SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xbj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E3V_A_DXCA801_0
(STEROID
DELTA-ISOMERASE)		 5xbj FLAGELLAR
HOOK-ASSOCIATED
PROTEIN FLGK
(Campylobacter
jejuni) 		5 / 12 TYR A 517
GLY A 370
VAL A 361
LEU A 360
ALA A 461
 None
 1.26A 1e3vA-5xbjA:
undetectable		 1e3vA-5xbjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J3J_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5xbj FLAGELLAR
HOOK-ASSOCIATED
PROTEIN FLGK
(Campylobacter
jejuni) 		5 / 10 ILE A 391
ASP A 453
PHE A 458
ILE A 441
ILE A 400
 None
 1.25A 1j3jA-5xbjA:
undetectable		 1j3jA-5xbjA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_1
(HEMK PROTEIN)		 5xbj FLAGELLAR
HOOK-ASSOCIATED
PROTEIN FLGK
(Campylobacter
jejuni) 		4 / 4 THR A 366
GLY A 470
ASP A 475
ALA A 327
 None
 1.02A 1sg9A-5xbjA:
undetectable		 1sg9A-5xbjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_A_J01A1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 5xbj FLAGELLAR
HOOK-ASSOCIATED
PROTEIN FLGK
(Campylobacter
jejuni) 		5 / 12 LEU A 113
ILE A 331
VAL A 147
LEU A 509
TYR A 116
 None
 1.14A 2japA-5xbjA:
undetectable		 2japA-5xbjA:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5xbj FLAGELLAR
HOOK-ASSOCIATED
PROTEIN FLGK
(Campylobacter
jejuni) 		4 / 8 THR A 285
ASP A 283
SER A 271
TYR A 304
 None
 1.26A 2xz5A-5xbjA:
undetectable
2xz5C-5xbjA:
undetectable		 2xz5A-5xbjA:
undetectable
2xz5C-5xbjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YZQ_A_SAMA6075_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN PH1780)		 5xbj FLAGELLAR
HOOK-ASSOCIATED
PROTEIN FLGK
(Campylobacter
jejuni) 		5 / 12 ILE A 272
ARG A 302
VAL A 169
ILE A 172
ILE A 245
 None
 1.13A 2yzqA-5xbjA:
undetectable		 2yzqA-5xbjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		 5xbj FLAGELLAR
HOOK-ASSOCIATED
PROTEIN FLGK
(Campylobacter
jejuni) 		5 / 9 TYR A  89
ILE A 316
ILE A 315
VAL A 161
TYR A  86
 None
 1.21A 3p4wA-5xbjA:
3.3		 3p4wA-5xbjA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB665_1
(ALPHA-GLUCOSIDASE)		 5xbj FLAGELLAR
HOOK-ASSOCIATED
PROTEIN FLGK
(Campylobacter
jejuni) 		4 / 6 LYS A 383
ASP A 382
TYR A 377
LYS A 380
 None
 1.32A 3pocB-5xbjA:
undetectable		 3pocB-5xbjA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGT_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5xbj FLAGELLAR
HOOK-ASSOCIATED
PROTEIN FLGK
(Campylobacter
jejuni) 		5 / 10 ILE A 391
ASP A 453
PHE A 458
ILE A 441
ILE A 400
 None
 1.21A 3qgtA-5xbjA:
undetectable		 3qgtA-5xbjA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_2
(PROTEASE)		 5xbj FLAGELLAR
HOOK-ASSOCIATED
PROTEIN FLGK
(Campylobacter
jejuni) 		5 / 11 LEU A 360
ALA A 461
ILE A 451
ILE A 391
ILE A 367
 None
 0.84A 3s45B-5xbjA:
undetectable		 3s45B-5xbjA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_B_06XB501_1
(CYTOCHROME P450 2B6)		 5xbj FLAGELLAR
HOOK-ASSOCIATED
PROTEIN FLGK
(Campylobacter
jejuni) 		4 / 7 ILE A 451
ILE A 389
SER A 348
LEU A 360
 None
 0.88A 3ua5B-5xbjA:
0.0		 3ua5B-5xbjA:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UM5_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5xbj FLAGELLAR
HOOK-ASSOCIATED
PROTEIN FLGK
(Campylobacter
jejuni) 		5 / 10 ILE A 391
ASP A 453
PHE A 458
ILE A 441
ILE A 400
 None
 1.28A 3um5A-5xbjA:
undetectable		 3um5A-5xbjA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_2
