SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xd7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1BX4_A_ADNA350_2 (PROTEIN (ADENOSINE KINASE))	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	3 / 3	LEU A 318 SER A 308 ASN A 133	None	0.69A	1bx4A-5xd7A: undetectable	1bx4A-5xd7A: 22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTN_O_TRPO81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	5 / 10	HIS A 306 ALA A 287 HIS A 300 THR A 299 ALA A 286	None None ACY A 403 (-4.1A) None None	1.17A	1gtnO-5xd7A: undetectable 1gtnP-5xd7A: undetectable	1gtnO-5xd7A: 11.52 1gtnP-5xd7A: 11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTN_U_TRPU81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	5 / 10	HIS A 306 ALA A 287 HIS A 300 THR A 299 ALA A 286	None None ACY A 403 (-4.1A) None None	1.19A	1gtnU-5xd7A: undetectable 1gtnV-5xd7A: undetectable	1gtnU-5xd7A: 11.52 1gtnV-5xd7A: 11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIF_A_BEZA349_0 (D-AMINO ACID OXIDASE)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	4 / 5	TYR A 52 TYR A 50 ILE A 110 GLY A 301	None	1.07A	1kifA-5xd7A: undetectable	1kifA-5xd7A: 21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIF_B_BEZB349_0 (D-AMINO ACID OXIDASE)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	4 / 5	TYR A 52 TYR A 50 ILE A 110 GLY A 301	None	1.07A	1kifB-5xd7A: undetectable	1kifB-5xd7A: 21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIF_C_BEZC349_0 (D-AMINO ACID OXIDASE)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	4 / 5	TYR A 52 TYR A 50 ILE A 110 GLY A 301	None	1.08A	1kifC-5xd7A: undetectable	1kifC-5xd7A: 21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIF_D_BEZD349_0 (D-AMINO ACID OXIDASE)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	4 / 5	TYR A 52 TYR A 50 ILE A 110 GLY A 301	None	1.07A	1kifD-5xd7A: undetectable	1kifD-5xd7A: 21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIF_E_BEZE349_0 (D-AMINO ACID OXIDASE)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	4 / 5	TYR A 52 TYR A 50 ILE A 110 GLY A 301	None	1.07A	1kifE-5xd7A: undetectable	1kifE-5xd7A: 21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIF_F_BEZF349_0 (D-AMINO ACID OXIDASE)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	4 / 5	TYR A 52 TYR A 50 ILE A 110 GLY A 301	None	1.07A	1kifF-5xd7A: undetectable	1kifF-5xd7A: 21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIF_G_BEZG349_0 (D-AMINO ACID OXIDASE)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	4 / 5	TYR A 52 TYR A 50 ILE A 110 GLY A 301	None	1.07A	1kifG-5xd7A: undetectable	1kifG-5xd7A: 21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIF_H_BEZH349_0 (D-AMINO ACID OXIDASE)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	4 / 5	TYR A 52 TYR A 50 ILE A 110 GLY A 301	None	1.07A	1kifH-5xd7A: undetectable	1kifH-5xd7A: 21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QVT_A_PRLA311_0 (TRANSCRIPTIONAL REGULATOR QACR)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	4 / 8	GLU A 304 THR A 36 TYR A 50 ILE A 348	None	0.81A	1qvtA-5xd7A: undetectable	1qvtA-5xd7A: 22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QVU_A_PRLA196_0 (TRANSCRIPTIONAL REGULATOR QACR)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	4 / 6	GLU A 351 TRP A 354 THR A 36 TYR A 50	None	1.24A	1qvuA-5xd7A: undetectable	1qvuA-5xd7A: 22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UTD_Q_TRPQ81_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	