SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5x9a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_1
(CYTOCHROME P450 2C8)		 5x9a CALAXIN
(Ciona
intestinalis) 		5 / 12 SER A 188
VAL A  66
ALA A  69
THR A 104
VAL A  89
 None
 1.31A 2nniA-5x9aA:
undetectable		 2nniA-5x9aA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5x9a CALAXIN
(Ciona
intestinalis) 		4 / 7 LEU A 182
PHE A  90
ARG A  48
MET A  57
 None
 1.12A 2zxwN-5x9aA:
undetectable
2zxwW-5x9aA:
undetectable		 2zxwN-5x9aA:
undetectable
2zxwW-5x9aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 5x9a CALAXIN
(Ciona
intestinalis) 		4 / 7 GLU A  97
GLU A 100
TYR A 101
GLY A  86
 None
 0.71A 4fgzA-5x9aA:
undetectable		 4fgzA-5x9aA:
undetectable