SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5x8r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 5x8r 30S RIBOSOMAL
PROTEIN S5,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 8 THR e 282
VAL e 187
GLY e 188
VAL e 157
 None
 0.74A 2a1mB-5x8re:
undetectable		 2a1mB-5x8re:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5x8r 30S RIBOSOMAL
PROTEIN S5,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 8 THR e 282
VAL e 187
GLY e 188
VAL e 157
 None
 0.75A 2a1oA-5x8re:
undetectable		 2a1oA-5x8re:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAW_A_SUZA91_1
(SEGMENT POLARITY
PROTEIN DISHEVELLED
HOMOLOG DVL-1)		 5x8r PROTEIN CS22
(Spinacia
oleracea) 		5 / 11 GLY v 166
ILE v 126
ILE v 193
LEU v 188
VAL v 133
 None
 1.00A 2kawA-5x8rv:
undetectable		 2kawA-5x8rv:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 5x8r 30S RIBOSOMAL
PROTEIN S6 ALPHA,
CHLOROPLASTIC
(Spinacia
oleracea) 		3 / 3 GLU f 122
ASP f 117
TYR f 168
 None
 0.77A 2yvlB-5x8rf:
undetectable		 2yvlB-5x8rf:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 5x8r 30S RIBOSOMAL
PROTEIN S5,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 7 GLY e 244
GLY e 246
THR e 222
ALA e 242
 None
None
None
U  a   6 ( 3.2A)
 0.82A 3fpjB-5x8re:
undetectable		 3fpjB-5x8re:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW5_A_TOPA208_1
(DIHYDROFOLATE
REDUCTASE)		 5x8r PROTEIN CS22
(Spinacia
oleracea) 		5 / 11 ASN v  35
LEU v  38
LEU v  24
VAL v  95
THR v  86
 None
 1.33A 3jw5A-5x8rv:
undetectable		 3jw5A-5x8rv:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OF4_B_ACTB313_0
(NITROREDUCTASE)		 5x8r PROTEIN PLASTID PY
(Spinacia
oleracea) 		3 / 3 ALA y 103
VAL y 102
GLN y 165
 None
 0.73A 3of4B-5x8ry:
undetectable		 3of4B-5x8ry:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_B_FLPB701_1
(CYCLOOXYGENASE-2)		 5x8r 30S RIBOSOMAL
PROTEIN S5,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 11 VAL e 286
LEU e 238
VAL e 187
GLY e 185
ALA e 260
 None
 1.20A 3pghB-5x8re:
undetectable		 3pghB-5x8re:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5x8r 30S RIBOSOMAL
PROTEIN S6 ALPHA,
CHLOROPLASTIC
(Spinacia
oleracea) 		3 / 3 ARG f 123
GLU f 122
THR f 119
 None
 0.88A 3v4tA-5x8rf:
undetectable		 3v4tA-5x8rf:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5x8r PROTEIN PLASTID PY
(Spinacia
oleracea) 		3 / 3 THR y 135
VAL y 143
GLU y 111
 G  a 915 ( 4.7A)
None
C  a1178 ( 4.7A)
 0.66A 3v4tA-5x8ry:
undetectable
3v4tD-5x8ry:
undetectable		 3v4tA-5x8ry:
19.15
3v4tD-5x8ry:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG305_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5x8r PROTEIN PLASTID PY
(Spinacia
oleracea) 		3 / 3 ASP y 122
ARG y 130
LYS y 128
 None
 1.00A 3wipG-5x8ry:
undetectable		 3wipG-5x8ry:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5x8r PROTEIN PLASTID PY
(Spinacia
oleracea) 		5 / 12 PRO y  71
LEU y 136
ILE y 164
ALA y 103
SER y 101
 None
 1.16A 4a83A-5x8ry:
undetectable		 4a83A-5x8ry:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA301_0
(THAUMATIN-1)		 5x8r PROTEIN CS22
(Spinacia
oleracea) 		3 / 3 THR v 156
ASN v 163
SER v 162
 None
 0.75A 4tvtA-5x8rv:
undetectable		 4tvtA-5x8rv:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UY8_7_TRP71002_0
(TRYPTOPHANASE)		 5x8r PROTEIN CS22
(Spinacia
oleracea) 		4 / 4 ILE v  80
ASN v  84
ILE v  93
VAL v  26
 None
 0.93A 4uy87-5x8rv:
undetectable		 4uy87-5x8rv:
7.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_B_SALB801_1
(PROTEIN POLYBROMO-1)		 5x8r 30S RIBOSOMAL
PROTEIN S9,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 5 LEU i 139
TYR i 104
ALA i 134
ILE i 146
 C  a1197 ( 4.5A)
A  a1196 ( 4.7A)
None
None
 1.13A 4y03B-5x8ri:
undetectable		 4y03B-5x8ri:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A211_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 5x8r 30S RIBOSOMAL
PROTEIN S9,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 6 VAL i 132
LYS i 133
ALA i 134
GLN i 142
 None
None
None
C  a1197 ( 3.4A)
 0.94A 5i8fA-5x8ri:
undetectable		 5i8fA-5x8ri:
25.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 5x8r PROTEIN S10
(Spinacia
oleracea) 		3 / 3 LYS j 102
ASP j 190
ILE j  99
 U  a1075 ( 3.2A)
None
None
 0.91A 5kc4E-5x8rj:
undetectable		 5kc4E-5x8rj:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW5_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 5x8r 30S RIBOSOMAL
PROTEIN S9,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 8 GLY i  74
GLY i 149
LEU i 148
ALA i 145
 None
 0.76A 5vw5A-5x8ri:
undetectable		 5vw5A-5x8ri:
21.97