5 / 10	GLY A 99 HIS A 253 ALA A 104 ILE A 100 SER A 106	None	1.35A	1utdQ-5xd7A: undetectable 1utdR-5xd7A: undetectable	1utdQ-5xd7A: 11.52 1utdR-5xd7A: 11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VE9_A_BEZA352_0 (D-AMINO ACID OXIDASE)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	4 / 5	TYR A 52 TYR A 50 ILE A 110 GLY A 301	None	1.09A	1ve9A-5xd7A: undetectable	1ve9A-5xd7A: 21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DU8_G_BEZG2352_0 (D-AMINO-ACID OXIDASE)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	4 / 5	TYR A 52 TYR A 50 ILE A 110 GLY A 301	None	0.99A	2du8G-5xd7A: undetectable	2du8G-5xd7A: 21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DU8_J_BEZJ3352_0 (D-AMINO-ACID OXIDASE)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	4 / 5	TYR A 52 TYR A 50 ILE A 110 GLY A 301	None	1.11A	2du8J-5xd7A: undetectable	2du8J-5xd7A: 21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OXT_B_SAMB300_1 (NUCLEOSIDE-2'-O-METH YLTRANSFERASE)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	4 / 5	SER A 202 GLY A 171 ASP A 219 ASP A 198	None None None MG A 402 (-2.9A)	1.09A	2oxtB-5xd7A: undetectable	2oxtB-5xd7A: 21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VAV_F_CSCF1383_2 (ACETYL-COA--DEACETYL CEPHALOSPORIN C ACETYLTRANSFERASE)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	3 / 3	LEU A 252 MET A 248 MET A 302	None	0.94A	2vavF-5xd7A: undetectable	2vavF-5xd7A: 20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YZQ_A_SAMA6075_0 (PUTATIVE UNCHARACTERIZED PROTEIN PH1780)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	5 / 12	ILE A 5 ASP A 77 ARG A 119 ILE A 84 GLU A 83	None	1.22A	2yzqA-5xd7A: undetectable	2yzqA-5xd7A: 23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ADX_A_IMNA2_2 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	4 / 7	ILE A 255 ILE A 81 LEU A 289 LEU A 309	None	0.91A	3adxA-5xd7A: undetectable	3adxA-5xd7A: 21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ARR_A_PNXA606_1 (CHITINASE A)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	4 / 7	GLY A 282 LYS A 285 TRP A 90 TYR A 85	None	1.34A	3arrA-5xd7A: 6.7	3arrA-5xd7A: 22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3E23_A_SAMA221_1 (UNCHARACTERIZED PROTEIN RPA2492)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	3 / 3	TYR A 201 ASP A 198 HIS A 29	None MG A 402 (-2.9A) None	0.97A	3e23A-5xd7A: 2.4	3e23A-5xd7A: 20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWX_A_EPAA1_2 (PROTEIN (PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR (PPAR-DELTA)))	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	5 / 12	THR A 38 THR A 37 ILE A 84 MET A 88 LEU A 65	None	1.15A	3gwxA-5xd7A: undetectable	3gwxA-5xd7A: 21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V4T_H_ACTH504_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	3 / 3	LYS A 330 GLU A 351 TRP A 354	None	1.34A	3v4tH-5xd7A: undetectable	3v4tH-5xd7A: 24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VYW_C_SAMC401_1 (MNMC2)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	4 / 6	GLY A 54 ASP A 198 ASN A 251 GLU A 225	None MG A 402 (-2.9A) None None	0.78A	3vywC-5xd7A: undetectable	3vywC-5xd7A: 23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OU1_A_BEZA302_0 (RETRO-ALDOLASE, DESIGN RA114)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	4 / 8	TYR A 50 ILE A 348 ILE A 110 ALA A 274	None	0.99A	4ou1A-5xd7A: 4.6	4ou1A-5xd7A: 