SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xb7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_B_NCAB700_0
(EXOTOXIN A)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
4 / 6 HIS A 346
GLY A 360
TYR A  15
ALA A  13
None
0.92A 1dmaB-5xb7A:
undetectable
1dmaB-5xb7A:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_N_ACTN803_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
4 / 6 ARG A 300
GLY A 295
ASP A 297
TYR A 250
None
1.38A 1kf6M-5xb7A:
undetectable
1kf6N-5xb7A:
undetectable
1kf6M-5xb7A:
21.27
1kf6N-5xb7A:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_A_SAMA500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
4 / 7 PHE A 166
PHE A 200
SER A 206
ARG A 212
None
None
None
GOL  A 807 (-3.5A)
1.48A 1rqpB-5xb7A:
undetectable
1rqpB-5xb7A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_A_ADNA1501_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
4 / 7 GLU A 251
LYS A 153
PRO A 261
ALA A 262
None
1.30A 2ejgA-5xb7A:
undetectable
2ejgA-5xb7A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_B_ADNB1502_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
4 / 7 GLU A 251
LYS A 153
PRO A 261
ALA A 262
None
1.26A 2ejgB-5xb7A:
1.7
2ejgB-5xb7A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA996_1
(GLUCOAMYLASE GLU1)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
4 / 7 ARG A 300
ASP A 448
THR A 630
GLY A 629
None
0.90A 2f6dA-5xb7A:
undetectable
2f6dA-5xb7A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IJ7_C_TPFC2471_1
(CYTOCHROME P450 121)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
4 / 8 THR A 494
VAL A 591
ALA A 599
GLN A 594
None
1.16A 2ij7C-5xb7A:
undetectable
2ij7C-5xb7A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_1
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
4 / 5 PRO A 261
ALA A 262
ASP A 297
ASP A 249
None
1.11A 2nyuB-5xb7A:
undetectable
2nyuB-5xb7A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
5 / 12 LEU A 329
LEU A 335
ALA A 336
LEU A 640
CYH A 625
None
None
None
None
GOL  A 803 (-4.7A)
1.24A 2oaxB-5xb7A:
undetectable
2oaxB-5xb7A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_2
(PROTEASE RETROPEPSIN)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
5 / 12 GLY A 376
ALA A  37
GLY A 383
ILE A 382
ILE A  39
None
0.96A 2qhcB-5xb7A:
undetectable
2qhcB-5xb7A:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WX2_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
4 / 8 ALA A 404
ALA A 452
THR A 477
LEU A 481
None
1.03A 2wx2B-5xb7A:
undetectable
2wx2B-5xb7A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_X_CPFX1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
4 / 4 ARG A 328
GLY A 379
GLU A 381
SER A 368
None
1.31A 2xctS-5xb7A:
1.3
2xctU-5xb7A:
undetectable
2xctS-5xb7A:
23.85
2xctU-5xb7A:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1470_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
4 / 5 ARG A 601
ALA A 439
ASP A 438
GLU A 442
SO4  A 810 (-3.0A)
None
None
SO4  A 810 (-4.2A)
1.08A 2xrzA-5xb7A:
undetectable
2xrzA-5xb7A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_1
(PROTEASE)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
5 / 12 GLY A 338
ALA A 339
ASP A 340
GLY A 276
THR A 312
None
0.93A 3el4A-5xb7A:
undetectable
3el4A-5xb7A:
10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZ0_B_CLYB900_1
(LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
4 / 8 GLU A 446
TYR A 437
PHE A 449
SER A 301
None
0.73A 3jz0B-5xb7A:
undetectable
3jz0B-5xb7A:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KHM_A_TPFA501_1
(STEROL 14
ALPHA-DEMETHYLASE)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
4 / 8 ALA A 404
ALA A 452
THR A 477
LEU A 481
None
0.94A 3khmA-5xb7A:
undetectable
3khmA-5xb7A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_1
(HIV-1 PROTEASE)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
5 / 10 GLY A 376
ALA A  37
GLY A 383
ILE A 382
ILE A  39
None
0.96A 3ttpA-5xb7A:
undetectable
3ttpA-5xb7A:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_2
(HIV-1 PROTEASE)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
5 / 10 GLY A 376
ALA A  37
GLY A 383
ILE A 382
ILE A  39
None
0.97A 3ttpB-5xb7A:
undetectable
3ttpB-5xb7A:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
5 / 12 MET A 343
LEU A  68
GLY A 145
GLN A 147
ILE A 144
None
1.26A 4djeA-5xb7A:
10.0
4djeA-5xb7A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_1
(DIPEPTIDYL PEPTIDASE
4)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
5 / 12 GLY A 629
VAL A 277
TYR A 307
VAL A 309
HIS A 334
None
1.20A 4ffwA-5xb7A:
3.1
4ffwA-5xb7A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_1
(DIPEPTIDYL PEPTIDASE
4)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
5 / 12 GLY A 629
VAL A 277
TYR A 307
VAL A 309
HIS A 334
None
1.23A 4ffwB-5xb7A:
3.1
4ffwB-5xb7A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
4 / 4 SER A 256
LEU A 433
TYR A 250
PRO A 282
None
1.26A 4jksA-5xb7A:
3.3
4jksA-5xb7A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
4 / 4 SER A 256
LEU A 433
TYR A 250
PRO A 282
None
1.26A 4jksB-5xb7A:
3.1
