SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xb0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		7 / 9 TYR A 147
ASP A 158
PHE A 166
ILE A 172
TRP A 175
TYR A 198
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
 1.10A 1bkfA-5xb0A:
15.4		 1bkfA-5xb0A:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		7 / 9 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
 0.66A 1bkfA-5xb0A:
15.4		 1bkfA-5xb0A:
32.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9H_A_RAPA108_1
(FKBP12.6)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		7 / 12 TYR A 147
ASP A 158
PHE A 166
ILE A 172
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
None
None
None
 1.10A 1c9hA-5xb0A:
14.8		 1c9hA-5xb0A:
29.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9H_A_RAPA108_1
(FKBP12.6)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		7 / 12 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.68A 1c9hA-5xb0A:
14.8		 1c9hA-5xb0A:
29.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 THR A 133
PRO A 135
THR A 184
 None
 0.95A 1dscC-5xb0A:
undetectable		 1dscC-5xb0A:
15.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FAP_A_RAPA108_1
(FK506-BINDING
PROTEIN)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 12 TYR A 147
ASP A 158
PHE A 166
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.04A 1fapA-5xb0A:
15.6		 1fapA-5xb0A:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FAP_A_RAPA108_1
(FK506-BINDING
PROTEIN)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 12 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.66A 1fapA-5xb0A:
15.6		 1fapA-5xb0A:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FAP_A_RAPA108_1
(FK506-BINDING
PROTEIN)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 TYR A 147
VAL A 171
TRP A 175
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
 0.95A 1fapA-5xb0A:
15.6		 1fapA-5xb0A:
32.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 THR A 184
THR A 133
PRO A 135
 None
 0.89A 1fjaD-5xb0A:
undetectable		 1fjaD-5xb0A:
15.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKB_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		7 / 12 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
 0.66A 1fkbA-5xb0A:
15.4		 1fkbA-5xb0A:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKB_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		6 / 12 TYR A 147
PHE A 166
ILE A 172
TRP A 175
TYR A 198
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
 1.03A 1fkbA-5xb0A:
15.4		 1fkbA-5xb0A:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKB_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 TYR A 147
VAL A 171
TRP A 175
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
 1.04A 1fkbA-5xb0A:
15.4		 1fkbA-5xb0A:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		6 / 11 PHE A 166
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.09A 1fkfA-5xb0A:
15.3		 1fkfA-5xb0A:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 11 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.63A 1fkfA-5xb0A:
15.3		 1fkfA-5xb0A:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKJ_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		6 / 11 PHE A 166
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.09A 1fkjA-5xb0A:
15.3		 1fkjA-5xb0A:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKJ_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 11 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.63A 1fkjA-5xb0A:
15.3		 1fkjA-5xb0A:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKL_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 12 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.70A 1fklA-5xb0A:
15.5		 1fklA-5xb0A:
31.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKL_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		7 / 12 TYR A 147
PHE A 166
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.01A 1fklA-5xb0A:
15.5		 1fklA-5xb0A:
31.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKL_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 TYR A 147
VAL A 171
TRP A 175
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
 1.06A 1fklA-5xb0A:
15.5		 1fklA-5xb0A:
31.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PBK_A_RAPA225_1
(FKBP25)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 12 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.70A 1pbkA-5xb0A:
15.2		 1pbkA-5xb0A:
31.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PBK_A_RAPA225_1
(FKBP25)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		6 / 12 VAL A 171
ILE A 172
TRP A 175
ALA A 203
ILE A 207
PHE A 215
 TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.23A 1pbkA-5xb0A:
15.2		 1pbkA-5xb0A:
31.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_A_FK5A301_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 9 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.67A 1q6iA-5xb0A:
20.7		 1q6iA-5xb0A:
28.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_B_FK5B401_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 10 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.58A 1q6iB-5xb0A:
20.5		 1q6iB-5xb0A:
28.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TCO_C_FK5C509_2
(FK506-BINDING
PROTEIN)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		7 / 11 PHE A 166
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.07A 1tcoC-5xb0A:
15.0		 1tcoC-5xb0A:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TCO_C_FK5C509_2
(FK506-BINDING
PROTEIN)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 11 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.77A 1tcoC-5xb0A:
15.0		 1tcoC-5xb0A:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAT_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		7 / 11 PHE A 166
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.01A 1yatA-5xb0A:
17.5		 1yatA-5xb0A:
