SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5x9q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_1
(HMG-COA REDUCTASE)		 5x9q PUTATIVE
CYTIDYLYLTRANSFERASE
(Burkholderia
pseudomallei) 		4 / 7 ARG A 132
VAL A 131
SER A 128
ASP A 123
 None
 1.27A 1hwiC-5x9qA:
undetectable		 1hwiC-5x9qA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_2
(HMG-COA REDUCTASE)		 5x9q PUTATIVE
CYTIDYLYLTRANSFERASE
(Burkholderia
pseudomallei) 		4 / 7 ARG A 132
VAL A 131
SER A 128
ASP A 123
 None
 1.28A 1hwiD-5x9qA:
undetectable		 1hwiD-5x9qA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBC_A_BHAA396_0
(P-HYDROXYBENZOATE
HYDROXYLASE)		 5x9q PUTATIVE
CYTIDYLYLTRANSFERASE
(Burkholderia
pseudomallei) 		5 / 10 GLY A  31
VAL A  58
LEU A  85
LEU A  44
TYR A  43
 None
 1.04A 1pbcA-5x9qA:
undetectable		 1pbcA-5x9qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_A_PXLA1003_1
(PYRIDOXINE KINASE)		 5x9q PUTATIVE
CYTIDYLYLTRANSFERASE
(Burkholderia
pseudomallei) 		4 / 8 VAL A  91
VAL A  56
LEU A  88
HIS A  40
 None
 0.93A 2ddwA-5x9qA:
2.7		 2ddwA-5x9qA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_D_SAMD501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5x9q PUTATIVE
CYTIDYLYLTRANSFERASE
(Burkholderia
pseudomallei) 		5 / 10 HIS A  40
ILE A 141
GLY A 117
VAL A  56
ALA A  47
 None
 1.08A 5o96C-5x9qA:
2.7
5o96D-5x9qA:
2.9		 5o96C-5x9qA:
undetectable
5o96D-5x9qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_A_PQNA2001_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 5x9q PUTATIVE
CYTIDYLYLTRANSFERASE
(Burkholderia
pseudomallei) 		5 / 10 GLY A 135
ARG A 132
ALA A 138
LEU A 114
LEU A  36
 None
 1.42A 6hqbA-5x9qA:
undetectable
6hqbJ-5x9qA:
undetectable		 6hqbA-5x9qA:
20.43
6hqbJ-5x9qA:
26.09