SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5x7v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 5x7v NUCLEOSOME ASSEMBLY
PROTEIN
(Plasmodium
falciparum) 		5 / 8 THR A 137
GLY A 126
MET A 133
ILE A 124
VAL A 105
 None
 1.49A 1rxcE-5x7vA:
undetectable		 1rxcE-5x7vA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5x7v NUCLEOSOME ASSEMBLY
PROTEIN
(Plasmodium
falciparum) 		5 / 10 ILE A 166
PHE A 123
TRP A  80
ALA A  81
LEU A 101
 None
 1.23A 3lw5B-5x7vA:
undetectable		 3lw5B-5x7vA:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_0
(PUTATIVE REGULATORY
PROTEIN)		 5x7v NUCLEOSOME ASSEMBLY
PROTEIN
(Plasmodium
falciparum) 		5 / 12 LEU A  84
ILE A 121
ILE A  93
VAL A 151
PHE A 189
 None
 0.96A 3vw1D-5x7vA:
undetectable		 3vw1D-5x7vA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 5x7v NUCLEOSOME ASSEMBLY
PROTEIN
(Plasmodium
falciparum) 		5 / 8 THR A 137
GLY A 126
MET A 133
ILE A 124
VAL A 105
 None
 1.46A 4e1vG-5x7vA:
undetectable		 4e1vG-5x7vA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5x7v NUCLEOSOME ASSEMBLY
PROTEIN
(Plasmodium
falciparum) 		4 / 7 PHE A 123
TRP A  80
ALA A  81
LEU A 101
 None
 0.95A 4xk8A-5x7vA:
undetectable		 4xk8A-5x7vA:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA845_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5x7v NUCLEOSOME ASSEMBLY
PROTEIN
(Plasmodium
falciparum) 		4 / 8 PHE A 123
TRP A  80
ALA A  81
LEU A 101
 None
 0.94A 4xk8a-5x7vA:
undetectable		 4xk8a-5x7vA:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_2_PQN2843_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5x7v NUCLEOSOME ASSEMBLY
PROTEIN
(Plasmodium
falciparum) 		5 / 12 ILE A 166
PHE A 123
TRP A  80
ALA A  81
LEU A 101
 None
 1.23A 5oy02-5x7vA:
undetectable		 5oy02-5x7vA:
15.79