21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R38_C_RBFC201_2 (BLUE-LIGHT-ACTIVATED HISTIDINE KINASE 2)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	5 / 9	THR A 37 GLU A 351 LEU A 112 ILE A 280 PHE A 352	None	1.30A	4r38C-5xd7A: undetectable	4r38C-5xd7A: 18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X3M_B_ADNB301_1 (RNA 2'-O RIBOSE METHYLTRANSFERASE)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	5 / 9	LEU A 115 GLY A 47 ILE A 84 MET A 88 LEU A 73	None	1.14A	4x3mB-5xd7A: undetectable	4x3mB-5xd7A: 23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XI3_B_29SB601_1 (ESTROGEN RECEPTOR)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	5 / 12	THR A 3 ALA A 78 ASP A 77 LEU A 112 GLY A 117	None	0.79A	4xi3B-5xd7A: undetectable	4xi3B-5xd7A: 18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEV_P_TRPP101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	5 / 10	HIS A 306 ALA A 287 HIS A 300 THR A 299 ALA A 286	None None ACY A 403 (-4.1A) None None	1.22A	5eevO-5xd7A: undetectable 5eevP-5xd7A: undetectable	5eevO-5xd7A: 11.52 5eevP-5xd7A: 11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEW_P_TRPP101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	5 / 10	HIS A 306 ALA A 287 HIS A 300 THR A 299 ALA A 286	None None ACY A 403 (-4.1A) None None	1.21A	5eewO-5xd7A: undetectable 5eewP-5xd7A: undetectable	5eewO-5xd7A: 11.52 5eewP-5xd7A: 11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEX_P_TRPP101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	5 / 10	HIS A 306 ALA A 287 HIS A 300 THR A 299 ALA A 286	None None ACY A 403 (-4.1A) None None	1.21A	5eexO-5xd7A: undetectable 5eexP-5xd7A: undetectable	5eexO-5xd7A: 11.52 5eexP-5xd7A: 11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEY_P_TRPP101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	5 / 10	HIS A 306 ALA A 287 HIS A 300 THR A 299 ALA A 286	None None ACY A 403 (-4.1A) None None	1.21A	5eeyO-5xd7A: undetectable 5eeyP-5xd7A: undetectable	5eeyO-5xd7A: 11.52 5eeyP-5xd7A: 11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEZ_P_TRPP101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	5 / 10	HIS A 306 ALA A 287 HIS A 300 THR A 299 ALA A 286	None None ACY A 403 (-4.1A) None None	1.21A	5eezO-5xd7A: undetectable 5eezP-5xd7A: undetectable	5eezO-5xd7A: 11.52 5eezP-5xd7A: 11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF0_P_TRPP101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	5 / 10	HIS A 306 ALA A 287 HIS A 300 THR A 299 ALA A 286	None None ACY A 403 (-4.1A) None None	1.21A	5ef0O-5xd7A: undetectable 5ef0P-5xd7A: undetectable	5ef0O-5xd7A: 11.52 5ef0P-5xd7A: 11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF1_P_TRPP101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	5 / 10	HIS A 306 ALA A 287 HIS A 300 THR A 299 ALA A 286	None None ACY A 403 (-4.1A) None None	1.21A	5ef1O-5xd7A: undetectable 5ef1P-5xd7A: undetectable	5ef1O-5xd7A: 11.52 5ef1P-5xd7A: 11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF2_P_TRPP101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	5 / 10	HIS A 306 ALA A 287 HIS A 300 THR A 299 ALA A 286	None None ACY A 403 (-4.1A) None None	1.21A	5ef2O-5xd7A: undetectable 5ef2P-5xd7A: undetectable	5ef2O-5xd7A: 11.52 5ef2P-5xd7A: 11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF3_P_TRPP101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	5 / 10	HIS A 306 ALA A 287 HIS A 300 THR A 299 ALA A 286	None None ACY A 403 (-4.1A) None