SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5x9w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		4 / 5 THR A 648
THR A 276
HIS A 308
LEU A 625
 None
 1.35A 1d4fC-5x9wA:
undetectable		 1d4fC-5x9wA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_A_EAAA224_1
(GLUTATHIONE
TRANSFERASE)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		5 / 12 GLY A  66
LEU A  35
LEU A  24
VAL A  86
ALA A  72
 None
 0.99A 1gseA-5x9wA:
undetectable		 1gseA-5x9wA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_B_EAAB224_1
(GLUTATHIONE
TRANSFERASE)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		5 / 12 GLY A  66
LEU A  35
LEU A  24
VAL A  86
ALA A  72
 None
 1.04A 1gseB-5x9wA:
undetectable		 1gseB-5x9wA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H9Z_A_RWFA3001_1
(SERUM ALBUMIN)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		5 / 11 ALA A 532
LEU A 536
LEU A 529
LEU A 361
ALA A 398
 None
 1.13A 1h9zA-5x9wA:
undetectable		 1h9zA-5x9wA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		4 / 8 HIS A  20
LYS A  23
SER A  85
THR A 114
 None
 1.01A 1p7lC-5x9wA:
undetectable		 1p7lC-5x9wA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		4 / 8 HIS A  20
LYS A  23
SER A  85
THR A 114
 None
 1.01A 1p7lD-5x9wA:
undetectable		 1p7lD-5x9wA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		5 / 10 GLU A 257
LEU A 168
ARG A 167
ILE A 129
LEU A 251
 None
 1.47A 1qkuA-5x9wA:
undetectable		 1qkuA-5x9wA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		5 / 10 GLU A 257
LEU A 168
ARG A 167
ILE A 129
LEU A 251
 None
 1.46A 1qkuC-5x9wA:
undetectable		 1qkuC-5x9wA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		4 / 8 HIS A  20
LYS A  23
SER A  85
THR A 114
 None
 1.04A 1rg9A-5x9wA:
undetectable		 1rg9A-5x9wA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		4 / 8 HIS A  20
LYS A  23
SER A  85
THR A 114
 None
 1.03A 1rg9B-5x9wA:
undetectable		 1rg9B-5x9wA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		4 / 8 HIS A  20
LYS A  23
SER A  85
THR A 114
 None
 1.04A 1rg9C-5x9wA:
undetectable		 1rg9C-5x9wA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		4 / 8 HIS A  20
LYS A  23
SER A  85
THR A 114
 None
 1.04A 1rg9D-5x9wA:
undetectable		 1rg9D-5x9wA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		3 / 3 ALA A 171
VAL A 130
TRP A 143
 None
 0.85A 1tkqA-5x9wA:
undetectable		 1tkqA-5x9wA:
2.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XL6_B_SPMB3001_1
(INWARD RECTIFIER
POTASSIUM CHANNEL)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		4 / 5 ALA A 235
TYR A 239
ALA A 142
GLN A 244
 None
 1.15A 1xl6A-5x9wA:
undetectable
1xl6B-5x9wA:
undetectable		 1xl6A-5x9wA:
17.73
1xl6B-5x9wA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		5 / 12 LEU A 221
LEU A 256
GLY A 140
ALA A 232
ALA A 235
 None
 1.18A 2bm9C-5x9wA:
undetectable		 2bm9C-5x9wA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		5 / 12 LEU A 221
LEU A 256
GLY A 140
ALA A 232
ALA A 235
 None
 1.17A 2bm9D-5x9wA:
undetectable		 2bm9D-5x9wA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		3 / 3 SER A   7
GLU A  34
ASP A  31
 None
 0.65A 2zulA-5x9wA:
undetectable		 2zulA-5x9wA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		3 / 3 SER A   7
GLU A  34
ASP A  31
 None
 0.61A 3dmhA-5x9wA:
2.1		 3dmhA-5x9wA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_0
(PCZA361.24)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		5 / 12 ALA A 170
LEU A 168
SER A 145
GLY A 189
GLU A 172
 None
 0.96A 3g2oA-5x9wA:
undetectable		 3g2oA-5x9wA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		3 / 3 SER A 300
ASP A 547
ASP A 123
 None
 0.82A 3iv6C-5x9wA:
undetectable		 3iv6C-5x9wA:
16.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		3 / 3 ARG A 346
ASP A 360
ASP A 343
 None
 0.88A 3jayA-5x9wA:
undetectable		 3jayA-5x9wA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		3 / 3 ARG A 346
ASP A 360
ASP A 343
 None
 0.90A 3jb2A-5x9wA:
2.0		 3jb2A-5x9wA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		3 / 3 ARG A 346
ASP A 360
ASP A 343
 None
 0.89A 3jb3A-5x9wA:
undetectable		 3jb3A-5x9wA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		3 / 3 ASN A 420
ASN A 417
GLU A 518
 None
 0.93A 3kpdC-5x9wA:
undetectable		 3kpdC-5x9wA:
9.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		3 / 3 ASN A 420
ASN A 417
GLU A 518
 None
 0.87A 3kpdB-5x9wA:
undetectable		 3kpdB-5x9wA:
9.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_B_KKKB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		5 / 12 TYR A 210
PHE A 151
GLY A 231
ALA A 235
ILE A 240
 None
 1.41A 3ld6B-5x9wA:
undetectable		 3ld6B-5x9wA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_A_9PLA501_1
(CYTOCHROME P450 2E1)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		4 / 6 LEU A 334
ALA A 544
THR A 296
LEU A 371
 None
 0.83A 3t3zA-5x9wA:
undetectable		 3t3zA-5x9wA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_B_9PLB501_1
