SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xe3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_1
(ESTROGEN RECEPTOR)		 5xe3 ENDORIBONUCLEASE
MAZF4
(Mycobacterium
tuberculosis) 		4 / 6 ALA C  66
ASP C  67
ARG C   6
MET C  54
 None
 1.27A 2ouzA-5xe3C:
undetectable		 2ouzA-5xe3C:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_D_486D2_2
(GLUCOCORTICOID
RECEPTOR)		 5xe3 ENDORIBONUCLEASE
MAZF4
(Mycobacterium
tuberculosis) 		4 / 5 LEU C   5
ASN C  30
MET C  89
TYR C  10
 None
 1.44A 3h52D-5xe3C:
undetectable		 3h52D-5xe3C:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_A_OBNA1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5xe3 ENDORIBONUCLEASE
MAZF4
(Mycobacterium
tuberculosis) 		5 / 11 PRO C  56
ASP C  58
VAL C  64
THR C  88
ILE C  92
 None
 1.33A 3n23A-5xe3C:
undetectable		 3n23A-5xe3C:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HYR_B_ESTB601_1
(ESTROGEN RECEPTOR)		 5xe3 ENDORIBONUCLEASE
MAZF4
PROBABLE ANTITOXIN
MAZE4
(Mycobacterium
tuberculosis) 		5 / 11 LEU C  96
ALA C  99
LEU C 102
HIS F 158
LEU F 162
 None
 1.47A 5hyrB-5xe3C:
undetectable		 5hyrB-5xe3C:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_B_TRPB403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)		 5xe3 ENDORIBONUCLEASE
MAZF4
(Mycobacterium
tuberculosis) 		4 / 7 ARG C   6
GLU C  83
THR C  88
PRO C  59
 None
 1.08A 6a4iB-5xe3C:
undetectable		 6a4iB-5xe3C:
13.61