None	1.21A	5ef3O-5xd7A: undetectable 5ef3P-5xd7A: undetectable	5ef3O-5xd7A: 11.52 5ef3P-5xd7A: 11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IL1_A_SAMA601_0 (METTL3)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	5 / 12	ILE A 170 ARG A 172 LEU A 144 SER A 322 GLU A 224	None None None None MG A 402 (-3.3A)	1.31A	5il1A-5xd7A: undetectable	5il1A-5xd7A: 20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6G9B_B_IXXB705_1 (ENVELOPE GLYCOPROTEIN,ENVELOP E GLYCOPROTEIN ENVELOPE GLYCOPROTEIN)	5xd7	3,6-ANHYDRO-ALPHA-L- GALACTONATE CYCLOISOMERASE (Vibrio sp. EJY3)	4 / 5	ALA A 184 TYR A 218 GLN A 176 ILE A 179	None	1.20A	6g9bA-5xd7A: undetectable 6g9bB-5xd7A: undetectable	6g9bA-5xd7A: 12.50 6g9bB-5xd7A: 12.42

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1BX4_A_ADNA350_2","PROTEIN (ADENOSINE KINASE)","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",3,"LEU A 318;SER A 308;ASN A 133","None","0.69A","1bx4A-5xd7A:undetectable","1bx4A-5xd7A:22.09"],["1GTN_O_TRPO81_0","TRP RNA-BINDING ATTENUATION PROTEIN","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",5,"HIS A 306;ALA A 287;HIS A 300;THR A 299;ALA A 286","None;None;ACY A 403 (-4.1A);None;None","1.17A","1gtnO-5xd7A:undetectable;1gtnP-5xd7A:undetectable","1gtnO-5xd7A:11.52;1gtnP-5xd7A:11.52"],["1GTN_U_TRPU81_0","TRP RNA-BINDING ATTENUATION PROTEIN","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",5,"HIS A 306;ALA A 287;HIS A 300;THR A 299;ALA A 286","None;None;ACY A 403 (-4.1A);None;None","1.19A","1gtnU-5xd7A:undetectable;1gtnV-5xd7A:undetectable","1gtnU-5xd7A:11.52;1gtnV-5xd7A:11.52"],["1KIF_A_BEZA349_0","D-AMINO ACID OXIDASE","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",4,"TYR A  52;TYR A  50;ILE A 110;GLY A 301","None","1.07A","1kifA-5xd7A:undetectable","1kifA-5xd7A:21.66"],["1KIF_B_BEZB349_0","D-AMINO ACID OXIDASE","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",4,"TYR A  52;TYR A  50;ILE A 110;GLY A 301","None","1.07A","1kifB-5xd7A:undetectable","1kifB-5xd7A:21.66"],["1KIF_C_BEZC349_0","D-AMINO ACID OXIDASE","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",4,"TYR A  52;TYR A  50;ILE A 110;GLY A 301","None","1.08A","1kifC-5xd7A:undetectable","1kifC-5xd7A:21.66"],["1KIF_D_BEZD349_0","D-AMINO ACID OXIDASE","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",4,"TYR A  52;TYR A  50;ILE A 110;GLY A 301","None","1.07A","1kifD-5xd7A:undetectable","1kifD-5xd7A:21.66"],["1KIF_E_BEZE349_0","D-AMINO ACID OXIDASE","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",4,"TYR A  52;TYR A  50;ILE A 110;GLY A 301","None","1.07A","1kifE-5xd7A:undetectable","1kifE-5xd7A:21.66"],["1KIF_F_BEZF349_0","D-AMINO ACID OXIDASE","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",4,"TYR A  52;TYR A  50;ILE A 110;GLY A 301","None","1.07A","1kifF-5xd7A:undetectable","1kifF-5xd7A:21.66"],["1KIF_G_BEZG349_0","D-AMINO ACID OXIDASE","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",4,"TYR A  52;TYR A  50;ILE A 110;GLY A 301","None","1.07A","1kifG-5xd7A:undetectable","1kifG-5xd7A:21.66"],["1KIF_H_BEZH349_0","D-AMINO ACID OXIDASE","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",4,"TYR A  52;TYR A  50;ILE A 110;GLY A 301","None","1.07A","1kifH-5xd7A:undetectable","1kifH-5xd7A:21.66"],["1QVT_A_PRLA311_0","TRANSCRIPTIONAL REGULATOR QACR","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",4,"GLU A 304;THR A  36;TYR A  50;ILE A 