SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xbi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YGN_A_PCFA1179_1 (WNT INHIBITORY FACTOR 1)	5xbi	PROBABLE TRANSCRIPTIONAL REGULATOR (Pseudomonas aeruginosa)	4 / 5	ILE A 146 PHE A 225 PRO A 219 VAL A 125	81U A 500 (-3.7A) 81U A 500 ( 4.6A) 81U A 500 ( 4.2A) None	1.29A	2ygnA-5xbiA: undetectable	2ygnA-5xbiA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BWY_A_SAMA301_0 (COMT PROTEIN)	5xbi	PROBABLE TRANSCRIPTIONAL REGULATOR (Pseudomonas aeruginosa)	5 / 12	GLU A 247 TYR A 266 ILE A 228 SER A 224 HIS A 214	81U A 500 (-3.1A) None None None None	1.46A	3bwyA-5xbiA: undetectable	3bwyA-5xbiA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X5I_A_FOLA201_1 (DIHYDROFOLATE REDUCTASE)	5xbi	PROBABLE TRANSCRIPTIONAL REGULATOR (Pseudomonas aeruginosa)	3 / 3	ASP A 165 ARG A 123 ARG A 252	None	0.87A	4x5iA-5xbiA: undetectable	4x5iA-5xbiA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EAJ_B_FOLB201_1 (DIHYDROFOLATE REDUCTASE)	5xbi	PROBABLE TRANSCRIPTIONAL REGULATOR (Pseudomonas aeruginosa)	3 / 3	ASP A 165 ARG A 123 ARG A 252	None	0.93A	5eajB-5xbiA: undetectable	5eajB-5xbiA: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2YGN_A_PCFA1179_1","WNT INHIBITORY FACTOR 1","5xbi","PROBABLE TRANSCRIPTIONAL REGULATOR","Pseudomonas aeruginosa",4,"ILE A 146;PHE A 225;PRO A 219;VAL A 125","81U A 500 (-3.7A);81U A 500 ( 4.6A);81U A 500 ( 4.2A);None","1.29A","2ygnA-5xbiA:undetectable","2ygnA-5xbiA:undetectable"],["3BWY_A_SAMA301_0","COMT PROTEIN","5xbi","PROBABLE TRANSCRIPTIONAL REGULATOR","Pseudomonas aeruginosa",5,"GLU A 247;TYR A 266;ILE A 228;SER A 224;HIS A 214","81U A 500 (-3.1A);None;None;None;None","1.46A","3bwyA-5xbiA:undetectable","3bwyA-5xbiA:undetectable"],["4X5I_A_FOLA201_1","DIHYDROFOLATE REDUCTASE","5xbi","PROBABLE TRANSCRIPTIONAL REGULATOR","Pseudomonas aeruginosa",3,"ASP A 165;ARG A 123;ARG A 252","None","0.87A","4x5iA-5xbiA:undetectable","4x5iA-5xbiA:undetectable"],["5EAJ_B_FOLB201_1","DIHYDROFOLATE REDUCTASE","5xbi","PROBABLE TRANSCRIPTIONAL REGULATOR","Pseudomonas aeruginosa",3,"ASP A 165;ARG A 123;ARG A 252","None","0.93A","5eajB-5xbiA:undetectable","5eajB-5xbiA:undetectable"]]