SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xao'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		4 / 4 VAL A 236
ALA A 234
LEU A 422
PHE A 282
 None
 1.10A 1q97B-5xaoA:
undetectable		 1q97B-5xaoA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_A_RBFA300_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		5 / 11 GLY A  20
SER A  21
HIS A  26
HIS A 384
ALA A 367
 None
 1.38A 2a58A-5xaoA:
4.8
2a58E-5xaoA:
4.0		 2a58A-5xaoA:
16.55
2a58E-5xaoA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_D_RBFD303_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		5 / 11 HIS A 384
ALA A 367
GLY A  20
SER A  21
HIS A  26
 None
 1.38A 2a58C-5xaoA:
3.9
2a58D-5xaoA:
4.8		 2a58C-5xaoA:
16.55
2a58D-5xaoA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_B_STRB302_1
(MINERALOCORTICOID
RECEPTOR)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		5 / 12 LEU A  63
LEU A 114
ALA A 113
SER A 109
LEU A 107
 None
 1.25A 2aa5B-5xaoA:
undetectable		 2aa5B-5xaoA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_B_RBFB202_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		5 / 11 GLY A 382
TYR A  32
ARG A   5
GLU A 390
VAL A  37
 None
 1.30A 2fl5A-5xaoA:
undetectable
2fl5B-5xaoA:
undetectable
2fl5F-5xaoA:
undetectable		 2fl5A-5xaoA:
20.19
2fl5B-5xaoA:
18.89
2fl5F-5xaoA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		4 / 5 ASP A 130
LEU A 133
LYS A 134
ARG A 141
 None
 1.30A 2gj5A-5xaoA:
undetectable		 2gj5A-5xaoA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_A_SAMA301_0
(YCGJ)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		5 / 12 GLY A  14
GLY A  16
THR A  23
ASP A  41
ALA A  42
 FAD  A 501 (-3.4A)
FAD  A 501 (-4.2A)
None
FAD  A 501 (-2.9A)
FAD  A 501 (-4.3A)
 0.77A 2gluA-5xaoA:
2.9		 2gluA-5xaoA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_A_SAMA301_0
(YCGJ)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		5 / 12 GLY A  14
GLY A  17
THR A  23
ASP A  41
ALA A  42
 FAD  A 501 (-3.4A)
FAD  A 501 (-3.3A)
None
FAD  A 501 (-2.9A)
FAD  A 501 (-4.3A)
 0.87A 2gluA-5xaoA:
2.9		 2gluA-5xaoA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		4 / 4 SER A  50
GLY A  17
HIS A 373
ASP A 350
 FAD  A 501 (-2.8A)
FAD  A 501 (-3.3A)
None
None
 1.28A 2oxtC-5xaoA:
2.1		 2oxtC-5xaoA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_H_CSCH1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		5 / 12 LEU A 378
THR A  18
PHE A  85
HIS A  26
VAL A 385
 None
FAD  A 501 (-3.3A)
None
None
None
 1.39A 2vavH-5xaoA:
undetectable		 2vavH-5xaoA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		5 / 12 SER A  50
GLY A  52
GLY A  20
THR A  23
ILE A 381
 FAD  A 501 (-2.8A)
FAD  A 501 (-3.7A)
None
None
None
 0.98A 2wa2B-5xaoA:
2.3		 2wa2B-5xaoA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_B_QPSB1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		5 / 12 GLN A 229
ASP A  68
VAL A  67
ASN A  65
HIS A 373
 None
 1.10A 2x2iB-5xaoA:
undetectable		 2x2iB-5xaoA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		5 / 12 GLN A 229
ASP A  68
VAL A  67
ASN A  65
HIS A 373
 None
 1.23A 2x2iC-5xaoA:
undetectable		 2x2iC-5xaoA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_D_QPSD1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		5 / 12 GLN A 229
ASP A  68
VAL A  67
ASN A  65
HIS A 373
 None
 1.15A 2x2iD-5xaoA:
undetectable		 2x2iD-5xaoA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_B_SAMB402_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		5 / 12 PHE A 151
PHE A 263
PRO A 254
ASN A 258
ASP A 277
 None
 1.16A 2zznB-5xaoA:
undetectable		 2zznB-5xaoA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_A_SAMA300_0
