SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xb6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5xb6 UNCHARACTERIZED
PROTEIN YCJY
(Escherichia
coli) 		4 / 8 SER A 146
ARG A 149
ASN A 143
ASP A 261
 None
 0.98A 1p6kA-5xb6A:
undetectable		 1p6kA-5xb6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5xb6 UNCHARACTERIZED
PROTEIN YCJY
(Escherichia
coli) 		4 / 8 SER A 146
ARG A 149
ASN A 143
ASP A 261
 None
 0.88A 1p6kB-5xb6A:
undetectable		 1p6kB-5xb6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5xb6 UNCHARACTERIZED
PROTEIN YCJY
(Escherichia
coli) 		3 / 3 VAL A 142
ALA A 118
HIS A  41
 None
 0.68A 1q23G-5xb6A:
undetectable		 1q23G-5xb6A:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5xb6 UNCHARACTERIZED
PROTEIN YCJY
(Escherichia
coli) 		3 / 3 VAL A 142
ALA A 118
HIS A  41
 None
 0.72A 1q23L-5xb6A:
undetectable		 1q23L-5xb6A:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5xb6 UNCHARACTERIZED
PROTEIN YCJY
(Escherichia
coli) 		3 / 3 VAL A 142
ALA A 118
HIS A  41
 None
 0.69A 1q23J-5xb6A:
undetectable		 1q23J-5xb6A:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5xb6 UNCHARACTERIZED
PROTEIN YCJY
(Escherichia
coli) 		4 / 8 SER A 146
ARG A 149
ASN A 143
ASP A 261
 None
 1.04A 1rs6A-5xb6A:
undetectable		 1rs6A-5xb6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5xb6 UNCHARACTERIZED
PROTEIN YCJY
(Escherichia
coli) 		4 / 8 SER A 146
ARG A 149
ASN A 143
ASP A 261
 None
 0.90A 1rs6B-5xb6A:
undetectable		 1rs6B-5xb6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5xb6 UNCHARACTERIZED
PROTEIN YCJY
(Escherichia
coli) 		4 / 8 SER A 146
ARG A 149
ASN A 143
ASP A 261
 None
 0.85A 1rs7B-5xb6A:
undetectable		 1rs7B-5xb6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_0
(HYPOTHETICAL PROTEIN
PH0226)		 5xb6 UNCHARACTERIZED
PROTEIN YCJY
(Escherichia
coli) 		5 / 12 ALA A 141
GLY A 121
ILE A 247
ALA A 249
ILE A 147
 None
 1.17A 1ve3A-5xb6A:
undetectable		 1ve3A-5xb6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5xb6 UNCHARACTERIZED
PROTEIN YCJY
(Escherichia
coli) 		4 / 8 SER A 146
ARG A 149
ASN A 143
ASP A 261
 None
 1.00A 1zzqA-5xb6A:
undetectable		 1zzqA-5xb6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5xb6 UNCHARACTERIZED
PROTEIN YCJY
(Escherichia
coli) 		4 / 8 SER A 146
ARG A 149
ASN A 143
ASP A 261
 None
 0.89A 1zzqB-5xb6A:
undetectable		 1zzqB-5xb6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5xb6 UNCHARACTERIZED
PROTEIN YCJY
(Escherichia
coli) 		4 / 8 SER A 146
ARG A 149
ASN A 143
ASP A 261
 None
 0.86A 1zzuB-5xb6A:
undetectable		 1zzuB-5xb6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE)		 5xb6 UNCHARACTERIZED
PROTEIN YCJY
(Escherichia
coli) 		4 / 8 SER A 146
ARG A 149
ASN A 143
ASP A 261
 None
 1.32A 3n62A-5xb6A:
undetectable		 3n62A-5xb6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 5xb6 UNCHARACTERIZED
PROTEIN YCJY
(Escherichia
coli) 		4 / 8 SER A 146
ARG A 149
ASN A 143
ASP A 261
 None
 1.03A 3n62B-5xb6A:
undetectable		 3n62B-5xb6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 5xb6 UNCHARACTERIZED
PROTEIN YCJY
(Escherichia
coli) 		4 / 8 SER A 146
ARG A 149
ASN A 143
ASP A 261
 None
 1.28A 3n66B-5xb6A:
0.5		 3n66B-5xb6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 5xb6 UNCHARACTERIZED
