SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xaw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EII_A_RTLA135_0 (CELLULAR RETINOL-BINDING PROTEIN II)	5xaw	SODIUM CHANNEL SUBUNIT BETA-4 (Homo sapiens)	5 / 12	ALA A 75 PHE A 76 LEU A 121 LEU A 79 ARG A 100	PG4 A 202 ( 4.5A) P33 A 201 ( 4.9A) None None PG4 A 202 (-4.0A)	1.38A	1eiiA-5xawA: undetectable	1eiiA-5xawA: 26.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EM2_A_SALA501_1 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR SAR2349)	5xaw	SODIUM CHANNEL SUBUNIT BETA-4 (Homo sapiens)	4 / 5	TYR A 129 LEU A 51 LEU A 121 ARG A 100	None None None PG4 A 202 (-4.0A)	1.36A	4em2A-5xawA: undetectable	4em2A-5xawA: 21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECM_A_LEUA602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	5xaw	SODIUM CHANNEL SUBUNIT BETA-4 (Homo sapiens)	4 / 5	THR A 146 ALA A 145 THR A 130 HIS A 144	None	1.26A	5ecmA-5xawA: undetectable	5ecmA-5xawA: 12.87