348","None","0.81A","1qvtA-5xd7A:undetectable","1qvtA-5xd7A:22.01"],["1QVU_A_PRLA196_0","TRANSCRIPTIONAL REGULATOR QACR","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",4,"GLU A 351;TRP A 354;THR A  36;TYR A  50","None","1.24A","1qvuA-5xd7A:undetectable","1qvuA-5xd7A:22.01"],["1UTD_Q_TRPQ81_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",5,"GLY A  99;HIS A 253;ALA A 104;ILE A 100;SER A 106","None","1.35A","1utdQ-5xd7A:undetectable;1utdR-5xd7A:undetectable","1utdQ-5xd7A:11.52;1utdR-5xd7A:11.52"],["1VE9_A_BEZA352_0","D-AMINO ACID OXIDASE","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",4,"TYR A  52;TYR A  50;ILE A 110;GLY A 301","None","1.09A","1ve9A-5xd7A:undetectable","1ve9A-5xd7A:21.66"],["2DU8_G_BEZG2352_0","D-AMINO-ACID OXIDASE","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",4,"TYR A  52;TYR A  50;ILE A 110;GLY A 301","None","0.99A","2du8G-5xd7A:undetectable","2du8G-5xd7A:21.88"],["2DU8_J_BEZJ3352_0","D-AMINO-ACID OXIDASE","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",4,"TYR A  52;TYR A  50;ILE A 110;GLY A 301","None","1.11A","2du8J-5xd7A:undetectable","2du8J-5xd7A:21.88"],["2OXT_B_SAMB300_1","NUCLEOSIDE-2'-O-METHYLTRANSFERASE","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",4,"SER A 202;GLY A 171;ASP A 219;ASP A 198","None;None;None; MG A 402 (-2.9A)","1.09A","2oxtB-5xd7A:undetectable","2oxtB-5xd7A:21.32"],["2VAV_F_CSCF1383_2","ACETYL-COA--DEACETYLCEPHALOSPORIN C ACETYLTRANSFERASE","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",3,"LEU A 252;MET A 248;MET A 302","None","0.94A","2vavF-5xd7A:undetectable","2vavF-5xd7A:20.58"],["2YZQ_A_SAMA6075_0","PUTATIVE UNCHARACTERIZED PROTEIN PH1780","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",5,"ILE A   5;ASP A  77;ARG A 119;ILE A  84;GLU A  83","None","1.22A","2yzqA-5xd7A:undetectable","2yzqA-5xd7A:23.81"],["3ADX_A_IMNA2_2","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",4,"ILE A 255;ILE A  81;LEU A 289;LEU A 309","None","0.91A","3adxA-5xd7A:undetectable","3adxA-5xd7A:21.01"],["3ARR_A_PNXA606_1","CHITINASE A","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",4,"GLY A 282;LYS A 285;TRP A  90;TYR A  85","None","1.34A","3arrA-5xd7A:6.7","3arrA-5xd7A:22.09"],["3E23_A_SAMA221_1","UNCHARACTERIZED PROTEIN RPA2492","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",3,"TYR A 201;ASP A 198;HIS A  29","None; MG A 402 (-2.9A);None","0.97A","3e23A-5xd7A:2.4","3e23A-5xd7A:20.97"],["3GWX_A_EPAA1_2","PROTEIN (PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR (PPAR-DELTA))","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",5,"THR A  38;THR A  37;ILE A  84;MET A  88;LEU A  65","None","1.15A","3gwxA-5xd7A:undetectable","3gwxA-5xd7A:21.90"],["3V4T_H_ACTH504_0","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",3,"LYS A 330;GLU A 351;TRP A 354","None","1.34A","3v4tH-5xd7A:undetectable","3v4tH-5xd7A:24.67"],["3VYW_C_SAMC401_1","MNMC2","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",4,"GLY A  54;ASP A 198;ASN A 251;GLU A 225","None; MG A 402 (-2.9A);None;None","0.78A","3vywC-5xd7A:undetectable","3vywC-5xd7A:23.26"],["4OU1_A_BEZA302_0","RETRO-ALDOLASE, DESIGN RA114","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",4,"TYR A  50;ILE A 348;ILE A 110;ALA A 274","None","0.99A","4ou1A-5xd7A:4.6","4ou1A-5xd7A:21.77"],["4R38_C_RBFC201_2","BLUE-LIGHT-ACTIVATED HISTIDINE KINASE 2","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",5,"THR A  37;GLU A 351;LEU A 112;ILE A 280;PHE A 