PROTEIN YCJY
(Escherichia
coli) 		5 / 11 GLU A  84
GLY A 119
ALA A 118
ILE A 116
ALA A  51
 None
 1.22A 3nmuB-5xb6A:
undetectable
3nmuJ-5xb6A:
2.7		 3nmuB-5xb6A:
undetectable
3nmuJ-5xb6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA452_1
(CYTOCHROME P450
164A2)		 5xb6 UNCHARACTERIZED
PROTEIN YCJY
(Escherichia
coli) 		5 / 12 LEU A 262
ALA A 124
THR A 123
ASN A 125
LEU A  39
 None
 1.19A 3r9cA-5xb6A:
undetectable		 3r9cA-5xb6A:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA452_1
(CYTOCHROME P450
164A2)		 5xb6 UNCHARACTERIZED
PROTEIN YCJY
(Escherichia
coli) 		5 / 12 SER A 255
LEU A 262
ALA A 124
THR A 123
ASN A 125
 None
 0.96A 3r9cA-5xb6A:
undetectable		 3r9cA-5xb6A:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA1_A_08YA600_1
(CYTOCHROME P450 3A4)		 5xb6 UNCHARACTERIZED
PROTEIN YCJY
(Escherichia
coli) 		5 / 12 ASP A  98
ARG A 131
ARG A 132
THR A 101
THR A 245
 None
 1.31A 3ua1A-5xb6A:
undetectable		 3ua1A-5xb6A:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_1
(ADENOSINE KINASE)		 5xb6 UNCHARACTERIZED
PROTEIN YCJY
(Escherichia
coli) 		5 / 12 LEU A 199
GLY A  45
GLY A  44
ALA A 202
GLY A 119
 None
 1.01A 4n09B-5xb6A:
3.6		 4n09B-5xb6A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_1
(ADENOSINE KINASE)		 5xb6 UNCHARACTERIZED
PROTEIN YCJY
(Escherichia
coli) 		5 / 12 LEU A 199
GLY A  45
GLY A  44
ALA A 202
GLY A 119
 None
 0.99A 4n09D-5xb6A:
3.8		 4n09D-5xb6A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUC_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 5xb6 UNCHARACTERIZED
PROTEIN YCJY
(Escherichia
coli) 		5 / 12 ASN A  85
GLU A  91
TYR A  87
ILE A 128
GLN A 243
 None
 1.06A 4xucA-5xb6A:
2.8		 4xucA-5xb6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSA_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 5xb6 UNCHARACTERIZED
PROTEIN YCJY
(Escherichia
coli) 		5 / 12 ASN A  85
GLU A  91
TYR A  87
ILE A 128
GLN A 243
 None
 1.12A 5lsaA-5xb6A:
2.8		 5lsaA-5xb6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIH_A_8CVA201_1
(DIHYDROFOLATE
REDUCTASE)		 5xb6 UNCHARACTERIZED
PROTEIN YCJY
(Escherichia
coli) 		4 / 8 ILE A 144
ALA A 233
MET A 258
ILE A 147
 None
 0.89A 5uihA-5xb6A:
undetectable		 5uihA-5xb6A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_B_C2FB702_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5xb6 UNCHARACTERIZED
PROTEIN YCJY
(Escherichia
coli) 		4 / 5 ASN A  10
ASP A  92
ASN A  85
ARG A 172
 None
 1.21A 5vooB-5xb6A:
undetectable		 5vooB-5xb6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_D_C2FD3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5xb6 UNCHARACTERIZED
PROTEIN YCJY
(Escherichia
coli) 		4 / 5 ASN A  10
ASP A  92
ASN A  85
ARG A 172
 None
 1.20A 5vooD-5xb6A:
undetectable		 5vooD-5xb6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5xb6 UNCHARACTERIZED
PROTEIN YCJY
(Escherichia
coli) 		4 / 8 SER A 146
ARG A 149
ASN A 143
ASP A 261
 None
 1.35A 5vuoB-5xb6A:
undetectable		 5vuoB-5xb6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5xb6 UNCHARACTERIZED
PROTEIN YCJY
(Escherichia
coli) 		4 / 8 SER A 146
ARG A 149
ASN A 143
ASP A 261
 None
 1.31A 6auuB-5xb6A:
undetectable		 6auuB-5xb6A:
undetectable