SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5x7h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7W_A_MTXA301_1
(PTERIDINE REDUCTASE)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		5 / 12 SER A 140
ASP A 614
LEU A 612
TYR A 146
LEU A  86
 None
 1.29A 1e7wA-5x7hA:
undetectable		 1e7wA-5x7hA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7W_B_MTXB301_1
(PTERIDINE REDUCTASE)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		5 / 11 SER A 140
ASP A 614
LEU A 612
TYR A 146
LEU A  86
 None
 1.32A 1e7wB-5x7hA:
2.3		 1e7wB-5x7hA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		5 / 11 TYR A 354
ILE A 306
TYR A 294
HIS A 291
ILE A 290
 None
 1.37A 1fkfA-5x7hA:
undetectable		 1fkfA-5x7hA:
9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKJ_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		5 / 11 TYR A 354
ILE A 306
TYR A 294
HIS A 291
ILE A 290
 None
 1.38A 1fkjA-5x7hA:
undetectable		 1fkjA-5x7hA:
9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXF_A_MTXA1278_1
(PTERIDINE REDUCTASE
2)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		5 / 10 SER A 140
ASP A 614
LEU A 612
TYR A 146
THR A 708
 None
 1.39A 1mxfA-5x7hA:
3.4		 1mxfA-5x7hA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXF_B_MTXB2278_1
(PTERIDINE REDUCTASE
2)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		5 / 11 SER A 140
ASP A 614
LEU A 612
TYR A 146
THR A 708
 None
 1.39A 1mxfB-5x7hA:
3.6		 1mxfB-5x7hA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXF_C_MTXC3278_1
(PTERIDINE REDUCTASE
2)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		5 / 11 SER A 140
ASP A 614
LEU A 612
TYR A 146
THR A 708
 None
 1.42A 1mxfC-5x7hA:
3.5		 1mxfC-5x7hA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXF_D_MTXD4278_1
(PTERIDINE REDUCTASE
2)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		5 / 11 SER A 140
ASP A 614
LEU A 612
TYR A 146
THR A 708
 None
 1.45A 1mxfD-5x7hA:
1.7		 1mxfD-5x7hA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_C_MTXC353_1
(PTERIDINE REDUCTASE
1)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		5 / 12 SER A 140
ASP A 614
LEU A 612
TYR A 146
LEU A  86
 None
 1.29A 1p33C-5x7hA:
2.2		 1p33C-5x7hA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVT_A_PRLA311_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		4 / 8 GLU A 381
TYR A 413
ILE A 569
TYR A 149
 GLC  A 810 ( 2.4A)
None
None
None
 1.11A 1qvtA-5x7hA:
undetectable		 1qvtA-5x7hA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TCO_C_FK5C509_2
(FK506-BINDING
PROTEIN)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		5 / 11 TYR A 354
ILE A 306
TYR A 294
HIS A 291
ILE A 290
 None
 1.39A 1tcoC-5x7hA:
undetectable		 1tcoC-5x7hA:
9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		3 / 3 LYS A 648
ASP A 394
ASP A 362
 None
 1.00A 2br4A-5x7hA:
undetectable		 2br4A-5x7hA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_A_ADNA1301_1
(SUGAR KINASE MJ0406)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		5 / 12 GLY A 305
ALA A 230
PHE A 143
ASP A 142
ASP A 350
 None
 1.14A 2c49A-5x7hA:
undetectable		 2c49A-5x7hA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_B_T44B1395_1
(THYROXINE-BINDING
GLOBULIN)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		5 / 10 ALA A 366
LEU A 392
LEU A 410
SER A 370
LEU A 399
 None
 1.20A 2ceoB-5x7hA:
undetectable		 2ceoB-5x7hA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8L_A_SAMA400_0
(HYPOTHETICAL PROTEIN
LMO1582)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		5 / 12 ALA A 365
GLY A 363
VAL A 357
ASP A 358
PHE A 331
 None
None
GLC  A 810 ( 4.9A)
None
None
 0.94A 2f8lA-5x7hA:
undetectable		 2f8lA-5x7hA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FKE_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		5 / 11 TYR A 354
ILE A 306
TYR A 294
HIS A 291
ILE A 290
 None
 1.37A 2fkeA-5x7hA:
undetectable		 2fkeA-5x7hA:
9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1289_1
(FICOLIN-2)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		4 / 6 ASP A 376
ARG A 351
ASP A 304
ASP A 142
 None
 1.06A 2j2pE-5x7hA:
undetectable
2j2pF-5x7hA:
undetectable		 2j2pE-5x7hA:
15.35
2j2pF-5x7hA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		4 / 6 LEU A 529
ASN A 419
GLN A 504
ILE A 539
 None
 1.23A 2jn3A-5x7hA:
undetectable		 2jn3A-5x7hA:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VJ1_A_BEZA1303_0
(SARS CORONAVIRUS
MAIN PROTEINASE)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		3 / 3 HIS A 568
MET A 561
MET A 414
 None
 1.15A 2vj1A-5x7hA:
undetectable		 2vj1A-5x7hA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_A_FUAA2002_1
(SERUM ALBUMIN)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		4 / 9 ILE A 168
PHE A 182
VAL A 152
GLU A 154
 None
 0.77A 2vufA-5x7hA:
undetectable		 2vufA-5x7hA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		4 / 6 ALA A 597
LEU A 598
THR A 548
ASN A 415
 None
 0.90A 3b6hB-5x7hA:
undetectable		 3b6hB-5x7hA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		4 / 7 GLU A 170
TYR A 519
TYR A 470
TYR A 175
 None
GLC  A 818 ( 3.8A)
GLC  A 820 ( 4.7A)
None
 1.09A 3ku9B-5x7hA:
undetectable		 3ku9B-5x7hA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		4 / 6 TYR A 602
HIS A 568
THR A 567
VAL A 409
 None
 0.87A 3lb3A-5x7hA:
undetectable		 3lb3A-5x7hA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		4 / 6 TYR A 602
HIS A 568
THR A 567
VAL A 409
 None
 0.76A 3lb3B-5x7hA:
undetectable		 3lb3B-5x7hA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA207_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		4 / 7 GLU A  46
ASP A  44
ARG A  68
THR A  70
 None
 1.32A 3mbgA-5x7hA:
undetectable
3mbgB-5x7hA:
undetectable		 3mbgA-5x7hA:
12.57
3mbgB-5x7hA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		3 / 3 GLN A 310
PHE A 331
TYR A 238
 None
 0.95A 3ucjB-5x7hA:
undetectable		 3ucjB-5x7hA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_1
(CARBONIC ANHYDRASE)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		3 / 3 GLN A 310
PHE A 331
TYR A 238
 None
 0.95A 3ucjA-5x7hA:
undetectable		 3ucjA-5x7hA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UZZ_A_TESA501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		4 / 7 TYR A 413
HIS A 568
TYR A 379
TRP A 383
 None
 1.42A 3uzzA-5x7hA:
9.5		 3uzzA-5x7hA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UZZ_B_ASDB501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		4 / 8 TYR A 413
HIS A 568
TYR A 379
TRP A 383
 None
 1.43A 3uzzB-5x7hA:
9.3		 3uzzB-5x7hA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_1
(METHYLTRANSFERASE
MPPJ)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		3 / 3 ARG A 145
ASP A 376
ASP A 304
 None
 0.89A 4kicB-5x7hA:
undetectable		 4kicB-5x7hA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		5 / 12 ASP A  59
TYR A  55
SER A 113
THR A 135
ALA A 123
 None
 1.48A 4u14A-5x7hA:
undetectable		 4u14A-5x7hA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YO9_B_ACTB401_0
(3C-LIKE PROTEINASE)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		3 / 3 ARG A 210
ASP A 206
TYR A 183
 None
None
GLC  A 809 ( 4.4A)
 0.86A 4yo9B-5x7hA:
1.1		 4yo9B-5x7hA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNU_A_BEZA319_0
(SHKAI2IB)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		4 / 5 GLN A 310
HIS A 307
ILE A 237
TYR A 238
 None
 1.01A 5dnuA-5x7hA:
undetectable		 5dnuA-5x7hA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNV_A_BEZA304_0
(SHKAI2IB)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		4 / 5 GLN A 310
HIS A 307
ILE A 237
TYR A 238
 None
 1.02A 5dnvA-5x7hA:
undetectable		 5dnvA-5x7hA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		4 / 5 ALA A 235
PRO A 281
GLY A 322
LEU A 265
 None
 0.95A 5eslA-5x7hA:
undetectable		 5eslA-5x7hA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_1
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		5 / 12 GLY A 133
ILE A 125
PHE A 109
THR A  78
GLY A  77
 None
 0.85A 5koxA-5x7hA:
undetectable		 5koxA-5x7hA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_H_CVIH301_0
(REGULATORY PROTEIN
TETR)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		5 / 12 ALA A 430
SER A 428
GLU A 425
VAL A 449
TYR A 443
 None
None
CA  A 801 ( 3.1A)
None
None
 1.47A 5vlmH-5x7hA:
undetectable		 5vlmH-5x7hA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		5 / 7 ASN A 439
HIS A 440
ASP A 450
TRP A 507
ASN A 540
 GLC  A 811 ( 4.7A)
GLC  A 811 ( 3.7A)
None
GLC  A 811 ( 3.9A)
GLC  A 811 ( 2.8A)
 0.28A 5x7pA-5x7hA:
3.9		 5x7pA-5x7hA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA606_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		4 / 5 GLU A 593
ASP A 550
HIS A 552
THR A 548
 None
 1.02A 6b58A-5x7hA:
undetectable		 6b58A-5x7hA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		4 / 7 ASP A 174
GLN A 173
GLY A 133
VAL A  45
 None
 0.82A 6ekzA-5x7hA:
undetectable		 6ekzA-5x7hA:
7.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE
(Paenibacillus
sp.
598K) 		5 / 12 GLY A 572
GLN A 576
SER A 153
TYR A 582
ILE A 569
 None
GLC  A 820 ( 4.4A)
None
GLC  A 808 ( 4.2A)
None
 1.44A 6md4A-5x7hA:
undetectable		 6md4A-5x7hA:
8.76