SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5x94'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V4T_H_ACTH504_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	5x94	TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11 (Homo sapiens)	3 / 3	LYS A 198 GLU A 195 TRP A 112	None	1.30A	3v4tH-5x94A: undetectable	3v4tH-5x94A: 24.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W9T_E_W9TE506_1 (HEMOLYTIC LECTIN CEL-III)	5x94	TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11 (Homo sapiens)	4 / 6	THR A 59 ASN A 58 GLY A 39 ASP A 40	None	1.07A	3w9tE-5x94A: undetectable	3w9tE-5x94A: 21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ACA_C_DXCC1478_0 (TRANSLATION ELONGATION FACTOR SELB)	5x94	TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11 (Homo sapiens)	4 / 7	GLY A 13 THR A 12 ILE A 11 THR A 22	None	0.83A	4acaC-5x94A: undetectable	4acaC-5x94A: 18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ODI_A_ACTA701_0 (HETERODISULFIDE REDUCTASE, SUBUNIT A)	5x94	TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11 (Homo sapiens)	3 / 3	LYS A 55 LYS A 35 SER A 36	None	1.33A	5odiA-5x94A: undetectable	5odiA-5x94A: 17.36

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3V4T_H_ACTH504_0","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","5x94","TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11","Homo sapiens",3,"LYS A 198;GLU A 195;TRP A 112","None","1.30A","3v4tH-5x94A:undetectable","3v4tH-5x94A:24.37"],["3W9T_E_W9TE506_1","HEMOLYTIC LECTIN CEL-III","5x94","TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11","Homo sapiens",4,"THR A  59;ASN A  58;GLY A  39;ASP A  40","None","1.07A","3w9tE-5x94A:undetectable","3w9tE-5x94A:21.88"],["4ACA_C_DXCC1478_0","TRANSLATION ELONGATION FACTOR SELB","5x94","TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11","Homo sapiens",4,"GLY A  13;THR A  12;ILE A  11;THR A  22","None","0.83A","4acaC-5x94A:undetectable","4acaC-5x94A:18.79"],["5ODI_A_ACTA701_0","HETERODISULFIDE REDUCTASE, SUBUNIT A","5x94","TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11","Homo sapiens",3,"LYS A  55;LYS A  35;SER A  36","None","1.33A","5odiA-5x94A:undetectable","5odiA-5x94A:17.36"]]