SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5x6x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_1
(HIV-II PROTEASE)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		5 / 12 GLY C 429
ALA C 430
GLY C 243
ILE C 435
ILE C 433
 None
 0.77A 1hshC-5x6xC:
undetectable		 1hshC-5x6xC:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		5 / 12 GLY C 789
ALA C 709
SER C 784
HIS C 783
LEU C 779
 None
 1.18A 1kiaD-5x6xC:
7.7		 1kiaD-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		5 / 12 VAL C 609
LEU C 500
ALA C 567
LEU C 564
ALA C 506
 None
 1.03A 1sa1A-5x6xC:
undetectable
1sa1B-5x6xC:
undetectable		 1sa1A-5x6xC:
14.07
1sa1B-5x6xC:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		5 / 12 VAL C 609
LEU C 500
ALA C 567
LEU C 564
ALA C 506
 None
 1.05A 1sa1C-5x6xC:
undetectable
1sa1D-5x6xC:
undetectable		 1sa1C-5x6xC:
14.07
1sa1D-5x6xC:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SKX_A_RFPA1_2
(ORPHAN NUCLEAR
RECEPTOR PXR)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 5 PHE C 461
LEU C 233
MET C 465
LEU C 406
 None
 1.26A 1skxA-5x6xC:
undetectable		 1skxA-5x6xC:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_1
(SUN PROTEIN)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		3 / 3 PRO C 290
ASP C 308
ASP C 359
 None
 0.38A 1sqfA-5x6xC:
4.0		 1sqfA-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 7 LEU C 779
HIS C 704
THR C 630
TRP C 722
 None
None
EDO  C 901 (-4.0A)
None
 1.20A 1v55C-5x6xC:
undetectable
1v55N-5x6xC:
undetectable
1v55P-5x6xC:
undetectable		 1v55C-5x6xC:
undetectable
1v55N-5x6xC:
undetectable
1v55P-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		6 / 12 LEU C 269
TYR C 285
ILE C 286
GLY C 287
PRO C 290
HIS C 293
 None
 0.66A 1vptA-5x6xC:
12.4		 1vptA-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W0G_A_MYTA1499_1
(CYTOCHROME P450 3A4)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 6 SER C 207
ILE C 229
ALA C 472
ALA C 506
 None
 0.67A 1w0gA-5x6xC:
undetectable		 1w0gA-5x6xC:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		3 / 3 LYS C 231
ASP C 556
ASN C 494
 None
 1.01A 2bm9A-5x6xC:
6.7		 2bm9A-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		5 / 12 ILE C  26
LEU C  84
CYH C  27
LEU C 531
PHE C 629
 None
 1.24A 2jn3A-5x6xC:
undetectable		 2jn3A-5x6xC:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 8 LEU C 779
HIS C 704
THR C 630
TRP C 722
 None
None
EDO  C 901 (-4.0A)
None
 1.20A 2y69C-5x6xC:
undetectable
2y69N-5x6xC:
undetectable
2y69P-5x6xC:
undetectable		 2y69C-5x6xC:
undetectable
2y69N-5x6xC:
undetectable
2y69P-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 8 HIS C 704
THR C 630
TRP C 722
LEU C 779
 None
EDO  C 901 (-4.0A)
None
None
 1.19A 3abmA-5x6xC:
undetectable
3abmC-5x6xC:
undetectable
3abmP-5x6xC:
undetectable		 3abmA-5x6xC:
undetectable
3abmC-5x6xC:
undetectable
3abmP-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 8 HIS C 704
THR C 630
TRP C 722
LEU C 779
 None
EDO  C 901 (-4.0A)
None
None
 1.22A 3asoA-5x6xC:
undetectable
3asoC-5x6xC:
undetectable
3asoP-5x6xC:
undetectable		 3asoA-5x6xC:
undetectable
3asoC-5x6xC:
undetectable
3asoP-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 8 LEU C 779
HIS C 704
THR C 630
TRP C 722
 None
None
EDO  C 901 (-4.0A)
None
 1.20A 3asoC-5x6xC:
undetectable
3asoN-5x6xC:
undetectable
3asoP-5x6xC:
undetectable		 3asoC-5x6xC:
undetectable
3asoN-5x6xC:
undetectable
3asoP-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DXY_A_SAMA1_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		5 / 11 GLY C 210
ILE C 229
GLU C 230
ASP C 471
ALA C 472
 None
 0.60A 3dxyA-5x6xC:
4.2		 3dxyA-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_D_LOCD700_2
(TUBULIN BETA-2B
CHAIN)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		5 / 11 LEU C 473
LEU C 477
LEU C 503
ASN C 507
VAL C 483
 None
 1.21A 3e22D-5x6xC:
undetectable		 3e22D-5x6xC:
11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FUU_A_ADNA0_1
(DIMETHYLADENOSINE
TRANSFERASE)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		5 / 12 VAL C 209
GLY C 210
GLU C 230
ASP C 471
ALA C 472
 None
 0.53A 3fuuA-5x6xC:
7.6		 3fuuA-5x6xC:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		5 / 12 THR C 279
HIS C 463
LEU C 272
ILE C 357
TYR C 211
 None
 1.37A 3gwxB-5x6xC:
undetectable		 3gwxB-5x6xC:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_C_MTXC164_2
(DIHYDROFOLATE
REDUCTASE)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 4 ILE C 304
ARG C 422
ILE C 283
THR C 323
 None
 1.15A 3ia4C-5x6xC:
undetectable		 3ia4C-5x6xC:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID6_C_SAMC301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		5 / 12 GLY C 210
GLU C 230
SER C 232
ASP C 471
ALA C 472
 None
 0.92A 3id6C-5x6xC:
7.4		 3id6C-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_2
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT
LIGHT CHAIN OF
ANTIBODY FAB
FRAGMENT)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 5 TYR C 603
GLN C 561
ILE C 788
LEU C 791
 None
 1.19A 3ls4L-5x6xC:
undetectable		 3ls4L-5x6xC:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_F_SAMF228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		5 / 12 GLY C 210
GLU C 230
SER C 232
ASP C 471
ALA C 472
 None
 0.93A 3nmuA-5x6xC:
undetectable
3nmuF-5x6xC:
6.3		 3nmuA-5x6xC:
undetectable
3nmuF-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_B_RBVB601_1
(RNA POLYMERASE)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		5 / 9 ASN C 507
TYR C 565
GLY C 568
ASP C 566
LEU C 797
 None
 1.43A 3sfuB-5x6xC:
undetectable		 3sfuB-5x6xC:
9.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_A_CYZA266_2
(GLUTAMATE RECEPTOR 2)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 5 ILE C 229
SER C 232
LYS C 231
GLY C 470
 None
 1.07A 3tkdB-5x6xC:
undetectable		 3tkdB-5x6xC:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_B_CYZB267_1
(GLUTAMATE RECEPTOR 2)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 5 ILE C 229
SER C 232
LYS C 231
GLY C 470
 None
 1.06A 3tkdA-5x6xC:
undetectable		 3tkdA-5x6xC:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_H_CLMH221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		5 / 12 THR C 790
SER C 562
LEU C 500
VAL C 499
PHE C 515
 None
 1.43A 3u9fH-5x6xC:
undetectable
3u9fI-5x6xC:
undetectable		 3u9fH-5x6xC:
undetectable
3u9fI-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		5 / 10 THR C 790
SER C 562
LEU C 500
VAL C 499
PHE C 515
 None
 1.43A 3u9fI-5x6xC:
undetectable		 3u9fI-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_L_CLML221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		5 / 12 THR C 790
SER C 562
LEU C 500
VAL C 499
PHE C 515
 None
 1.43A 3u9fJ-5x6xC:
undetectable
3u9fL-5x6xC:
undetectable		 3u9fJ-5x6xC:
undetectable
3u9fL-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFG_B_LEUB289_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		3 / 3 PHE C 600
SER C 490
SER C 486
 None
None
EDO  C 902 ( 4.2A)
 0.96A 3ufgB-5x6xC:
undetectable		 3ufgB-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 8 LEU C 779
HIS C 704
THR C 630
TRP C 722
 None
None
EDO  C 901 (-4.0A)
None
 1.20A 3wg7C-5x6xC:
undetectable
3wg7N-5x6xC:
undetectable
3wg7P-5x6xC:
undetectable		 3wg7C-5x6xC:
undetectable
3wg7N-5x6xC:
undetectable
3wg7P-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 6 PHE C 591
GLY C 149
PRO C 150
VAL C 588
 None
 1.02A 4dubA-5x6xC:
undetectable		 4dubA-5x6xC:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 5 ASP C 335
ASN C 344
ILE C 286
VAL C 330
 None
 1.20A 4hytA-5x6xC:
undetectable		 4hytA-5x6xC:
6.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_1
(MEMBRANE LIPOPROTEIN
TPN38(B))		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		5 / 12 SER C 115
ALA C 174
TYR C 178
ILE C 574
GLY C 114
 None
 1.31A 4iilA-5x6xC:
5.0		 4iilA-5x6xC:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T44A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 6 SER C  71
GLU C  67
VAL C  93
THR C  94
 None
 1.37A 4lnxA-5x6xC:
undetectable		 4lnxA-5x6xC:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA301_1
(CHITOSANASE)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		3 / 3 TYR C 585
GLY C 149
PRO C 150
 None
 0.56A 4qwpA-5x6xC:
undetectable		 4qwpA-5x6xC:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_X_BEZX801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 5 ILE C 245
GLY C 429
ILE C 433
LEU C 407
 None
 0.85A 5dzki-5x6xC:
undetectable
5dzkj-5x6xC:
undetectable
5dzkx-5x6xC:
undetectable		 5dzki-5x6xC:
undetectable
5dzkj-5x6xC:
undetectable
5dzkx-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Z_BEZZ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 4 ILE C 245
GLY C 429
ILE C 433
LEU C 407
 None
 0.78A 5dzkl-5x6xC:
undetectable
5dzkz-5x6xC:
undetectable		 5dzkl-5x6xC:
undetectable
5dzkz-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		5 / 12 ALA C 109
ILE C 208
TYR C 215
PHE C 181
MET C 577
 None
None
EDO  C 902 (-4.3A)
None
None
 1.32A 5jlcA-5x6xC:
undetectable		 5jlcA-5x6xC:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 6 VAL C 206
LEU C 277
SER C 278
ILE C 283
 None
 1.05A 5jw1A-5x6xC:
undetectable		 5jw1A-5x6xC:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_CE9A402_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		5 / 12 HIS C 704
LEU C 625
PHE C 629
THR C 630
LEU C 706
 None
None
None
EDO  C 901 (-4.0A)
None
 1.09A 5k9dA-5x6xC:
undetectable		 5k9dA-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKL_B_SAMB8009_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN,HISTONE H3.1
PEPTIDE,ZINC FINGER
DOMAIN-CONTAINING
PROTEIN)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		5 / 12 LEU C 503
GLY C 568
TYR C 565
PHE C 189
MET C 577
 None
 1.41A 5kklB-5x6xC:
undetectable		 5kklB-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8R_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		5 / 9 PHE C 242
GLY C 240
ALA C 408
LEU C 407
GLY C 429
 None
 1.37A 5l8rA-5x6xC:
undetectable		 5l8rA-5x6xC:
9.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_G_ACTG702_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		3 / 3 GLY C 672
THR C 675
ASN C 700
 None
 0.69A 5odiG-5x6xC:
undetectable		 5odiG-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_B_08JB602_1
(CYTOCHROME P450 3A4)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 8 ALA C 111
ILE C  79
ALA C  80
LEU C  83
 None
 0.66A 5te8B-5x6xC:
undetectable		 5te8B-5x6xC:
9.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 8 HIS C 704
THR C 630
TRP C 722
LEU C 779
 None
EDO  C 901 (-4.0A)
None
None
 1.20A 5wauA-5x6xC:
undetectable
5wauC-5x6xC:
undetectable
5wauc-5x6xC:
undetectable		 5wauA-5x6xC:
undetectable
5wauC-5x6xC:
undetectable
5wauc-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 7 LEU C 779
HIS C 704
THR C 630
TRP C 722
 None
None
EDO  C 901 (-4.0A)