(ADENOSINE KINASE)		 5xbj FLAGELLAR
HOOK-ASSOCIATED
PROTEIN FLGK
(Campylobacter
jejuni) 		4 / 5 ILE A 400
ALA A 459
MET A 397
PHE A 372
 None
 0.96A 4dc3B-5xbjA:
undetectable		 4dc3B-5xbjA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_F_ASWF101_1
(DNA TOPOISOMERASE
2-BETA)		 5xbj FLAGELLAR
HOOK-ASSOCIATED
PROTEIN FLGK
(Campylobacter
jejuni) 		4 / 6 ARG A 201
ALA A 219
GLU A 208
GLN A 185
 None
 0.88A 4g0uA-5xbjA:
undetectable		 4g0uA-5xbjA:
6.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_1
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)		 5xbj FLAGELLAR
HOOK-ASSOCIATED
PROTEIN FLGK
(Campylobacter
jejuni) 		4 / 6 ASN A 117
LEU A 113
GLU A 529
TYR A 511
 None
 1.16A 4wcxC-5xbjA:
2.6		 4wcxC-5xbjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5H_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5xbj FLAGELLAR
HOOK-ASSOCIATED
PROTEIN FLGK
(Campylobacter
jejuni) 		5 / 12 ILE A 245
THR A 168
ILE A 165
ARG A 300
LEU A 297
 None
 1.14A 4x5hA-5xbjA:
undetectable		 4x5hA-5xbjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 5xbj FLAGELLAR
HOOK-ASSOCIATED
PROTEIN FLGK
(Campylobacter
jejuni) 		5 / 12 ILE A 245
THR A 168
ILE A 165
ARG A 300
LEU A 297
 None
 1.09A 5e8qB-5xbjA:
undetectable		 5e8qB-5xbjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_A_SAMA801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 5xbj FLAGELLAR
HOOK-ASSOCIATED
PROTEIN FLGK
(Campylobacter
jejuni) 		5 / 12 ILE A 272
THR A 168
ASP A 170
PHE A 256
LEU A 284
 None
 1.17A 5hw4A-5xbjA:
undetectable		 5hw4A-5xbjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_C_SAMC801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 5xbj FLAGELLAR
HOOK-ASSOCIATED
PROTEIN FLGK
(Campylobacter
jejuni) 		5 / 12 ILE A 272
THR A 168
ASP A 170
PHE A 256
LEU A 284
 None
 1.11A 5hw4C-5xbjA:
undetectable		 5hw4C-5xbjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 5xbj FLAGELLAR
HOOK-ASSOCIATED
PROTEIN FLGK
(Campylobacter
jejuni) 		5 / 10 TYR A  89
ILE A 316
ILE A 315
VAL A 161
TYR A  86
 None
 1.08A 5mvnD-5xbjA:
3.3		 5mvnD-5xbjA:
24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UJX_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 5xbj FLAGELLAR
HOOK-ASSOCIATED
PROTEIN FLGK
(Campylobacter
jejuni) 		5 / 12 ILE A 245
THR A 168
ILE A 165
ARG A 300
LEU A 297
 None
 1.14A 5ujxB-5xbjA:
undetectable		 5ujxB-5xbjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5xbj FLAGELLAR
HOOK-ASSOCIATED
PROTEIN FLGK
(Campylobacter
jejuni) 		4 / 5 ARG A 402
MET A 397
THR A 396
LEU A 360
 None
 1.21A 5x1bW-5xbjA:
undetectable		 5x1bW-5xbjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5xbj FLAGELLAR
HOOK-ASSOCIATED
PROTEIN FLGK
(Campylobacter
jejuni) 		4 / 5 ARG A 402
MET A 397
THR A 396
LEU A 360
 None
 1.27A 5x1fW-5xbjA:
undetectable		 5x1fW-5xbjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EF6_A_BEZA401_0
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 5xbj FLAGELLAR
HOOK-ASSOCIATED
PROTEIN FLGK
(Campylobacter
jejuni) 		5 / 9 LEU A 297
THR A 285
ILE A 272
VAL A 169
ILE A 165
 None
 1.24A 6ef6A-5xbjA:
0.3		 6ef6A-5xbjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5xbj FLAGELLAR
HOOK-ASSOCIATED
PROTEIN FLGK
(Campylobacter
jejuni) 		4 / 5 ARG A 402
MET A 397
THR A 396
LEU A 360
 None
 1.35A 6nknJ-5xbjA:
undetectable		 6nknJ-5xbjA:
undetectable