32.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAT_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 11 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.65A 1yatA-5xb0A:
17.5		 1yatA-5xb0A:
32.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG3_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		7 / 11 TYR A 147
ASP A 158
PHE A 166
ILE A 172
TRP A 175
TYR A 198
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
 1.11A 2dg3A-5xb0A:
15.2		 2dg3A-5xb0A:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG3_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		7 / 11 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
 0.67A 2dg3A-5xb0A:
15.2		 2dg3A-5xb0A:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG3_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 11 TYR A 147
ASP A 158
VAL A 171
TRP A 175
ILE A 207
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
 1.34A 2dg3A-5xb0A:
15.2		 2dg3A-5xb0A:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG4_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		6 / 11 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TYR A 198
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
 0.70A 2dg4A-5xb0A:
14.9		 2dg4A-5xb0A:
31.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG9_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		6 / 11 TYR A 147
ASP A 158
PHE A 166
ILE A 172
TYR A 198
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
None
None
 1.18A 2dg9A-5xb0A:
15.0		 2dg9A-5xb0A:
31.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG9_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		6 / 11 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TYR A 198
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
 0.72A 2dg9A-5xb0A:
15.0		 2dg9A-5xb0A:
31.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FKE_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		6 / 11 PHE A 166
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.09A 2fkeA-5xb0A:
15.4		 2fkeA-5xb0A:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FKE_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 11 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.62A 2fkeA-5xb0A:
15.4		 2fkeA-5xb0A:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VCD_A_RAPA138_1
(OUTER MEMBRANE
PROTEIN MIP)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 11 TYR A 147
PHE A 157
ASP A 158
PHE A 166
VAL A 171
ILE A 172
TRP A 175
TYR A 198
 TLA  A 301 ( 4.4A)
None
TLA  A 301 (-3.7A)
TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
 1.01A 2vcdA-5xb0A:
19.0		 2vcdA-5xb0A:
40.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VN1_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		6 / 11 PHE A 157
PHE A 166
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 None
TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
None
None
None
 1.23A 2vn1A-5xb0A:
16.2		 2vn1A-5xb0A:
35.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VN1_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 11 TYR A 147
PHE A 157
ASP A 158
VAL A 171
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
None
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.87A 2vn1A-5xb0A:
16.2		 2vn1A-5xb0A:
35.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VN1_B_FK5B501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 10 PHE A 166
ILE A 172
TRP A 175
TYR A 198
PHE A 215
 TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
 1.13A 2vn1B-5xb0A:
16.2		 2vn1B-5xb0A:
35.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VN1_B_FK5B501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		7 / 10 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
 0.76A 2vn1B-5xb0A:
16.2		 2vn1B-5xb0A:
35.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_2
(HIV-1 PROTEASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 ARG A 146
VAL A 222
THR A 184
 None
 0.70A 3cyxA-5xb0A:
undetectable		 3cyxA-5xb0A:
20.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IHZ_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		7 / 10 PHE A 166
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.03A 3ihzA-5xb0A:
16.0		 3ihzA-5xb0A:
31.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IHZ_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 10 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.67A 3ihzA-5xb0A:
16.0		 3ihzA-5xb0A:
31.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IHZ_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 8 ASP A 158
PHE A 166
TRP A 175
TYR A 198
ILE A 207
 TLA  A 301 (-3.7A)
TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
None
None
 1.23A 3ihzB-5xb0A:
16.4		 3ihzB-5xb0A:
31.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IHZ_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 8 TYR A 147
ASP A 158
TRP A 175
TYR A 198
ILE A 207
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
None
None
 0.64A 3ihzB-5xb0A:
16.4		 3ihzB-5xb0A:
31.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KZ7_A_RAPA225_1
(FK506-BINDING
PROTEIN 3)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 10 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.69A 3kz7A-5xb0A:
14.8		 3kz7A-5xb0A:
33.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O5R_A_FK5A1001_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		7 / 11 PHE A 166
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.05A 3o5rA-5xb0A:
16.3		 3o5rA-5xb0A:
31.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O5R_A_FK5A1001_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 11 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.69A 3o5rA-5xb0A:
16.3		 3o5rA-5xb0A:
31.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UF8_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		6 / 10 PHE A 166
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.13A 3uf8A-5xb0A:
16.8		 3uf8A-5xb0A:
31.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UF8_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 10 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.71A 3uf8A-5xb0A:
16.8		 3uf8A-5xb0A:
31.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQA_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		6 / 10 PHE A 166
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.14A 3uqaA-5xb0A:
16.7		 3uqaA-5xb0A:
32.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQA_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 10 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.73A 3uqaA-5xb0A:
16.7		 3uqaA-5xb0A:
32.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQB_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		6 / 8 TYR A 147
VAL A 171
ILE A 172
TRP A 175
TYR A 198
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
 0.40A 3uqbA-5xb0A:
16.8		 3uqbA-5xb0A:
31.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQB_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		6 / 8 TYR A 147
VAL A 171
ILE A 172
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.53A 3uqbA-5xb0A:
16.8		 3uqbA-5xb0A:
31.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VAW_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN
SMT3,PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		6 / 11 PHE A 166
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.16A 3vawA-5xb0A:
15.7		 3vawA-5xb0A:
32.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VAW_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN
SMT3,PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 11 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.74A 3vawA-5xb0A:
15.7		 3vawA-5xb0A:
32.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRH_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 12 TYR A 147
ASP A 158
PHE A 166
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.12A 4drhA-5xb0A:
16.1		 4drhA-5xb0A:
30.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRH_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 12 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.75A 4drhA-5xb0A:
16.1		 4drhA-5xb0A:
30.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRH_D_RAPD201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		7 / 12 ASP A 158
PHE A 166
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 (-3.7A)
TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.16A 4drhD-5xb0A:
16.0		 4drhD-5xb0A:
30.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRH_D_RAPD201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 12 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.74A 4drhD-5xb0A:
16.0		 4drhD-5xb0A:
30.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRI_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 11 TYR A 147
ASP A 158
PHE A 166
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.04A 4driA-5xb0A:
16.6		 4driA-5xb0A:
30.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRI_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 11 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.66A 4driA-5xb0A:
16.6		 4driA-5xb0A:
30.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRJ_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 11 TYR A 147
ASP A 158
PHE A 166
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.05A 4drjA-5xb0A:
16.5		 4drjA-5xb0A:
31.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRJ_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 11 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.67A 4drjA-5xb0A:
16.5		 4drjA-5xb0A:
31.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_A_FK5A200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		6 / 11 PHE A 166
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.12A 4dz2A-5xb0A:
16.6
4dz2B-5xb0A:
16.6		 4dz2A-5xb0A:
37.50
4dz2B-5xb0A:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_A_FK5A200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 11 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.70A 4dz2A-5xb0A:
16.6
4dz2B-5xb0A:
16.6		 4dz2A-5xb0A:
37.50
4dz2B-5xb0A:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_B_FK5B200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		6 / 11 PHE A 166
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.12A 4dz2A-5xb0A:
16.6
4dz2B-5xb0A:
16.6		 4dz2A-5xb0A:
37.50
4dz2B-5xb0A:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_B_FK5B200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 11 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.67A 4dz2A-5xb0A:
16.6
4dz2B-5xb0A:
16.6		 4dz2A-5xb0A:
37.50
4dz2B-5xb0A:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ3_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		7 / 10 PHE A 166
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.06A 4dz3A-5xb0A:
16.6		 4dz3A-5xb0A:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ3_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 10 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.70A 4dz3A-5xb0A:
16.6		 4dz3A-5xb0A:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ3_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		7 / 10 PHE A 166
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.07A 4dz3B-5xb0A:
16.6		 4dz3B-5xb0A:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ3_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 10 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.72A 4dz3B-5xb0A:
16.6		 4dz3B-5xb0A:
37.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAX_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 10 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.68A 4laxA-5xb0A:
16.5		 4laxA-5xb0A:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAX_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		7 / 10 TYR A 147
PHE A 166
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.02A 4laxA-5xb0A:
16.5		 4laxA-5xb0A:
28.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NNR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		6 / 12 PHE A 166
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.11A 4nnrA-5xb0A:
12.1
4nnrB-5xb0A:
12.4		 4nnrA-5xb0A:
34.23
4nnrB-5xb0A:
34.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NNR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 12 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.69A 4nnrA-5xb0A:
12.1
4nnrB-5xb0A:
12.4		 4nnrA-5xb0A:
34.23
4nnrB-5xb0A:
34.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NNR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		6 / 10 PHE A 166
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.13A 4nnrB-5xb0A:
12.4		 4nnrB-5xb0A:
34.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NNR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 10 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.75A 4nnrB-5xb0A:
12.4		 4nnrB-5xb0A:
34.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 10 TYR A 147
ASP A 158
ILE A 172
TYR A 198
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
None
None
 0.70A 4odoA-5xb0A:
9.7		 4odoA-5xb0A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 10 TYR A 147
ASP A 158
ILE A 172
TYR A 198
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
None
None
 0.66A 4odoB-5xb0A:
9.4		 4odoB-5xb0A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_C_FK5C204_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 10 TYR A 147
ASP A 158
ILE A 172
TYR A 198
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
None
None
 0.70A 4odoC-5xb0A:
9.3		 4odoC-5xb0A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 11 TYR A 147
ASP A 158
ILE A 172
TYR A 198
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
None
None
 0.67A 4odrA-5xb0A:
10.9
4odrB-5xb0A:
11.0		 4odrA-5xb0A:
22.73
4odrB-5xb0A:
22.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QT2_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		7 / 10 ASP A 158
PHE A 166
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 (-3.7A)
TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.14A 4qt2A-5xb0A:
16.3		 4qt2A-5xb0A:
33.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QT2_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 10 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.72A 4qt2A-5xb0A:
16.3		 4qt2A-5xb0A:
33.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QT3_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 10 TYR A 147
ASP A 158
PHE A 166
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.06A 4qt3A-5xb0A:
15.6		 4qt3A-5xb0A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QT3_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 10 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.68A 4qt3A-5xb0A:
15.6		 4qt3A-5xb0A:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 4 GLY A  92
LEU A 151
PHE A 157
ILE A 207
 None
 0.89A 4xv2A-5xb0A:
undetectable		 4xv2A-5xb0A:
21.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B8I_C_FK5C201_3
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 12 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.68A 5b8iC-5xb0A:
15.2		 5b8iC-5xb0A:
31.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B8I_C_FK5C201_3
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		7 / 12 TYR A 147
PHE A 166
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.07A 5b8iC-5xb0A:
15.2		 5b8iC-5xb0A:
31.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 PHE A 215
ILE A 192
VAL A 171
GLY A 199
THR A 176
 None
None
TLA  A 301 (-3.4A)
None
None
 1.07A 5byjA-5xb0A:
undetectable		 5byjA-5xb0A:
19.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D75_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 11 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.59A 5d75A-5xb0A:
15.5		 5d75A-5xb0A:
31.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GPG_A_RAPA301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 11 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.64A 5gpgA-5xb0A:
15.9		 5gpgA-5xb0A:
31.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HKG_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1B)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		7 / 12 TYR A 147
ASP A 158
PHE A 166
ILE A 172
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
None
None
None
 1.12A 5hkgA-5xb0A:
15.0		 5hkgA-5xb0A:
29.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HKG_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1B)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		7 / 12 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.70A 5hkgA-5xb0A:
15.0		 5hkgA-5xb0A:
29.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HUA_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 11 PHE A 166
ILE A 172
TRP A 175
TYR A 198
PHE A 215
 TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
 1.13A 5huaA-5xb0A:
17.5		 5huaA-5xb0A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HUA_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		7 / 11 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
 0.61A 5huaA-5xb0A:
17.5		 5huaA-5xb0A:
30.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		7 / 11 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
 0.65A 5hw8A-5xb0A:
15.1
5hw8D-5xb0A:
15.2		 5hw8A-5xb0A:
27.94
5hw8D-5xb0A:
27.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_B_FK5B201_1
(FK506-BINDING
PROTEIN 1)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 11 PHE A 166
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
None
None
None
 1.14A 5hw8B-5xb0A:
15.1		 5hw8B-5xb0A:
27.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_B_FK5B201_1
(FK506-BINDING
PROTEIN 1)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		7 / 11 TYR A 147
ASP A 158
VAL A 171
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.63A 5hw8B-5xb0A:
15.1		 5hw8B-5xb0A:
27.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_B_FK5B201_1
(FK506-BINDING
PROTEIN 1)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 11 TYR A 147
VAL A 171
TRP A 175
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