4jksB-5xb7A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_2
(PROBABLE SUGAR
KINASE PROTEIN)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
4 / 4 SER A 256
LEU A 433
TYR A 250
PRO A 282
None
1.24A 4jkuA-5xb7A:
3.5
4jkuA-5xb7A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_2
(SUGAR KINASE)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
4 / 4 SER A 256
LEU A 433
TYR A 250
PRO A 282
None
1.28A 4k8cB-5xb7A:
undetectable
4k8cB-5xb7A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_2
(SUGAR KINASE)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
4 / 4 SER A 256
LEU A 433
TYR A 250
PRO A 282
None
1.26A 4k8kA-5xb7A:
undetectable
4k8kA-5xb7A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_2
(SUGAR KINASE)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
4 / 4 SER A 256
LEU A 433
TYR A 250
PRO A 282
None
1.26A 4k8kB-5xb7A:
undetectable
4k8kB-5xb7A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
4 / 4 SER A 256
LEU A 433
TYR A 250
PRO A 282
None
1.26A 4kalA-5xb7A:
3.1
4kalA-5xb7A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
4 / 4 SER A 256
LEU A 433
TYR A 250
PRO A 282
None
1.24A 4kalB-5xb7A:
3.1
4kalB-5xb7A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
4 / 4 SER A 256
LEU A 433
TYR A 250
PRO A 282
None
1.25A 4lcaA-5xb7A:
undetectable
4lcaA-5xb7A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
4 / 4 SER A 256
LEU A 433
TYR A 250
PRO A 282
None
1.23A 4lcaB-5xb7A:
undetectable
4lcaB-5xb7A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_A_MRVA1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
4 / 7 TYR A 429
GLN A 589
THR A 579
LEU A 555
None
0.91A 4mbsA-5xb7A:
undetectable
4mbsA-5xb7A:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_0
(HYDG PROTEIN)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
5 / 12 TYR A 484
VAL A 447
LEU A 491
LEU A 481
ALA A 454
None
1.34A 4rtbA-5xb7A:
7.7
4rtbA-5xb7A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_D_QI9D602_0
(CYTOCHROME P450 2D6)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
4 / 7 LEU A 391
THR A 699
VAL A 694
PHE A 658
None
0.85A 4wnvD-5xb7A:
undetectable
4wnvD-5xb7A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_2
(ESTROGEN RECEPTOR)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
4 / 6 LEU A 391
ASP A 384
GLU A 381
ILE A 693
None
1.05A 4xi3C-5xb7A:
undetectable
4xi3C-5xb7A:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
5 / 12 TYR A  16
ILE A 382
VAL A  78
GLY A 376
LEU A 361
None
1.28A 5esgA-5xb7A:
undetectable
5esgA-5xb7A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
5 / 12 SER A 497
LEU A 470
PRO A 468
VAL A 432
LEU A 403
None
0.98A 5jo9A-5xb7A:
2.6
5jo9A-5xb7A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
5 / 12 THR A 312
GLY A 316
ILE A 292
SER A 283
LEU A 327
None
0.76A 5l0zA-5xb7A:
undetectable
5l0zA-5xb7A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_B_SAMB304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
5 / 10 THR A 312
GLY A 316
ILE A 292
SER A 283
LEU A 327
None
0.88A 5l0zB-5xb7A:
undetectable
5l0zB-5xb7A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_A_PFLA412_1
(PROTON-GATED ION
CHANNEL)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
5 / 10 TYR A 280
ILE A 279
VAL A 277
TYR A 344
ILE A 342
None
1.31A 5mzrA-5xb7A:
undetectable
5mzrA-5xb7A:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
5 / 9 TYR A 280
ILE A 279
VAL A 277
TYR A 344
ILE A 342
None
1.31A 5mzrD-5xb7A:
undetectable
5mzrD-5xb7A:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_0
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
5 / 12 GLU A 553
GLY A 592
ALA A 548
ALA A 577
ALA A 565
None
0.83A 5zw4A-5xb7A:
undetectable
5zw4A-5xb7A:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
5 / 12 TYR A 344
TYR A 280
GLY A 360
ALA A 314
LEU A 327
None
1.00A 5zwrA-5xb7A:
undetectable
5zwrA-5xb7A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
4 / 6 TYR A  85
ASP A 278
GLN A 260
GLU A 311
None
GOL  A 802 (-4.2A)
None
GOL  A 802 (-2.4A)
1.48A 6djzA-5xb7A:
undetectable
6djzA-5xb7A:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_0
(CYTOCHROME P450 1A1)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
5 / 12 SER A 337
PHE A 441
ASN A 444
ASP A 438
ILE A 292
None
GOL  A 803 (-4.7A)
GOL  A 803 (-2.9A)
None
None
1.43A 6dwnB-5xb7A:
undetectable
6dwnB-5xb7A:
7.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_0
(CYTOCHROME P450 1A1)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
5 / 12 SER A 337
PHE A 441
LEU A 443
ASN A 444
ILE A 292
None
GOL  A 803 (-4.7A)
None
GOL  A 803 (-2.9A)
None
1.40A 6dwnB-5xb7A:
undetectable
6dwnB-5xb7A:
7.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_G_ZOLG401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
4 / 7 GLN A 113
LYS A 153
GLN A 260
TYR A 250
None
1.43A 6g31G-5xb7A:
undetectable
6g31G-5xb7A:
8.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)
5xb7 BETA-GALACTOSIDASE
(Bifidobacterium
animalis)
4 / 7 ILE A 117
GLU A 151
VAL A 223
TRP A 229
None
GOL  A 802 ( 3.2A)
None
None
1.07A 6j20A-5xb7A:
undetectable
6j20A-5xb7A:
20.91