SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xbc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 5xbc NSP1 PROTEIN
(Porcine
epidemic
diarrhea
virus) 		3 / 3 LEU A 110
VAL A  74
ARG A 107
 None
 0.85A 3b0wB-5xbcA:
undetectable		 3b0wB-5xbcA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_A_OBNA1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5xbc NSP1 PROTEIN
(Porcine
epidemic
diarrhea
virus) 		5 / 11 ASP A  50
VAL A  44
ALA A  10
THR A  51
ILE A  15
 None
 1.25A 3n23A-5xbcA:
undetectable		 3n23A-5xbcA:
6.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 5xbc NSP1 PROTEIN
(Porcine
epidemic
diarrhea
virus) 		4 / 8 GLU A  14
VAL A  44
GLY A  54
LEU A  55
 None
 1.06A 5sxqB-5xbcA:
undetectable		 5sxqB-5xbcA:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 5xbc NSP1 PROTEIN
(Porcine
epidemic
diarrhea
virus) 		4 / 8 GLU A  14
VAL A  44
GLY A  54
LEU A  55
 None
 1.06A 5syjA-5xbcA:
undetectable		 5syjA-5xbcA:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 5xbc NSP1 PROTEIN
(Porcine
epidemic
diarrhea
virus) 		5 / 12 LEU A  70
VAL A  64
GLY A  86
SER A  45
PHE A  96
 None
 1.36A 6a94A-5xbcA:
undetectable		 6a94A-5xbcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_1
(PROTEIN CYP51)		 5xbc NSP1 PROTEIN
(Porcine
epidemic
diarrhea
virus) 		5 / 12 PHE A 104
ALA A  72
ALA A  13
THR A  51
LEU A  48
 None
 1.32A 6aycA-5xbcA:
undetectable		 6aycA-5xbcA:
20.65