None
 1.20A 5wauC-5x6xC:
undetectable
5waua-5x6xC:
undetectable
5wauc-5x6xC:
undetectable		 5wauC-5x6xC:
undetectable
5waua-5x6xC:
undetectable
5wauc-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA901_0
(MRNA CAPPING ENZYME
P5)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		5 / 11 SER C 232
ASP C 471
ALA C 472
SER C 488
ASN C 494
 None
 0.81A 5x6yA-5x6xC:
55.9		 5x6yA-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA901_0
(MRNA CAPPING ENZYME
P5)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		9 / 11 VAL C 209
GLY C 210
GLU C 230
ASP C 471
ALA C 472
SER C 488
LEU C 489
ASN C 491
ASN C 494
 None
 1.10A 5x6yA-5x6xC:
55.9		 5x6yA-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA901_0
(MRNA CAPPING ENZYME
P5)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		8 / 11 VAL C 209
GLY C 210
LYS C 231
ALA C 472
SER C 488
LEU C 489
ASN C 491
ASN C 494
 None
 1.15A 5x6yA-5x6xC:
55.9		 5x6yA-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_0
(MRNA CAPPING ENZYME
P5)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		11 / 12 LEU C 269
GLY C 287
PRO C 290
ALA C 291
HIS C 293
LYS C 310
GLU C 333
PHE C 334
THR C 360
VAL C 362
PHE C 369
 None
 0.64A 5x6yA-5x6xC:
55.9		 5x6yA-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_0
(MRNA CAPPING ENZYME
P5)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		11 / 12 LEU C 269
GLY C 287
PRO C 290
ALA C 291
HIS C 293
PRO C 309
LYS C 310
GLU C 333
PHE C 334
THR C 360
PHE C 369
 None
 0.60A 5x6yA-5x6xC:
55.9		 5x6yA-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_0
(MRNA CAPPING ENZYME
P5)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		8 / 12 LEU C 269
GLY C 287
PRO C 290
ALA C 291
HIS C 293
PRO C 309
LYS C 310
PHE C 336
 None
 1.33A 5x6yA-5x6xC:
55.9		 5x6yA-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_1
(MRNA CAPPING ENZYME
P5)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		3 / 3 TYR C 285
ASP C 308
ASP C 359
 None
 0.23A 5x6yA-5x6xC:
55.9		 5x6yA-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_B_SAMB901_0
(MRNA CAPPING ENZYME
P5)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		9 / 10 VAL C 209
GLY C 210
GLU C 230
LYS C 231
ASP C 471
ALA C 472
SER C 488
LEU C 489
ASN C 494
 None
 0.83A 5x6yB-5x6xC:
59.0		 5x6yB-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_B_SAMB901_0
(MRNA CAPPING ENZYME
P5)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		8 / 10 VAL C 209
GLY C 210
GLU C 230
LYS C 231
ASP C 471
LEU C 489
ASN C 491
ASN C 494
 None
 0.85A 5x6yB-5x6xC:
59.0		 5x6yB-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC901_0
(MRNA CAPPING ENZYME
P5)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		9 / 11 VAL C 209
GLY C 210
GLU C 230
LYS C 231
ASP C 471
ALA C 472
LEU C 489
ASN C 491
ASN C 494
 None
 1.04A 5x6yC-5x6xC:
53.1		 5x6yC-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC901_0
(MRNA CAPPING ENZYME
P5)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		9 / 11 VAL C 209
GLY C 210
LYS C 231
ASP C 471
ALA C 472
SER C 488
LEU C 489
ASN C 491
ASN C 494
 None
 1.23A 5x6yC-5x6xC:
53.1		 5x6yC-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC901_0
(MRNA CAPPING ENZYME
P5)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		8 / 11 VAL C 209
LYS C 231
SER C 232
ASP C 471
ALA C 472
SER C 488
LEU C 489
ASN C 494
 None
 1.00A 5x6yC-5x6xC:
53.1		 5x6yC-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		5 / 12 LEU C 269
TYR C 285
GLY C 287
GLU C 333
PHE C 307
 None
 1.35A 5x6yC-5x6xC:
53.1		 5x6yC-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		11 / 12 LEU C 269
TYR C 285
GLY C 287