352","None","1.30A","4r38C-5xd7A:undetectable","4r38C-5xd7A:18.70"],["4X3M_B_ADNB301_1","RNA 2'-O RIBOSE METHYLTRANSFERASE","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",5,"LEU A 115;GLY A  47;ILE A  84;MET A  88;LEU A  73","None","1.14A","4x3mB-5xd7A:undetectable","4x3mB-5xd7A:23.14"],["4XI3_B_29SB601_1","ESTROGEN RECEPTOR","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",5,"THR A   3;ALA A  78;ASP A  77;LEU A 112;GLY A 117","None","0.79A","4xi3B-5xd7A:undetectable","4xi3B-5xd7A:18.43"],["5EEV_P_TRPP101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",5,"HIS A 306;ALA A 287;HIS A 300;THR A 299;ALA A 286","None;None;ACY A 403 (-4.1A);None;None","1.22A","5eevO-5xd7A:undetectable;5eevP-5xd7A:undetectable","5eevO-5xd7A:11.52;5eevP-5xd7A:11.52"],["5EEW_P_TRPP101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",5,"HIS A 306;ALA A 287;HIS A 300;THR A 299;ALA A 286","None;None;ACY A 403 (-4.1A);None;None","1.21A","5eewO-5xd7A:undetectable;5eewP-5xd7A:undetectable","5eewO-5xd7A:11.52;5eewP-5xd7A:11.52"],["5EEX_P_TRPP101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",5,"HIS A 306;ALA A 287;HIS A 300;THR A 299;ALA A 286","None;None;ACY A 403 (-4.1A);None;None","1.21A","5eexO-5xd7A:undetectable;5eexP-5xd7A:undetectable","5eexO-5xd7A:11.52;5eexP-5xd7A:11.52"],["5EEY_P_TRPP101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",5,"HIS A 306;ALA A 287;HIS A 300;THR A 299;ALA A 286","None;None;ACY A 403 (-4.1A);None;None","1.21A","5eeyO-5xd7A:undetectable;5eeyP-5xd7A:undetectable","5eeyO-5xd7A:11.52;5eeyP-5xd7A:11.52"],["5EEZ_P_TRPP101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",5,"HIS A 306;ALA A 287;HIS A 300;THR A 299;ALA A 286","None;None;ACY A 403 (-4.1A);None;None","1.21A","5eezO-5xd7A:undetectable;5eezP-5xd7A:undetectable","5eezO-5xd7A:11.52;5eezP-5xd7A:11.52"],["5EF0_P_TRPP101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",5,"HIS A 306;ALA A 287;HIS A 300;THR A 299;ALA A 286","None;None;ACY A 403 (-4.1A);None;None","1.21A","5ef0O-5xd7A:undetectable;5ef0P-5xd7A:undetectable","5ef0O-5xd7A:11.52;5ef0P-5xd7A:11.52"],["5EF1_P_TRPP101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",5,"HIS A 306;ALA A 287;HIS A 300;THR A 299;ALA A 286","None;None;ACY A 403 (-4.1A);None;None","1.21A","5ef1O-5xd7A:undetectable;5ef1P-5xd7A:undetectable","5ef1O-5xd7A:11.52;5ef1P-5xd7A:11.52"],["5EF2_P_TRPP101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",5,"HIS A 306;ALA A 287;HIS A 300;THR A 299;ALA A 286","None;None;ACY A 403 (-4.1A);None;None","1.21A","5ef2O-5xd7A:undetectable;5ef2P-5xd7A:undetectable","5ef2O-5xd7A:11.52;5ef2P-5xd7A:11.52"],["5EF3_P_TRPP101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",5,"HIS A 306;ALA A 287;HIS A 300;THR A 299;ALA A 286","None;None;ACY A 403 (-4.1A);None;None","1.21A","5ef3O-5xd7A:undetectable;5ef3P-5xd7A:undetectable","5ef3O-5xd7A:11.52;5ef3P-5xd7A:11.52"],["5IL1_A_SAMA601_0","METTL3","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",5,"ILE A 170;ARG A 172;LEU A 144;SER A 322;GLU A 224","None;None;None;None; MG A 402 (-3.3A)","1.31A","5il1A-5xd7A:undetectable","5il1A-5xd7A:20.55"],["6G9B_B_IXXB705_1","ENVELOPE GLYCOPROTEIN,ENVELOPE GLYCOPROTEIN;ENVELOPE GLYCOPROTEIN","5xd7","3,6-ANHYDRO-ALPHA-L-GALACTONATE CYCLOISOMERASE","Vibrio sp. EJY3",4,"ALA A 184;TYR A 218;GLN A 176;ILE A 179","None","1.20A","6g9bA-5xd7A:undetectable;6g9bB-5xd7A:undetectable","6g9bA-5xd7A:12.50;6g9bB-5xd7A:12.42"]]