SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xaq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VCT_D_ASDD1223_1 (GLUTATHIONE S-TRANSFERASE A2)	5xaq	PROBABLE D-TYROSYL-TRNA(TYR) DEACYLASE 2 (Mus musculus)	4 / 7	ILE A 44 LEU A 125 PHE A 122 PHE A 48	None	1.03A	2vctD-5xaqA: undetectable	2vctD-5xaqA: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UXQ_A_0LIA1752_2 (FIBROBLAST GROWTH FACTOR RECEPTOR 4)	5xaq	PROBABLE D-TYROSYL-TRNA(TYR) DEACYLASE 2 (Mus musculus)	4 / 7	VAL A 130 ILE A 89 ARG A 21 ILE A 90	None	0.85A	4uxqA-5xaqA: undetectable	4uxqA-5xaqA: 11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Y0P_A_TE4A201_1 (BETA-LACTOGLOBULIN)	5xaq	PROBABLE D-TYROSYL-TRNA(TYR) DEACYLASE 2 (Mus musculus)	5 / 12	LEU A 57 LEU A 42 ILE A 44 ILE A 89 VAL A 67	None	1.28A	4y0pA-5xaqA: undetectable	4y0pA-5xaqA: 20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EMU_B_SAMB301_0 (TRNA (GUANINE(9)-/ADENINE (9)-N1)-METHYLTRANSF ERASE)	5xaq	PROBABLE D-TYROSYL-TRNA(TYR) DEACYLASE 2 (Mus musculus)	5 / 12	LEU A 88 GLY A 41 ILE A 80 ILE A 90 VAL A 46	None	1.06A	6emuB-5xaqA: undetectable	6emuB-5xaqA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EMU_C_SAMC301_0 (TRNA (GUANINE(9)-/ADENINE (9)-N1)-METHYLTRANSF ERASE)	5xaq	PROBABLE D-TYROSYL-TRNA(TYR) DEACYLASE 2 (Mus musculus)	5 / 12	LEU A 88 GLY A 41 ILE A 80 ILE A 90 VAL A 46	None	1.02A	6emuC-5xaqA: undetectable	6emuC-5xaqA: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2VCT_D_ASDD1223_1","GLUTATHIONE S-TRANSFERASE A2","5xaq","PROBABLE D-TYROSYL-TRNA(TYR) DEACYLASE 2","Mus musculus",4,"ILE A  44;LEU A 125;PHE A 122;PHE A  48","None","1.03A","2vctD-5xaqA:undetectable","2vctD-5xaqA:16.67"],["4UXQ_A_0LIA1752_2","FIBROBLAST GROWTH FACTOR RECEPTOR 4","5xaq","PROBABLE D-TYROSYL-TRNA(TYR) DEACYLASE 2","Mus musculus",4,"VAL A 130;ILE A  89;ARG A  21;ILE A  90","None","0.85A","4uxqA-5xaqA:undetectable","4uxqA-5xaqA:11.82"],["4Y0P_A_TE4A201_1","BETA-LACTOGLOBULIN","5xaq","PROBABLE D-TYROSYL-TRNA(TYR) DEACYLASE 2","Mus musculus",5,"LEU A  57;LEU A  42;ILE A  44;ILE A  89;VAL A  67","None","1.28A","4y0pA-5xaqA:undetectable","4y0pA-5xaqA:20.89"],["6EMU_B_SAMB301_0","TRNA (GUANINE(9)-\/ADENINE(9)-N1)-METHYLTRANSFERASE","5xaq","PROBABLE D-TYROSYL-TRNA(TYR) DEACYLASE 2","Mus musculus",5,"LEU A  88;GLY A  41;ILE A  80;ILE A  90;VAL A  46","None","1.06A","6emuB-5xaqA:undetectable","6emuB-5xaqA:undetectable"],["6EMU_C_SAMC301_0","TRNA (GUANINE(9)-\/ADENINE(9)-N1)-METHYLTRANSFERASE","5xaq","PROBABLE D-TYROSYL-TRNA(TYR) DEACYLASE 2","Mus musculus",5,"LEU A  88;GLY A  41;ILE A  80;ILE A  90;VAL A  46","None","1.02A","6emuC-5xaqA:undetectable","6emuC-5xaqA:undetectable"]]