SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xd0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AL4_A_DVAA6_0
(GRAMICIDIN D)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		4 / 5 ALA A 103
VAL A 105
TRP A 407
TRP A  66
 None
 1.46A 1al4A-5xd0A:
undetectable
1al4B-5xd0A:
undetectable		 1al4A-5xd0A:
2.49
1al4B-5xd0A:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ALZ_A_DVAA6_0
(ILE-GRAMICIDIN C
VAL-GRAMICIDIN A)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		4 / 4 ALA A 103
VAL A 105
TRP A 407
TRP A  66
 None
 1.46A 1alzA-5xd0A:
undetectable
1alzB-5xd0A:
undetectable		 1alzA-5xd0A:
2.70
1alzB-5xd0A:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EA1_A_TPFA470_1
(CYTOCHROME P450
51-LIKE RV0764C)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		4 / 8 PHE A 231
ARG A 302
THR A 247
LEU A 203
 None
 1.24A 1ea1A-5xd0A:
undetectable		 1ea1A-5xd0A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		3 / 3 ALA A 238
VAL A 243
TRP A 201
 None
 0.89A 1jnoA-5xd0A:
undetectable		 1jnoA-5xd0A:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		3 / 3 ALA A 238
VAL A 243
TRP A 201
 None
 0.89A 1jnoB-5xd0A:
undetectable		 1jnoB-5xd0A:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		3 / 3 ALA A 238
VAL A 243
TRP A 201
 None
 0.90A 1jo3A-5xd0A:
undetectable		 1jo3A-5xd0A:
3.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		3 / 3 ALA A 238
VAL A 243
TRP A 201
 None
 0.90A 1jo3B-5xd0A:
undetectable		 1jo3B-5xd0A:
3.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		3 / 3 ALA A 238
VAL A 243
TRP A 201
 None
 0.92A 1jo4A-5xd0A:
undetectable		 1jo4A-5xd0A:
3.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		3 / 3 ALA A 238
VAL A 243
TRP A 201
 None
 0.92A 1jo4B-5xd0A:
undetectable		 1jo4B-5xd0A:
3.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		3 / 3 ALA A 241
VAL A 243
TRP A 201
 None
 0.93A 1magA-5xd0A:
undetectable		 1magA-5xd0A:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		3 / 3 ALA A 241
VAL A 243
TRP A 201
 None
 0.94A 1magB-5xd0A:
undetectable		 1magB-5xd0A:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		3 / 3 ALA A 238
VAL A 243
TRP A 201
 None
 0.91A 1ng8A-5xd0A:
undetectable		 1ng8A-5xd0A:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		3 / 3 ALA A 238
VAL A 243
TRP A 201
 None
 0.91A 1ng8B-5xd0A:
undetectable		 1ng8B-5xd0A:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		3 / 3 ALA A 241
VAL A 243
TRP A 201
 None
 0.85A 1nrmA-5xd0A:
undetectable		 1nrmA-5xd0A:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		3 / 3 ALA A 241
VAL A 243
TRP A 201
 None
 0.85A 1nrmB-5xd0A:
undetectable		 1nrmB-5xd0A:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		3 / 3 ALA A 238
VAL A 243
TRP A 201
 None
 0.85A 1nruA-5xd0A:
undetectable		 1nruA-5xd0A:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		3 / 3 ALA A 238
VAL A 243
TRP A 201
 None
 0.84A 1nruB-5xd0A:
undetectable		 1nruB-5xd0A:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_A_DVAA6_0
(GRAMICIDIN A)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		3 / 3 ALA A 241
VAL A 243
TRP A 201
 None
 0.89A 1nt5A-5xd0A:
undetectable		 1nt5A-5xd0A:
2.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_B_DVAB6_0
(GRAMICIDIN A)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		3 / 3 ALA A 241
VAL A 243
TRP A 201
 None
 0.89A 1nt5B-5xd0A:
undetectable		 1nt5B-5xd0A:
2.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_A_DVAA6_0
(GRAMICIDIN C)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		3 / 3 ALA A 241
VAL A 243
TRP A 201
 None
 0.81A 1nt6A-5xd0A:
undetectable		 1nt6A-5xd0A:
2.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_B_DVAB6_0
(GRAMICIDIN C)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		3 / 3 ALA A 241
VAL A 243
TRP A 201
 None
 0.81A 1nt6B-5xd0A:
undetectable		 1nt6B-5xd0A:
2.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SS4_A_ACTA411_0
(GLYOXALASE FAMILY
PROTEIN)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		4 / 5 TRP A 139
VAL A  93
THR A  92
GLN A 141
 None
 1.47A 1ss4A-5xd0A:
undetectable		 1ss4A-5xd0A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_A_SC2A1290_1