(CYTOCHROME P450 2E1)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		4 / 6 LEU A 334
ALA A 544
THR A 296
LEU A 371
 None
 0.85A 3t3zB-5x9wA:
undetectable		 3t3zB-5x9wA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_D_9PLD501_1
(CYTOCHROME P450 2E1)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		4 / 6 LEU A 334
ALA A 544
THR A 296
LEU A 371
 None
 0.83A 3t3zD-5x9wA:
undetectable		 3t3zD-5x9wA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I13_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		3 / 3 ASP A 644
ARG A 270
THR A 678
 None
 0.87A 4i13A-5x9wA:
undetectable		 4i13A-5x9wA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		4 / 4 ILE A 682
SER A 716
ASP A 644
ASP A 259
 None
 1.40A 4krhB-5x9wA:
3.1		 4krhB-5x9wA:
20.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		4 / 6 LEU A 155
GLU A 164
VAL A 130
ALA A 131
 None
 0.89A 4nkvC-5x9wA:
undetectable		 4nkvC-5x9wA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX6_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		5 / 12 LEU A 193
THR A 114
ILE A 129
LEU A 236
ILE A 240
 None
 1.08A 4nx6A-5x9wA:
undetectable		 4nx6A-5x9wA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX7_A_FOLA202_0
(DIHYDROFOLATE
REDUCTASE)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		5 / 12 LEU A 193
THR A 114
ILE A 129
LEU A 236
ILE A 240
 None
 1.06A 4nx7A-5x9wA:
undetectable		 4nx7A-5x9wA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		5 / 12 LEU A 193
THR A 114
ILE A 129
LEU A 236
ILE A 240
 None
 1.05A 4pstA-5x9wA:
undetectable		 4pstA-5x9wA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1F_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		5 / 12 ASP A 360
LEU A 361
SER A 363
LEU A 529
ILE A 351
 None
 1.14A 4x1fA-5x9wA:
undetectable		 4x1fA-5x9wA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDP_H_EVPH2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		4 / 6 SER A 145
GLU A 150
GLY A  83
GLY A 189
 None
 0.85A 5cdpA-5x9wA:
undetectable
5cdpB-5x9wA:
undetectable		 5cdpA-5x9wA:
21.33
5cdpB-5x9wA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		3 / 3 LYS A 414
ASP A 415
ARG A 357
 None
 0.67A 5jwaA-5x9wA:
undetectable
5jwaH-5x9wA:
undetectable		 5jwaA-5x9wA:
19.40
5jwaH-5x9wA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		4 / 7 LEU A 279
ILE A 646
THR A 648
MET A 265
 None
 0.85A 5ljcA-5x9wA:
undetectable		 5ljcA-5x9wA:
9.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		5 / 12 VAL A 688
ASP A 686
LEU A 698
ALA A 701
LEU A 604
 None
ANP  A 901 (-2.7A)
None
None
None
 1.08A 5nd7B-5x9wA:
undetectable		 5nd7B-5x9wA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_1
(SCRFP-TAG,GP41)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		5 / 12 LEU A 521
GLY A 524
LYS A 527
LEU A 401
LEU A 361
 None
 1.24A 5nwvA-5x9wA:
undetectable		 5nwvA-5x9wA:
3.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		5 / 12 LEU A 168
ILE A 139
LEU A 165
ALA A 232
LEU A 175
 None
 1.10A 5og9B-5x9wA:
undetectable		 5og9B-5x9wA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		4 / 7 VAL A 106
ILE A 109
VAL A  25
ALA A  87
 None
 0.59A 5osrA-5x9wA:
undetectable		 5osrA-5x9wA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		4 / 8 HIS A  20
LYS A  23
SER A  85
THR A 114
 None
 1.03A 5t8sB-5x9wA:
undetectable		 5t8sB-5x9wA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		5 / 12 LEU A 383
GLY A 630
ALA A 323
PRO A 564
THR A 629
 None
 1.34A 5x6yC-5x9wA:
2.2		 5x6yC-5x9wA:
22.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6L_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		5 / 9 ILE A 341
ALA A 295
ASP A 547
LEU A 546
PRO A 392
 None
 1.08A 5z6lA-5x9wA:
undetectable		 5z6lA-5x9wA:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_A_TRPA403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		4 / 8 ARG A 346
THR A 114
ILE A 240
PRO A 248
 None
 1.09A 6a4iA-5x9wA:
0.8		 6a4iA-5x9wA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPL_B_PA1B605_1
(LIPID A EXPORT
ATP-BINDING/PERMEASE
PROTEIN MSBA)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		3 / 3 ARG A 690
ARG A 618
ARG A 649
 ANP  A 901 ( 4.6A)
None
None
 1.06A 6bplA-5x9wA:
4.0
6bplB-5x9wA:
9.9		 6bplA-5x9wA:
7.69
6bplB-5x9wA:
7.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
RNA POLYMERASE SIGMA
FACTOR SIGA)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		4 / 4 LEU A 251
ASP A 252
GLN A 537
VAL A 107
 None
 1.39A 6bzoF-5x9wA:
1.9		 6bzoF-5x9wA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		4 / 8 ILE A 317
GLN A 321
THR A 325
SER A 382
 None
 0.97A 6c06C-5x9wA:
undetectable		 6c06C-5x9wA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA821_0
(GEPHYRIN)		 5x9w DNA MISMATCH REPAIR
PROTEIN MUTS
(Neisseria
gonorrhoeae) 		3 / 3 ARG A  28
PHE A  32
GLY A  30
 None
 0.67A 6fgdA-5x9wA:
undetectable		 6fgdA-5x9wA:
20.18