SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xbn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 5xbn WSS1P
(Saccharomyces
cerevisiae) 		4 / 5 HIS A 115
GLU A 116
HIS A 119
HIS A 125
 ZN  A 201 (-3.2A)
ZN  A 201 ( 4.7A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.2A)
 0.28A 1os2A-5xbnA:
3.2		 1os2A-5xbnA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 5xbn WSS1P
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 115
GLU A 116
HIS A 119
HIS A 125
 ZN  A 201 (-3.2A)
ZN  A 201 ( 4.7A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.2A)
 0.25A 1os2D-5xbnA:
3.4		 1os2D-5xbnA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R55_A_097A518_1
(ADAM 33)		 5xbn WSS1P
(Saccharomyces
cerevisiae) 		5 / 10 THR A 112
HIS A 115
GLU A 116
HIS A 119
HIS A 125
 None
ZN  A 201 (-3.2A)
ZN  A 201 ( 4.7A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.2A)
 0.30A 1r55A-5xbnA:
4.5		 1r55A-5xbnA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 5xbn WSS1P
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 115
GLU A 116
HIS A 119
HIS A 125
 ZN  A 201 (-3.2A)
ZN  A 201 ( 4.7A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.2A)
 0.29A 1uttA-5xbnA:
5.0		 1uttA-5xbnA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 5xbn WSS1P
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 115
GLU A 116
HIS A 119
HIS A 125
 ZN  A 201 (-3.2A)
ZN  A 201 ( 4.7A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.2A)
 0.30A 1utzA-5xbnA:
5.0		 1utzA-5xbnA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 5xbn WSS1P
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 115
GLU A 116
HIS A 119
HIS A 125
 ZN  A 201 (-3.2A)
ZN  A 201 ( 4.7A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.2A)
 0.30A 1utzB-5xbnA:
5.0		 1utzB-5xbnA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 5xbn WSS1P
(Saccharomyces
cerevisiae) 		4 / 6 HIS A 115
GLU A 116
HIS A 119
HIS A 125
 ZN  A 201 (-3.2A)
ZN  A 201 ( 4.7A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.2A)
 0.26A 1y93A-5xbnA:
5.0		 1y93A-5xbnA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 5xbn WSS1P
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 115
GLU A 116
HIS A 119
HIS A 125
 ZN  A 201 (-3.2A)
ZN  A 201 ( 4.7A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.2A)
 0.24A 2hu6A-5xbnA:
5.0		 2hu6A-5xbnA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 5xbn WSS1P
(Saccharomyces
cerevisiae) 		6 / 9 LEU A  80
THR A 112
HIS A 115
GLU A 116
HIS A 119
HIS A 125
 None
None
ZN  A 201 (-3.2A)
ZN  A 201 ( 4.7A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.2A)
 0.29A 2jihA-5xbnA:
4.2		 2jihA-5xbnA:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_B_097B1001_1
(ADAMTS-1)		 5xbn WSS1P
(Saccharomyces
cerevisiae) 		6 / 8 LEU A  80
THR A 112
HIS A 115
GLU A 116
HIS A 119
HIS A 125
 None
None
ZN  A 201 (-3.2A)
ZN  A 201 ( 4.7A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.2A)
 0.32A 2jihB-5xbnA:
4.1		 2jihB-5xbnA:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 5xbn WSS1P
(Saccharomyces
cerevisiae) 		5 / 6 LEU A  79
HIS A 115
GLU A 116
HIS A 119
HIS A 125
 None
ZN  A 201 (-3.2A)
ZN  A 201 ( 4.7A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.2A)
 0.64A 2ow9A-5xbnA:
3.7		 2ow9A-5xbnA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 5xbn WSS1P
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 115
GLU A 116
HIS A 119
HIS A 125
 ZN  A 201 (-3.2A)
ZN  A 201 ( 4.7A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.2A)
 0.36A 2ow9B-5xbnA:
4.8		 2ow9B-5xbnA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 5xbn WSS1P
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 115
GLU A 116
HIS A 119
HIS A 125
 ZN  A 201 (-3.2A)
ZN  A 201 ( 4.7A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.2A)
 0.39A 2ozrC-5xbnA:
4.6		 2ozrC-5xbnA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 5xbn WSS1P
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 115
GLU A 116
HIS A 119
HIS A 125
 ZN  A 201 (-3.2A)
ZN  A 201 ( 4.7A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.2A)
 0.42A 2ozrD-5xbnA:
4.7		 2ozrD-5xbnA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 5xbn WSS1P
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 115
GLU A 116
HIS A 119
HIS A 125
 ZN  A 201 (-3.2A)
ZN  A 201 ( 4.7A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.2A)
