SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xe0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA502_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 6 ASN A 297
ASN A 298
ILE A 320
GLY A 203
 None
 0.98A 1oniA-5xe0A:
undetectable
1oniB-5xe0A:
undetectable		 1oniA-5xe0A:
14.92
1oniB-5xe0A:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 6 ASN A 297
ASN A 298
ILE A 320
GLY A 203
 None
 1.00A 1oniD-5xe0A:
undetectable
1oniF-5xe0A:
undetectable		 1oniD-5xe0A:
14.92
1oniF-5xe0A:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 8 HIS A 419
PRO A 386
PHE A 457
ASP A 211
 None
 1.12A 1p7lC-5xe0A:
undetectable		 1p7lC-5xe0A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 8 HIS A 419
PRO A 386
PHE A 457
ASP A 211
 None
 1.12A 1p7lD-5xe0A:
undetectable		 1p7lD-5xe0A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7R_A_NCTA440_1
(CYTOCHROME P450-CAM)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 7 PHE A  30
VAL A 435
VAL A 410
ILE A 397
 None
 1.00A 1p7rA-5xe0A:
undetectable		 1p7rA-5xe0A:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 8 HIS A 419
PRO A 386
PHE A 457
ASP A 211
 None
 1.14A 1rg9A-5xe0A:
undetectable		 1rg9A-5xe0A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 8 HIS A 419
PRO A 386
PHE A 457
ASP A 211
 None
 1.14A 1rg9B-5xe0A:
undetectable		 1rg9B-5xe0A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 8 HIS A 419
PRO A 386
PHE A 457
ASP A 211
 None
 1.12A 1rg9C-5xe0A:
undetectable		 1rg9C-5xe0A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 8 HIS A 419
PRO A 386
PHE A 457
ASP A 211
 None
 1.13A 1rg9D-5xe0A:
undetectable		 1rg9D-5xe0A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 7 TYR A 322
ASP A 324
ASP A 325
LYS A 355
 None
GTP  A 501 ( 4.2A)
None
GTP  A 501 (-3.5A)
 0.91A 1t03A-5xe0A:
4.2		 1t03A-5xe0A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TBF_A_VIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		5 / 9 LEU A 305
LEU A 339
VAL A 326
LEU A 221
PHE A 226
 None
 1.27A 1tbfA-5xe0A:
undetectable		 1tbfA-5xe0A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 8 ILE A 291
PHE A 194
TYR A  77
LEU A 249
 None
 0.92A 2eikN-5xe0A:
undetectable
2eikW-5xe0A:
undetectable		 2eikN-5xe0A:
20.98
2eikW-5xe0A:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 8 ILE A 291
PHE A 194
TYR A  77
LEU A 249
 None
 0.91A 2eilN-5xe0A:
undetectable
2eilW-5xe0A:
undetectable		 2eilN-5xe0A:
20.98
2eilW-5xe0A:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 6 ILE A  86
TYR A  77
MET A 295
THR A 294
 None
 0.95A 2einN-5xe0A:
undetectable
2einW-5xe0A:
undetectable		 2einN-5xe0A:
20.98
2einW-5xe0A:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 8 HIS A 419
PRO A 386
PHE A 457
ASP A 211
 None
 1.23A 2p02A-5xe0A:
undetectable		 2p02A-5xe0A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 5 ILE A  86
TYR A  77
MET A 295
THR A 294
 None
 0.90A 3abkN-5xe0A:
undetectable
3abkW-5xe0A:
undetectable		 3abkN-5xe0A:
20.98
3abkW-5xe0A:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 5 ILE A 126
TYR A  98
ARG A 129
MET A  97
 None
 1.31A 3abkN-5xe0A:
undetectable
3abkW-5xe0A:
undetectable		 3abkN-5xe0A:
20.98
3abkW-5xe0A:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 8 ILE A 291
PHE A 194
TYR A  77
LEU A 249
 None
 0.91A 3ablN-5xe0A:
undetectable
3ablW-5xe0A:
undetectable		 3ablN-5xe0A:
20.98
3ablW-5xe0A:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 7 ILE A  86
TYR A  77
MET A 295
THR A 294
 None
 0.85A 3ag2N-5xe0A:
undetectable
3ag2W-5xe0A:
undetectable		 3ag2N-5xe0A:
20.98
