SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xg8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5xg8 GALACTOSIDE-BINDING
SOLUBLE LECTIN 13
(Homo
sapiens) 		4 / 8 ILE A  93
GLY A 111
MET A  64
ILE A 109
 None
 0.93A 2qwxA-5xg8A:
undetectable
2qwxB-5xg8A:
undetectable		 2qwxA-5xg8A:
16.59
2qwxB-5xg8A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IW1_A_ASDA1223_1
(CYTOCHROME P450
CYP125)		 5xg8 GALACTOSIDE-BINDING
SOLUBLE LECTIN 13
(Homo
sapiens) 		5 / 12 ILE A 102
VAL A  95
VAL A  20
VAL A 124
VAL A  38
 None
 1.09A 3iw1A-5xg8A:
undetectable		 3iw1A-5xg8A:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB806_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5xg8 GALACTOSIDE-BINDING
SOLUBLE LECTIN 13
(Homo
sapiens) 		4 / 7 SER A  29
PHE A  30
ASN A  32
ASP A  33
 None
 1.32A 4kcnB-5xg8A:
undetectable		 4kcnB-5xg8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_MTLA805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5xg8 GALACTOSIDE-BINDING
SOLUBLE LECTIN 13
(Homo
sapiens) 		4 / 8 SER A  29
PHE A  30
ASN A  32
ASP A  33
 None
 1.32A 5vunA-5xg8A:
undetectable		 5vunA-5xg8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5xg8 GALACTOSIDE-BINDING
SOLUBLE LECTIN 13
(Homo
sapiens) 		4 / 8 SER A  29
PHE A  30
ASN A  32
ASP A  33
 None
 1.32A 5vunB-5xg8A:
undetectable		 5vunB-5xg8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5xg8 GALACTOSIDE-BINDING
SOLUBLE LECTIN 13
(Homo
sapiens) 		4 / 8 SER A  29
PHE A  30
ASN A  32
ASP A  33
 None
 1.34A 5vuoB-5xg8A:
undetectable		 5vuoB-5xg8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5xg8 GALACTOSIDE-BINDING
SOLUBLE LECTIN 13
(Homo
sapiens) 		4 / 8 SER A  29
PHE A  30
ASN A  32
ASP A  33
 None
 1.29A 6auuB-5xg8A:
undetectable		 6auuB-5xg8A:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B8K_A_W9TA300_0
(GALECTIN-3)		 5xg8 GALACTOSIDE-BINDING
SOLUBLE LECTIN 13
(Homo
sapiens) 		4 / 7 HIS A  53
ASN A  65
TRP A  72
GLU A  75
 GOL  A 201 (-3.5A)
GOL  A 201 (-3.7A)
GOL  A 201 (-3.0A)
GOL  A 201 (-2.8A)
 0.67A 6b8kA-5xg8A:
22.4		 6b8kA-5xg8A:
32.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		 5xg8 GALACTOSIDE-BINDING
SOLUBLE LECTIN 13
(Homo
sapiens) 		4 / 8 HIS A  53
HIS A  57
ASN A  65
GLU A  75
 GOL  A 201 (-3.5A)
None
GOL  A 201 (-3.7A)
GOL  A 201 (-2.8A)
 1.07A 6b94A-5xg8A:
17.9		 6b94A-5xg8A:
23.86