SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5x8h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CET_A_CLQA1001_0
(PROTEIN (L-LACTATE
DEHYDROGENASE))		 5x8h SHORT-CHAIN
DEHYDROGENASE
REDUCTASE
(Chryseobacterium
sp.
CA49) 		5 / 9 GLY A  13
ASP A  37
ILE A  38
ALA A  91
ILE A 114
 None
 0.87A 1cetA-5x8hA:
10.0		 1cetA-5x8hA:
26.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_1
(FTSJ)		 5x8h SHORT-CHAIN
DEHYDROGENASE
REDUCTASE
(Chryseobacterium
sp.
CA49) 		3 / 3 ASP A  37
ASP A  41
ASP A  63
 None
 0.68A 1eizA-5x8hA:
9.9		 1eizA-5x8hA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_1
(FTSJ)		 5x8h SHORT-CHAIN
DEHYDROGENASE
REDUCTASE
(Chryseobacterium
sp.
CA49) 		3 / 3 ASP A  37
ASP A  41
ASP A  63
 None
 0.72A 1ej0A-5x8hA:
9.9		 1ej0A-5x8hA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAO_A_SAMA245_0
(ERMC'
METHYLTRANSFERASE)		 5x8h SHORT-CHAIN
DEHYDROGENASE
REDUCTASE
(Chryseobacterium
sp.
CA49) 		5 / 12 GLY A  13
GLY A  15
ILE A  38
ASP A  63
ILE A 114
 None
 0.70A 1qaoA-5x8hA:
5.8		 1qaoA-5x8hA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 5x8h SHORT-CHAIN
DEHYDROGENASE
REDUCTASE
(Chryseobacterium
sp.
CA49) 		5 / 12 HIS A 145
ILE A 147
LEU A 241
VAL A 224
ILE A  18
 None
 1.23A 1zq9A-5x8hA:
6.4		 1zq9A-5x8hA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 5x8h SHORT-CHAIN
DEHYDROGENASE
REDUCTASE
(Chryseobacterium
sp.
CA49) 		4 / 6 THR A  12
ASP A  37
ASN A  39
ASP A  41
 None
 1.30A 2okcA-5x8hA:
5.6		 2okcA-5x8hA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_B_ADNB402_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 5x8h SHORT-CHAIN
DEHYDROGENASE
REDUCTASE
(Chryseobacterium
sp.
CA49) 		5 / 10 GLY A  15
ASP A  37
ILE A  38
ASN A  39
ASP A  63
 None
 0.51A 3ay0B-5x8hA:
6.9		 3ay0B-5x8hA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5x8h SHORT-CHAIN
DEHYDROGENASE
REDUCTASE
(Chryseobacterium
sp.
CA49) 		3 / 3 GLY A  15
ASP A  37
ASP A  63
 None
 0.43A 3ou7C-5x8hA:
5.3		 3ou7C-5x8hA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV8_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 5x8h SHORT-CHAIN
DEHYDROGENASE
REDUCTASE
(Chryseobacterium
sp.
CA49) 		5 / 12 GLY A  13
GLY A  15
ASP A  37
ILE A  38
ASP A  63
 None
 0.44A 4iv8A-5x8hA:
6.9		 4iv8A-5x8hA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV8_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 5x8h SHORT-CHAIN
DEHYDROGENASE
REDUCTASE
(Chryseobacterium
sp.
CA49) 		5 / 12 GLY A  13
GLY A  15
ASP A  37
ILE A  38
ASP A  63
 None
 0.44A 4iv8B-5x8hA:
7.1		 4iv8B-5x8hA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 5x8h SHORT-CHAIN
DEHYDROGENASE
REDUCTASE
(Chryseobacterium
sp.
CA49) 		5 / 12 THR A 167
TYR A 239
LEU A 241
LEU A 227
LEU A 223
 None
 1.17A 4qzuC-5x8hA:
undetectable		 4qzuC-5x8hA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5x8h SHORT-CHAIN
DEHYDROGENASE
REDUCTASE
(Chryseobacterium
sp.
CA49) 		5 / 12 GLU A  48
ASP A  49
GLU A  40
GLY A  15
GLU A 218
 None
 1.19A 4retC-5x8hA:
3.3		 4retC-5x8hA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 5x8h SHORT-CHAIN
DEHYDROGENASE
REDUCTASE
(Chryseobacterium
sp.
CA49) 		4 / 5 ILE A 189
PRO A 217
TYR A  26
VAL A  11
 None
 1.33A 4s0vA-5x8hA:
6.2		 4s0vA-5x8hA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUC_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 5x8h SHORT-CHAIN
DEHYDROGENASE
REDUCTASE
(Chryseobacterium
sp.
CA49) 		5 / 12 VAL A 224
GLY A 185
TYR A 240
ILE A 144
ILE A 147
 None
 1.03A 4xucA-5x8hA:
7.4		 4xucA-5x8hA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5x8h SHORT-CHAIN
DEHYDROGENASE
REDUCTASE
(Chryseobacterium
sp.
CA49) 		4 / 5 ALA A  14
PRO A 217
GLY A 212
LEU A 194
 None
 0.96A 5eslA-5x8hA:
undetectable		 5eslA-5x8hA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WY0_A_SAMA800_0
(SMALL RNA
2'-O-METHYLTRANSFERA
SE)		 5x8h SHORT-CHAIN
DEHYDROGENASE
REDUCTASE
(Chryseobacterium
sp.
CA49) 		6 / 12 GLY A  13
GLY A  15
ASP A  37
ILE A  38
ASN A  39
ILE A  18
 None
 0.62A 5wy0A-5x8hA:
5.7		 5wy0A-5x8hA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7F_A_SAMA301_0
(PUTATIVE
O-METHYLTRANSFERASE
RV1220C)		 5x8h SHORT-CHAIN
DEHYDROGENASE
REDUCTASE
(Chryseobacterium
sp.
CA49) 		5 / 12 GLY A  17
GLY A  13
GLY A  15
ILE A  38
ALA A  91
 None
 0.98A 5x7fA-5x8hA:
8.3		 5x7fA-5x8hA:
26.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5x8h SHORT-CHAIN
DEHYDROGENASE
REDUCTASE
(Chryseobacterium
sp.
CA49) 		4 / 5 TYR A 240
TYR A 239
GLY A 238
GLY A 237
 None
 1.11A 5x7pA-5x8hA:
undetectable		 5x7pA-5x8hA:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5x8h SHORT-CHAIN
DEHYDROGENASE
REDUCTASE
(Chryseobacterium
sp.
CA49) 		5 / 12 ALA A  23
GLY A  30
SER A  58
ASP A  37
ALA A  14
 None
 1.27A 5zvgA-5x8hA:
6.6		 5zvgA-5x8hA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5x8h SHORT-CHAIN
DEHYDROGENASE
REDUCTASE
(Chryseobacterium
sp.
CA49) 		5 / 12 ALA A  23
GLY A  30
SER A  58
ASP A  37
ALA A  14
 None
 1.27A 5zvgB-5x8hA:
7.0		 5zvgB-5x8hA:
23.35