3ag2W-5xe0A:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I45_A_NIOA500_1
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 8 LEU A 252
TYR A 254
PHE A 187
LEU A 190
 None
 0.94A 3i45A-5xe0A:
undetectable		 3i45A-5xe0A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		5 / 10 SER A 180
LEU A 190
ILE A 291
SER A 286
GLY A 288
 None
 1.42A 3iluB-5xe0A:
undetectable
3iluE-5xe0A:
undetectable		 3iluB-5xe0A:
21.18
3iluE-5xe0A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_A_GJZA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 6 LEU A 370
PHE A 369
ILE A 320
ALA A 321
 None
 0.79A 3mdrA-5xe0A:
undetectable		 3mdrA-5xe0A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5P_A_TACA7101_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		5 / 12 VAL A 308
ILE A 300
PHE A 317
ILE A 334
TYR A 330
 None
 1.22A 3q5pA-5xe0A:
undetectable		 3q5pA-5xe0A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_1
(PROTEASE)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		5 / 9 ILE A 301
VAL A 326
GLY A 323
ILE A 299
ILE A 300
 None
 0.97A 3s43A-5xe0A:
undetectable		 3s43A-5xe0A:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		6 / 9 ASP A 234
ASN A 293
TYR A 322
GLY A 323
ASP A 324
ASP A 325
 GTP  A 501 (-2.6A)
None
None
None
GTP  A 501 ( 4.2A)
None
 0.64A 3sfuA-5xe0A:
31.4		 3sfuA-5xe0A:
27.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		5 / 9 SER A 284
ASN A 293
TYR A 322
ASP A 324
ASP A 325
 GTP  A 501 (-4.0A)
None
None
GTP  A 501 ( 4.2A)
None
 1.06A 3sfuA-5xe0A:
31.4		 3sfuA-5xe0A:
27.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		5 / 9 SER A 284
THR A 289
TYR A 322
ASP A 324
ASP A 325
 GTP  A 501 (-4.0A)
None
None
GTP  A 501 ( 4.2A)
None
 1.06A 3sfuA-5xe0A:
31.4		 3sfuA-5xe0A:
27.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		5 / 9 THR A 289
TYR A 322
GLY A 323
ASP A 324
ASP A 325
 None
None
None
GTP  A 501 ( 4.2A)
None
 0.61A 3sfuA-5xe0A:
31.4		 3sfuA-5xe0A:
27.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_B_RBVB601_1
(RNA POLYMERASE)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		7 / 9 ASP A 234
ASN A 293
TYR A 322
GLY A 323
ASP A 324
ASP A 325
LEU A 370
 GTP  A 501 (-2.6A)
None
None
None
GTP  A 501 ( 4.2A)
None
None
 0.63A 3sfuB-5xe0A:
31.3		 3sfuB-5xe0A:
27.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		6 / 11 LYS A 155
ARG A 170
ASP A 234
ASN A 293
GLY A 323
ASP A 324
 GTP  A 501 (-4.8A)
GTP  A 501 (-3.7A)
GTP  A 501 (-2.6A)
None
None
GTP  A 501 ( 4.2A)
 0.87A 3sfuC-5xe0A:
31.4		 3sfuC-5xe0A:
27.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		5 / 11 LYS A 155
ASP A 234
THR A 289
GLY A 323
ASP A 324
 GTP  A 501 (-4.8A)
GTP  A 501 (-2.6A)
None
None
GTP  A 501 ( 4.2A)
 0.87A 3sfuC-5xe0A:
31.4		 3sfuC-5xe0A:
27.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 6 ILE A  86
TYR A  77
MET A 295
THR A 294
 None
 0.84A 3wg7A-5xe0A:
undetectable
3wg7J-5xe0A:
undetectable		 3wg7A-5xe0A:
20.98
3wg7J-5xe0A:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 6 ILE A  86
TYR A  77
MET A 295
THR A 294
 None
 0.85A 3wg7N-5xe0A:
undetectable
3wg7W-5xe0A:
undetectable		 3wg7N-5xe0A:
20.98
3wg7W-5xe0A:
8.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K50_B_ACTB701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		3 / 3 HIS A 195
GLY A 288
ILE A 291
 None
 0.33A 4k50A-5xe0A:
51.9		 4k50A-5xe0A:
55.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K50_J_ACTJ701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		3 / 3 HIS A 195
GLY A 288
ILE A 291
 None
 0.32A 4k50I-5xe0A:
51.9		 4k50I-5xe0A:
55.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 7 HIS A 419
PRO A 386
PHE A 457
ASP A 211
 None
 1.25A 4ndnC-5xe0A:
undetectable		 4ndnC-5xe0A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODJ_A_SAMA500_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 7 HIS A 419
PRO A 386
PHE A 457
ASP A 211
 None
 1.21A 4odjA-5xe0A:
undetectable		 4odjA-5xe0A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 8 GLY A 281
TYR A 263
SER A 267
SER A 286
 None
 1.03A 4ws1A-5xe0A:
undetectable		 4ws1A-5xe0A:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_A_SAMA1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		5 / 12 GLY A 232
TYR A 230
GLU A 173
ALA A 235
TYR A  58
 GTP  A 501 (-3.6A)
None
None
None
None
 1.27A 4ymgA-5xe0A:
undetectable		 4ymgA-5xe0A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 8 HIS A 419
PRO A 386
PHE A 457
ASP A 211
 None
 1.19A 5a1iA-5xe0A:
undetectable		 5a1iA-5xe0A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 7 HIS A 419
PRO A 386
PHE A 457
ASP A 211
 None
 1.19A 5a1iA-5xe0A:
undetectable		 5a1iA-5xe0A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 7 ILE A  86
TYR A  77
MET A 295
THR A 294
 None
 0.87A 5b1bN-5xe0A:
undetectable
5b1bW-5xe0A:
undetectable		 5b1bN-5xe0A:
20.98
5b1bW-5xe0A:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 7 ILE A  86
TYR A  77
MET A 295
THR A 294
 None
 0.86A 5b3sN-5xe0A:
undetectable
5b3sW-5xe0A:
undetectable		 5b3sN-5xe0A:
20.98
5b3sW-5xe0A:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZY_A_SAMA603_0
(LEGIONELLA EFFECTOR
LEGAS4)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		5 / 12 LEU A 103
GLY A 102
SER A  87
PHE A 187
TYR A 254
 None
 1.17A 5czyA-5xe0A:
undetectable		 5czyA-5xe0A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 8 HIS A 419
GLY A 421
VAL A 387
HIS A 385
 None
 0.80A 5f8yA-5xe0A:
undetectable		 5f8yA-5xe0A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 8 HIS A 419
PRO A 386
PHE A 457
ASP A 211
 None
 1.16A 5t8sB-5xe0A:
undetectable		 5t8sB-5xe0A:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 6 ILE A  86
TYR A  77
MET A 295
THR A 294
 None
 0.89A 5z86N-5xe0A:
undetectable
5z86W-5xe0A:
undetectable		 5z86N-5xe0A:
20.98
5z86W-5xe0A:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 6 ILE A  86
TYR A  77
MET A 295
THR A 294
 None
 0.92A 5zcoN-5xe0A:
undetectable
5zcoW-5xe0A:
undetectable		 5zcoN-5xe0A:
20.98
5zcoW-5xe0A:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 8 ILE A 291
PHE A 194
TYR A  77
LEU A 249
 None
 0.94A 5zcqN-5xe0A:
undetectable
5zcqW-5xe0A:
undetectable		 5zcqN-5xe0A:
20.98
5zcqW-5xe0A:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 8 HIS A 419
PRO A 386
PHE A 457
ASP A 211
 None
 1.21A 6fboA-5xe0A:
undetectable		 6fboA-5xe0A:
10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 8 HIS A 419
PRO A 386
PHE A 457
ASP A 211
 None
 1.19A 6fcdA-5xe0A:
undetectable		 6fcdA-5xe0A:
10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G6R_A_SAMA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 7 HIS A 419
PRO A 386
PHE A 457
ASP A 211
 None
 1.19A 6g6rA-5xe0A:
undetectable		 6g6rA-5xe0A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		5 / 12 ILE A 296
TYR A  77
ILE A  86
PHE A 187
MET A 183
 None
 1.40A 6j20A-5xe0A:
undetectable		 6j20A-5xe0A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JI6_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME)		 5xe0 GENOME POLYPROTEIN
(Enterovirus
D) 		4 / 5 GLY A 145
LEU A 141
SER A 176
TYR A 116
 None
 1.14A 6ji6A-5xe0A:
undetectable		 6ji6A-5xe0A:
18.80