(FICOLIN-2)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		4 / 5 ASP A 158
LEU A 205
GLY A 206
ARG A 219
 None
None
None
PGE  A 501 ( 4.9A)
 0.91A 2j2pA-5xd0A:
undetectable
2j2pB-5xd0A:
undetectable		 2j2pA-5xd0A:
21.87
2j2pB-5xd0A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1291_1
(FICOLIN-2)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		4 / 4 ASP A 158
LEU A 205
GLY A 206
ARG A 219
 None
None
None
PGE  A 501 ( 4.9A)
 0.96A 2j2pD-5xd0A:
undetectable
2j2pE-5xd0A:
undetectable		 2j2pD-5xd0A:
21.87
2j2pE-5xd0A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA6_0
(GRAMICIDIN A)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		4 / 5 ALA A 103
VAL A 105
TRP A 407
TRP A  66
 None
 1.45A 2xdcA-5xd0A:
undetectable
2xdcB-5xd0A:
undetectable		 2xdcA-5xd0A:
2.49
2xdcB-5xd0A:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB6_0
(GRAMICIDIN A)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		4 / 5 TRP A 407
TRP A  66
ALA A 103
VAL A 105
 None
 1.45A 2xdcA-5xd0A:
undetectable
2xdcB-5xd0A:
undetectable		 2xdcA-5xd0A:
2.49
2xdcB-5xd0A:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA6_0
(VAL-GRAMICIDIN A)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		4 / 5 ALA A 103
VAL A 105
TRP A 407
TRP A  66
 None
 1.40A 2y5mA-5xd0A:
undetectable
2y5mB-5xd0A:
undetectable		 2y5mA-5xd0A:
2.49
2y5mB-5xd0A:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_B_DVAB6_0
(VAL-GRAMICIDIN A)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		4 / 5 TRP A 407
TRP A  66
ALA A 103
VAL A 105
 None
 1.40A 2y5mA-5xd0A:
undetectable
2y5mB-5xd0A:
undetectable		 2y5mA-5xd0A:
2.49
2y5mB-5xd0A:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA6_0
(VAL-GRAMICIDIN A)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		4 / 5 ALA A 103
VAL A 105
TRP A 407
TRP A  66
 None
 1.41A 2y6nA-5xd0A:
undetectable
2y6nB-5xd0A:
undetectable		 2y6nA-5xd0A:
2.49
2y6nB-5xd0A:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB6_0
(VAL-GRAMICIDIN A)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		4 / 5 TRP A 407
TRP A  66
ALA A 103
VAL A 105
 None
 1.42A 2y6nA-5xd0A:
undetectable
2y6nB-5xd0A:
undetectable		 2y6nA-5xd0A:
2.49
2y6nB-5xd0A:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_A_ACTA700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		4 / 6 GLY A 157
TYR A 125
GLY A  98
MET A 101
 None
 0.97A 3e9rA-5xd0A:
undetectable		 3e9rA-5xd0A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_C_ACTC700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		4 / 6 GLY A 157
TYR A 125
GLY A  98
MET A 101
 None
 0.95A 3e9rC-5xd0A:
undetectable		 3e9rC-5xd0A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NAI_A_URFA521_1
(RNA DEPENDENT RNA
POLYMERASE)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		4 / 5 ARG A 219
ASP A 158
ASP A 195
ASP A 207
 PGE  A 501 ( 4.9A)
None
None
None
 1.33A 3naiA-5xd0A:
1.5		 3naiA-5xd0A:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA270_0
(PROTEIN SSM1)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		4 / 5 LEU A 254
SER A 259
LEU A 265
PRO A 266
 None
 1.03A 3onnA-5xd0A:
undetectable		 3onnA-5xd0A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG9_B_KANB305_1
(APH(2'')-ID)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		5 / 8 ASN A 132
ASP A 158
SER A  94
ASP A 195
GLU A 285
 None
None
PGE  A 501 ( 4.9A)
None
PGE  A 501 ( 4.4A)
 1.36A 3sg9B-5xd0A:
undetectable		 3sg9B-5xd0A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		5 / 12 GLY A 354
GLU A 387
TYR A 341
ASN A 336
ASN A 333
 None
 1.26A 4pb1A-5xd0A:
undetectable		 4pb1A-5xd0A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_2
(CDL2.3A)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		4 / 8 ILE A 250
MET A 192
LEU A 228
LEU A 265
 None
 0.99A 5ieoA-5xd0A:
undetectable		 5ieoA-5xd0A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_2
(SCRFP-TAG,GP41)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		3 / 3 LYS A  65
TRP A  66
SER A  68
 None
 1.30A 5nwwA-5xd0A:
undetectable		 5nwwA-5xd0A:
8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 5xd0 GLUCANASE
(Paenibacillus
sp.
X4) 		5 / 12 TYR A 292
LEU A 264
THR A 381
VAL A 377
TRP A 373
 None
 1.07A 6djzB-5xd0A:
undetectable		 6djzB-5xd0A:
21.23