(PUTATIVE
METHYLTRANSFERASE)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		5 / 12 GLY A  14
GLY A  16
ASP A  41
SER A 185
ALA A 216
 FAD  A 501 (-3.4A)
FAD  A 501 (-4.2A)
FAD  A 501 (-2.9A)
FAD  A 501 (-4.7A)
FAD  A 501 (-4.0A)
 1.20A 3t7sA-5xaoA:
2.6		 3t7sA-5xaoA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		5 / 11 LEU A 378
ILE A  45
VAL A 167
LEU A 171
VAL A  28
 None
 1.11A 3w67A-5xaoA:
undetectable		 3w67A-5xaoA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		5 / 12 LEU A 378
ILE A  45
VAL A 167
LEU A 171
VAL A  28
 None
 1.08A 3w68A-5xaoA:
undetectable		 3w68A-5xaoA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_A_LURA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		5 / 12 TYR A 170
VAL A 167
LEU A 171
GLY A 382
LEU A 378
 None
 1.11A 4rrxA-5xaoA:
undetectable		 4rrxA-5xaoA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_B_LURB706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		5 / 12 TYR A 170
VAL A 167
LEU A 171
GLY A 382
LEU A 378
 None
 1.10A 4rrxB-5xaoA:
undetectable		 4rrxB-5xaoA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		5 / 11 ASP A 260
ALA A 324
HIS A  99
ASP A  96
ASP A 103
 None
 1.23A 4uuuA-5xaoA:
undetectable
4uuuB-5xaoA:
undetectable		 4uuuA-5xaoA:
14.83
4uuuB-5xaoA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_D_QDND602_1
(CYTOCHROME P450 2D6)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		5 / 10 LEU A  63
ALA A 351
ASP A 347
SER A 413
ALA A 410
 None
 1.35A 4wnuD-5xaoA:
undetectable		 4wnuD-5xaoA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		3 / 3 VAL A  37
VAL A 176
GLN A 174
 None
 0.64A 5qgnA-5xaoA:
undetectable		 5qgnA-5xaoA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		3 / 3 VAL A  37
VAL A 176
GLN A 174
 None
 0.62A 5qgyA-5xaoA:
undetectable		 5qgyA-5xaoA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		3 / 3 VAL A  37
VAL A 176
GLN A 174
 None
 0.63A 5qgzA-5xaoA:
undetectable		 5qgzA-5xaoA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		3 / 3 VAL A  37
VAL A 176
GLN A 174
 None
 0.64A 5qh0A-5xaoA:
undetectable		 5qh0A-5xaoA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		3 / 3 VAL A  37
VAL A 176
GLN A 174
 None
 0.63A 5qh2A-5xaoA:
undetectable		 5qh2A-5xaoA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		3 / 3 VAL A  37
VAL A 176
GLN A 174
 None
 0.63A 5qh3A-5xaoA:
undetectable		 5qh3A-5xaoA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		3 / 3 VAL A  37
VAL A 176
GLN A 174
 None
 0.62A 5qh5A-5xaoA:
undetectable		 5qh5A-5xaoA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		3 / 3 VAL A  37
VAL A 176
GLN A 174
 None
 0.65A 5qh6A-5xaoA:
undetectable		 5qh6A-5xaoA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		3 / 3 VAL A  37
VAL A 176
GLN A 174
 None
 0.64A 5qh7A-5xaoA:
undetectable		 5qh7A-5xaoA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		3 / 3 VAL A  37
VAL A 176
GLN A 174
 None
 0.67A 5qhaA-5xaoA:
undetectable		 5qhaA-5xaoA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		3 / 3 VAL A  37
VAL A 176
GLN A 174
 None
 0.64A 5qhhA-5xaoA:
undetectable		 5qhhA-5xaoA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VM8_B_SAMB301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		5 / 10 GLY A 184
GLY A 179
LEU A 214
ILE A  11
THR A 201
 None
 0.99A 5vm8B-5xaoA:
undetectable		 5vm8B-5xaoA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRZ_A_H8JA1206_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 5xao UNCHARACTERIZED
PROTEIN
(Parastagonospora
nodorum) 		5 / 12 VAL A 199
THR A 201
VAL A 365
GLY A 184
VAL A 224
 None
 0.93A 6drzA-5xaoA:
undetectable		 6drzA-5xaoA:
20.26