 1.22A 5hw8B-5xb0A:
15.1		 5hw8B-5xb0A:
27.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_C_FK5C201_1
(FK506-BINDING
PROTEIN 1)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 10 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
LEU A 213
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.53A 5hw8C-5xb0A:
15.2
5hw8H-5xb0A:
12.8		 5hw8C-5xb0A:
27.94
5hw8H-5xb0A:
27.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_D_FK5D201_1
(FK506-BINDING
PROTEIN 1)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		6 / 11 PHE A 166
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.07A 5hw8D-5xb0A:
15.2		 5hw8D-5xb0A:
27.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_D_FK5D201_1
(FK506-BINDING
PROTEIN 1)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 11 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.67A 5hw8D-5xb0A:
15.2		 5hw8D-5xb0A:
27.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_E_FK5E201_1
(FK506-BINDING
PROTEIN 1)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 11 PHE A 166
ILE A 172
TRP A 175
TYR A 198
PHE A 215
 TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
 1.13A 5hw8E-5xb0A:
15.1		 5hw8E-5xb0A:
27.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_E_FK5E201_1
(FK506-BINDING
PROTEIN 1)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		7 / 11 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
 0.73A 5hw8E-5xb0A:
15.1		 5hw8E-5xb0A:
27.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_F_FK5F201_1
(FK506-BINDING
PROTEIN 1)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		7 / 12 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
 0.76A 5hw8B-5xb0A:
15.1
5hw8F-5xb0A:
12.2
5hw8G-5xb0A:
15.2		 5hw8B-5xb0A:
27.94
5hw8F-5xb0A:
27.94
5hw8G-5xb0A:
27.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_F_FK5F201_1
(FK506-BINDING
PROTEIN 1)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		6 / 12 TYR A 147
PHE A 166
ILE A 172
TRP A 175
TYR A 198
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
 1.03A 5hw8B-5xb0A:
15.1
5hw8F-5xb0A:
12.2
5hw8G-5xb0A:
15.2		 5hw8B-5xb0A:
27.94
5hw8F-5xb0A:
27.94
5hw8G-5xb0A:
27.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_2
(FK506-BINDING
PROTEIN 1)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		6 / 11 PHE A 166
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.06A 5hw8G-5xb0A:
15.2		 5hw8G-5xb0A:
27.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_2
(FK506-BINDING
PROTEIN 1)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 11 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.68A 5hw8G-5xb0A:
15.2		 5hw8G-5xb0A:
27.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_H_FK5H201_1
(FK506-BINDING
PROTEIN 1)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		6 / 8 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
 0.78A 5hw8H-5xb0A:
12.8		 5hw8H-5xb0A:
27.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HWC_A_FK5A201_1
(FK506-BINDING
PROTEIN 1A)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 11 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.68A 5hwcA-5xb0A:
16.1		 5hwcA-5xb0A:
31.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HWC_A_FK5A201_1
(FK506-BINDING
PROTEIN 1A)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		7 / 11 TYR A 147
PHE A 166
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.06A 5hwcA-5xb0A:
16.1		 5hwcA-5xb0A:
31.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_H_CVIH301_1
(REGULATORY PROTEIN
TETR)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 8 GLN A 180
GLY A 174
ILE A 217
TRP A 188
 None
 0.93A 5vlmH-5xb0A:
undetectable		 5vlmH-5xb0A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_A_FK5A201_0
(PEPTIDYLPROLYL
ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 12 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.65A 6mkeA-5xb0A:
16.7
6mkeD-5xb0A:
16.2		 6mkeA-5xb0A:
18.38
6mkeD-5xb0A:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_A_FK5A201_0
(PEPTIDYLPROLYL
ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		7 / 12 TYR A 147
PHE A 166
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.05A 6mkeA-5xb0A:
16.7
6mkeD-5xb0A:
16.2		 6mkeA-5xb0A:
18.38
6mkeD-5xb0A:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_B_FK5B201_0
(PEPTIDYLPROLYL
ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		6 / 12 PHE A 166
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.11A 6mkeB-5xb0A:
16.7
6mkeC-5xb0A:
16.4		 6mkeB-5xb0A:
18.38
6mkeC-5xb0A:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_B_FK5B201_0
(PEPTIDYLPROLYL
ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 12 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.64A 6mkeB-5xb0A:
16.7
6mkeC-5xb0A:
16.4		 6mkeB-5xb0A:
18.38
6mkeC-5xb0A:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_1
(PEPTIDYLPROLYL
ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		7 / 10 PHE A 166
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.01A 6mkeC-5xb0A:
16.4		 6mkeC-5xb0A:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_1
(PEPTIDYLPROLYL
ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 10 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.69A 6mkeC-5xb0A:
16.4		 6mkeC-5xb0A:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_1
(PEPTIDYLPROLYL
ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		7 / 10 PHE A 166
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.6A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 1.02A 6mkeD-5xb0A:
16.2		 6mkeD-5xb0A:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_1
(PEPTIDYLPROLYL
ISOMERASE)		 5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		8 / 10 TYR A 147
ASP A 158
VAL A 171
ILE A 172
TRP A 175
TYR A 198
ILE A 207
PHE A 215
 TLA  A 301 ( 4.4A)
TLA  A 301 (-3.7A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
TLA  A 301 (-3.4A)
None
None
None
 0.69A 6mkeD-5xb0A:
16.2		 6mkeD-5xb0A:
18.38