 0.43A 2ozrE-5xbnA:
3.6		 2ozrE-5xbnA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 5xbn WSS1P
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 115
HIS A 119
HIS A 125
 ZN  A 201 (-3.2A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.2A)
 0.27A 2ozrF-5xbnA:
3.7		 2ozrF-5xbnA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 5xbn WSS1P
(Saccharomyces
cerevisiae) 		6 / 9 LEU A  80
THR A 112
HIS A 115
GLU A 116
HIS A 119
HIS A 125
 None
None
ZN  A 201 (-3.2A)
ZN  A 201 ( 4.7A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.2A)
 0.30A 3hy7A-5xbnA:
3.9		 3hy7A-5xbnA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 5xbn WSS1P
(Saccharomyces
cerevisiae) 		5 / 9 ASP A  76
THR A 112
HIS A 115
GLU A 116
HIS A 119
 None
None
ZN  A 201 (-3.2A)
ZN  A 201 ( 4.7A)
ZN  A 201 (-3.3A)
 0.91A 3hy7B-5xbnA:
4.6		 3hy7B-5xbnA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 5xbn WSS1P
(Saccharomyces
cerevisiae) 		6 / 9 LEU A  80
THR A 112
HIS A 115
GLU A 116
HIS A 119
HIS A 125
 None
None
ZN  A 201 (-3.2A)
ZN  A 201 ( 4.7A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.2A)
 0.30A 3hy7B-5xbnA:
4.6		 3hy7B-5xbnA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 5xbn WSS1P
(Saccharomyces
cerevisiae) 		5 / 5 LEU A  79
HIS A 115
GLU A 116
HIS A 119
HIS A 125
 None
ZN  A 201 (-3.2A)
ZN  A 201 ( 4.7A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.2A)
 0.70A 3kecA-5xbnA:
3.7		 3kecA-5xbnA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_B_HAEB271_1
(COLLAGENASE 3)		 5xbn WSS1P
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 115
GLU A 116
HIS A 119
 ZN  A 201 (-3.2A)
ZN  A 201 ( 4.7A)
ZN  A 201 (-3.3A)
 0.15A 3kecB-5xbnA:
4.7		 3kecB-5xbnA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 5xbn WSS1P
(Saccharomyces
cerevisiae) 		4 / 5 HIS A 115
GLU A 116
HIS A 119
HIS A 125
 ZN  A 201 (-3.2A)
ZN  A 201 ( 4.7A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.2A)
 0.26A 3likA-5xbnA:
5.1		 3likA-5xbnA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 5xbn WSS1P
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 115
GLU A 116
HIS A 119
HIS A 125
 ZN  A 201 (-3.2A)
ZN  A 201 ( 4.7A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.2A)
 0.26A 3lilA-5xbnA:
3.4		 3lilA-5xbnA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 5xbn WSS1P
(Saccharomyces
cerevisiae) 		4 / 5 HIS A 115
GLU A 116
HIS A 119
HIS A 125
 ZN  A 201 (-3.2A)
ZN  A 201 ( 4.7A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.2A)
 0.21A 3ljgA-5xbnA:
3.8		 3ljgA-5xbnA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 5xbn WSS1P
(Saccharomyces
cerevisiae) 		4 / 5 HIS A 115
GLU A 116
HIS A 119
HIS A 125
 ZN  A 201 (-3.2A)
ZN  A 201 ( 4.7A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.2A)
 0.29A 3lkaA-5xbnA:
5.0		 3lkaA-5xbnA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 5xbn WSS1P
(Saccharomyces
cerevisiae) 		4 / 6 HIS A 115
GLU A 116
HIS A 119
HIS A 125
 ZN  A 201 (-3.2A)
ZN  A 201 ( 4.7A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.2A)
 0.47A 4a7bA-5xbnA:
4.8		 4a7bA-5xbnA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 5xbn WSS1P
(Saccharomyces
cerevisiae) 		4 / 6 LEU A  79
HIS A 115
GLU A 116
HIS A 119
 None
ZN  A 201 (-3.2A)
ZN  A 201 ( 4.7A)
ZN  A 201 (-3.3A)
 0.64A 4a7bA-5xbnA:
4.8		 4a7bA-5xbnA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_B_HAEB1270_1
(COLLAGENASE 3)		 5xbn WSS1P
(Saccharomyces
cerevisiae) 		4 / 5 LEU A  79
HIS A 115
GLU A 116
HIS A 119
 None
ZN  A 201 (-3.2A)
ZN  A 201 ( 4.7A)
ZN  A 201 (-3.3A)
 0.44A 4a7bB-5xbnA:
4.6		 4a7bB-5xbnA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_B_SALB801_1
(PROTEIN POLYBROMO-1)		 5xbn WSS1P
(Saccharomyces
cerevisiae) 		4 / 5 LEU A 117
ALA A  52
ASN A  26
ILE A  29
 None
 1.18A 4y03B-5xbnA:
2.6		 4y03B-5xbnA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 5xbn WSS1P
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 115
GLU A 116
HIS A 119
HIS A 125
 ZN  A 201 (-3.2A)
ZN  A 201 ( 4.7A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.2A)
 0.27A 5n5jA-5xbnA:
5.0		 5n5jA-5xbnA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 5xbn WSS1P
(Saccharomyces
cerevisiae) 		4 / 5 HIS A 115
GLU A 116
HIS A 119
HIS A 125
 ZN  A 201 (-3.2A)
ZN  A 201 ( 4.7A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.2A)
 0.28A 5n5kA-5xbnA:
5.0		 5n5kA-5xbnA:
21.74