SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xeb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_A_CCSA417_0
(ESTROGEN RECEPTOR)		 5xeb ENVELOPE
GLYCOPROTEIN
(Dhori
thogotovirus) 		3 / 3 GLU A 288
LYS A  54
VAL A  53
 None
 0.78A 1l2iA-5xebA:
undetectable		 1l2iA-5xebA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP3_B_AICB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5xeb ENVELOPE
GLYCOPROTEIN
(Dhori
thogotovirus) 		3 / 3 ALA A 185
ARG A 173
LYS A 305
 None
 1.04A 3kp3B-5xebA:
undetectable		 3kp3B-5xebA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOR_A_FLPA711_1
(LACTOTRANSFERRIN)		 5xeb ENVELOPE
GLYCOPROTEIN
(Dhori
thogotovirus) 		4 / 7 GLY A 190
VAL A 186
PRO A 188
ASN A 189
 None
None
None
NAG  A 601 (-1.9A)
 0.86A 4forA-5xebA:
undetectable		 4forA-5xebA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_A_ECNA403_1
(FLAVOHEMOGLOBIN)		 5xeb ENVELOPE
GLYCOPROTEIN
(Dhori
thogotovirus) 		5 / 12 TYR A  68
ALA A 460
LEU A 461
THR A 464
LEU A  92
 None
 1.12A 4g1bA-5xebA:
undetectable		 4g1bA-5xebA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 5xeb ENVELOPE
GLYCOPROTEIN
(Dhori
thogotovirus) 		3 / 3 SER A 160
TYR A 146
PRO A 115
 None
 0.98A 4k8cA-5xebA:
undetectable		 4k8cA-5xebA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5xeb ENVELOPE
GLYCOPROTEIN
(Dhori
thogotovirus) 		3 / 3 SER A 160
TYR A 146
PRO A 115
 None
 0.96A 4kahA-5xebA:
undetectable		 4kahA-5xebA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5xeb ENVELOPE
GLYCOPROTEIN
(Dhori
thogotovirus) 		3 / 3 SER A 160
TYR A 146
PRO A 115
 None
 0.97A 4kahB-5xebA:
undetectable		 4kahB-5xebA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5xeb ENVELOPE
GLYCOPROTEIN
(Dhori
thogotovirus) 		3 / 3 SER A 160
TYR A 146
PRO A 115
 None
 0.97A 4kanA-5xebA:
undetectable		 4kanA-5xebA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5xeb ENVELOPE
GLYCOPROTEIN
(Dhori
thogotovirus) 		3 / 3 SER A 160
TYR A 146
PRO A 115
 None
 0.98A 4kanB-5xebA:
undetectable		 4kanB-5xebA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5xeb ENVELOPE
GLYCOPROTEIN
(Dhori
thogotovirus) 		3 / 3 SER A 160
TYR A 146
PRO A 115
 None
 0.97A 4kbeA-5xebA:
undetectable		 4kbeA-5xebA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5xeb ENVELOPE
GLYCOPROTEIN
(Dhori
thogotovirus) 		3 / 3 SER A 160
TYR A 146
PRO A 115
 None
 0.97A 4lbgA-5xebA:
undetectable		 4lbgA-5xebA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5xeb ENVELOPE
GLYCOPROTEIN
(Dhori
thogotovirus) 		3 / 3 SER A 160
TYR A 146
PRO A 115
 None
 0.96A 4lbgB-5xebA:
undetectable		 4lbgB-5xebA:
23.42