PRO C 290
ALA C 291
HIS C 293
ASP C 308
PRO C 309
GLU C 333
PHE C 334
THR C 360
 None
 0.49A 5x6yC-5x6xC:
53.1		 5x6yC-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		11 / 12 LEU C 269
TYR C 285
GLY C 287
PRO C 290
ALA C 291
HIS C 293
ASP C 308
PRO C 309
LYS C 310
PHE C 334
THR C 360
 None
 0.42A 5x6yC-5x6xC:
53.1		 5x6yC-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_C_SALC201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 7 ARG C 648
VAL C 652
GLY C 670
TYR C 645
 None
None
None
EDO  C 901 (-4.8A)
 0.96A 5x80C-5x6xC:
undetectable
5x80D-5x6xC:
undetectable		 5x80C-5x6xC:
20.26
5x80D-5x6xC:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 8 HIS C 704
THR C 630
TRP C 722
LEU C 779
 None
EDO  C 901 (-4.0A)
None
None
 1.21A 5xdqA-5x6xC:
undetectable
5xdqC-5x6xC:
undetectable
5xdqP-5x6xC:
undetectable		 5xdqA-5x6xC:
undetectable
5xdqC-5x6xC:
undetectable
5xdqP-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 8 LEU C 779
HIS C 704
THR C 630
TRP C 722
 None
None
EDO  C 901 (-4.0A)
None
 1.20A 5xdqC-5x6xC:
undetectable
5xdqN-5x6xC:
undetectable
5xdqP-5x6xC:
undetectable		 5xdqC-5x6xC:
undetectable
5xdqN-5x6xC:
undetectable
5xdqP-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 8 HIS C 704
THR C 630
TRP C 722
LEU C 779
 None
EDO  C 901 (-4.0A)
None
None
 1.20A 5z84A-5x6xC:
undetectable
5z84C-5x6xC:
undetectable
5z84P-5x6xC:
undetectable		 5z84A-5x6xC:
undetectable
5z84C-5x6xC:
undetectable
5z84P-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		3 / 3 TYR C  73
ARG C  74
THR C  78
 None
 0.71A 5z84J-5x6xC:
undetectable		 5z84J-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 7 LEU C 779
HIS C 704
THR C 630
TRP C 722
 None
None
EDO  C 901 (-4.0A)
None
 1.22A 5z84C-5x6xC:
undetectable
5z84N-5x6xC:
undetectable
5z84P-5x6xC:
undetectable		 5z84C-5x6xC:
undetectable
5z84N-5x6xC:
undetectable
5z84P-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 8 LEU C 779
HIS C 704
THR C 630
TRP C 722
 None
None
EDO  C 901 (-4.0A)
None
 1.21A 5z86C-5x6xC:
undetectable
5z86N-5x6xC:
undetectable
5z86P-5x6xC:
undetectable		 5z86C-5x6xC:
undetectable
5z86N-5x6xC:
undetectable
5z86P-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 8 HIS C 704
THR C 630
TRP C 722
LEU C 779
 None
EDO  C 901 (-4.0A)
None
None
 1.21A 5zcoA-5x6xC:
undetectable
5zcoC-5x6xC:
undetectable
5zcoP-5x6xC:
undetectable		 5zcoA-5x6xC:
undetectable
5zcoC-5x6xC:
undetectable
5zcoP-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 8 LEU C 779
HIS C 704
THR C 630
TRP C 722
 None
None
EDO  C 901 (-4.0A)
None
 1.21A 5zcoC-5x6xC:
undetectable
5zcoN-5x6xC:
undetectable
5zcoP-5x6xC:
undetectable		 5zcoC-5x6xC:
undetectable
5zcoN-5x6xC:
undetectable
5zcoP-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 8 HIS C 704
THR C 630
TRP C 722
LEU C 779
 None
EDO  C 901 (-4.0A)
None
None
 1.20A 5zcpA-5x6xC:
undetectable
5zcpC-5x6xC:
undetectable
5zcpP-5x6xC:
undetectable		 5zcpA-5x6xC:
undetectable
5zcpC-5x6xC:
undetectable
5zcpP-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 8 LEU C 779
HIS C 704
THR C 630
TRP C 722
 None
None
EDO  C 901 (-4.0A)
None
 1.21A 5zcpC-5x6xC:
undetectable
5zcpN-5x6xC:
undetectable
5zcpP-5x6xC:
undetectable		 5zcpC-5x6xC:
undetectable
5zcpN-5x6xC:
undetectable
5zcpP-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5x6x MRNA CAPPING ENZYME
P5
(Rice
dwarf
virus) 		4 / 8 HIS C 704
THR C 630
TRP C 722
LEU C 779
 None
EDO  C 901 (-4.0A)
None
None
 1.21A 5zcqA-5x6xC:
undetectable
5zcqC-5x6xC:
undetectable
5zcqP-5x6xC:
undetectable		 5zcqA-5x6xC:
undetectable
5zcqC-5x6xC:
undetectable
5zcqP-5x6xC:
undetectable