 191
ALA A  95
ALA A 195
ALA A 225
 None
 1.01A 3g89B-5x6aA:
undetectable		 3g89B-5x6aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 5x6a ENDOGLUCANASE,
PUTATIVE
(Aspergillus
fumigatus) 		5 / 12 GLY A 193
GLY A 191
ALA A  95
ALA A 195
ALA A 225
 None
 1.04A 3g8bA-5x6aA:
undetectable		 3g8bA-5x6aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 5x6a ENDOGLUCANASE,
PUTATIVE
(Aspergillus
fumigatus) 		5 / 12 GLY A 193
GLY A 191
ALA A  95
ALA A 195
ALA A 225
 None
 1.04A 3g8bB-5x6aA:
undetectable		 3g8bB-5x6aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 5x6a ENDOGLUCANASE,
PUTATIVE
(Aspergillus
fumigatus) 		3 / 3 ARG A  58
ASP A  45
ASP A  53
 None
 0.68A 3jayA-5x6aA:
undetectable		 3jayA-5x6aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 5x6a ENDOGLUCANASE,
PUTATIVE
(Aspergillus
fumigatus) 		3 / 3 ARG A  58
ASP A  45
ASP A  53
 None
 0.62A 3jb2A-5x6aA:
undetectable		 3jb2A-5x6aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 5x6a ENDOGLUCANASE,
PUTATIVE
(Aspergillus
fumigatus) 		3 / 3 ARG A  58
ASP A  45
ASP A  53
 None
 0.50A 3jb3A-5x6aA:
undetectable		 3jb3A-5x6aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2V_A_RLTA397_1
(INTEGRASE)		 5x6a ENDOGLUCANASE,
PUTATIVE
(Aspergillus
fumigatus) 		4 / 7 GLN A 173
PRO A 176
GLN A 177
GLU A 159
 None
 1.10A 3l2vA-5x6aA:
undetectable		 3l2vA-5x6aA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3M_A_DLUA398_1
(PFV INTEGRASE)		 5x6a ENDOGLUCANASE,
PUTATIVE
(Aspergillus
fumigatus) 		4 / 8 GLY A  46
PRO A 176
GLN A 177
GLU A 159
 None
 0.96A 3s3mA-5x6aA:
undetectable		 3s3mA-5x6aA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3N_A_DLUA398_1
(PFV INTEGRASE)		 5x6a ENDOGLUCANASE,
PUTATIVE
(Aspergillus
fumigatus) 		4 / 8 GLY A  46
PRO A 176
GLN A 177
GLU A 159
 None
 0.97A 3s3nA-5x6aA:
undetectable		 3s3nA-5x6aA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 5x6a ENDOGLUCANASE,
PUTATIVE
(Aspergillus
fumigatus) 		5 / 12 THR A  80
GLY A  16
GLY A   6
TRP A  79
ALA A  60
 None
 0.97A 4uciA-5x6aA:
undetectable		 4uciA-5x6aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 5x6a ENDOGLUCANASE,
PUTATIVE
(Aspergillus
fumigatus) 		5 / 12 THR A  80
GLY A  16
GLY A   6
TRP A  79
ALA A  60
 None
 0.98A 4uciB-5x6aA:
undetectable		 4uciB-5x6aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 5x6a ENDOGLUCANASE,
PUTATIVE
(Aspergillus
fumigatus) 		5 / 12 THR A  80
GLY A  16
GLY A   6
TRP A  79
ALA A  60
 None
 1.00A 4uckB-5x6aA:
undetectable		 4uckB-5x6aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5x6a ENDOGLUCANASE,
PUTATIVE
(Aspergillus
fumigatus) 		3 / 3 TYR A 154
ALA A 189
TYR A 149
 None
 0.84A 5uunB-5x6aA:
undetectable		 5uunB-5x6aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWO_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5x6a ENDOGLUCANASE,
PUTATIVE
(Aspergillus
fumigatus) 		5 / 9 TYR A 219
ALA A 116
ILE A  91
GLY A 206
GLY A 118
 None
 1.22A 6awoA-5x6aA:
undetectable		 6awoA-5x6aA:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWQ_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5x6a ENDOGLUCANASE,
PUTATIVE
(Aspergillus
fumigatus) 		5 / 9 TYR A 219
ALA A 116
ILE A  91
GLY A 206
GLY A 118
 None
 1.22A 6awqA-5x6aA:
undetectable		 6awqA-5x6aA:
10.78