SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xge'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_0
(ALCOHOL
DEHYDROGENASE)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
3 / 3 MET A 367
LEU A 370
SER A 371
None
0.69A 1ee2A-5xgeA:
undetectable
1ee2A-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 10 GLY A 755
HIS A 756
HIS A 753
THR A 762
ILE A 751
None
1.43A 1gtfT-5xgeA:
undetectable
1gtfU-5xgeA:
undetectable
1gtfT-5xgeA:
undetectable
1gtfU-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 11 GLY A 755
HIS A 756
HIS A 753
THR A 762
GLY A 780
None
1.14A 1gtnT-5xgeA:
undetectable
1gtnU-5xgeA:
undetectable
1gtnT-5xgeA:
undetectable
1gtnU-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1501_0
(FERROCHELATASE)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 12 LEU A 339
LEU A 357
ILE A 312
LEU A 270
VAL A 353
None
1.22A 1hrkA-5xgeA:
undetectable
1hrkA-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_B_117B1_1
(HMG-COA REDUCTASE)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 11 ASN A 402
SER A 508
LEU A 396
ALA A 513
LEU A 510
None
1.22A 1hwkA-5xgeA:
2.9
1hwkA-5xgeA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_B_BEZB201_0
(PEROXIREDOXIN 5)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 9 GLY A 702
CYH A 703
LEU A 628
PHE A 625
THR A 674
None
1.38A 1oc3B-5xgeA:
undetectable
1oc3B-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 10 GLY A 755
HIS A 756
HIS A 753
THR A 762
ILE A 751
None
1.43A 1utdN-5xgeA:
undetectable
1utdO-5xgeA:
undetectable
1utdN-5xgeA:
undetectable
1utdO-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 11 GLY A 780
GLY A 755
HIS A 756
HIS A 753
THR A 762
None
1.14A 1utdL-5xgeA:
undetectable
1utdV-5xgeA:
undetectable
1utdL-5xgeA:
undetectable
1utdV-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
4 / 8 LYS A 699
PHE A 665
LEU A 661
PHE A 657
None
0.85A 1v54C-5xgeA:
undetectable
1v54J-5xgeA:
undetectable
1v54C-5xgeA:
undetectable
1v54J-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
4 / 8 LYS A 699
PHE A 665
LEU A 661
PHE A 657
None
0.77A 1v54P-5xgeA:
undetectable
1v54W-5xgeA:
undetectable
1v54P-5xgeA:
undetectable
1v54W-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 12 LEU A 443
LEU A 476
GLY A 458
ARG A 391
ALA A 450
None
1.09A 2bm9D-5xgeA:
undetectable
2bm9D-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
4 / 8 LYS A 699
PHE A 665
LEU A 661
PHE A 657
None
0.82A 2dyrP-5xgeA:
undetectable
2dyrW-5xgeA:
undetectable
2dyrP-5xgeA:
undetectable
2dyrW-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
4 / 8 LYS A 699
PHE A 665
LEU A 661
PHE A 657
None
0.76A 2eikP-5xgeA:
undetectable
2eikW-5xgeA:
undetectable
2eikP-5xgeA:
undetectable
2eikW-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
4 / 8 LYS A 699
PHE A 665
LEU A 661
PHE A 657
None
0.81A 2eilC-5xgeA:
undetectable
2eilJ-5xgeA:
undetectable
2eilC-5xgeA:
undetectable
2eilJ-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
4 / 7 LYS A 699
PHE A 665
LEU A 661
PHE A 657
None
0.84A 2eimP-5xgeA:
undetectable
2eimW-5xgeA:
undetectable
2eimP-5xgeA:
undetectable
2eimW-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
4 / 6 LEU A 658
GLN A 659
PHE A 660
LEU A 698
None
0.95A 2einP-5xgeA:
undetectable
2einW-5xgeA:
undetectable
2einP-5xgeA:
undetectable
2einW-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G78_A_REAA200_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 12 PHE A 694
LEU A 698
ILE A 675
THR A 614
VAL A 621
None
1.14A 2g78A-5xgeA:
undetectable
2g78A-5xgeA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 12 THR A 682
ALA A 684
LEU A 688
LEU A 723
ILE A 751
None
1.13A 2qxsA-5xgeA:
undetectable
2qxsA-5xgeA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_1
(ESTROGEN RECEPTOR)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 12 THR A 682
ALA A 684
LEU A 688
LEU A 723
ILE A 751
None
1.14A 2qxsB-5xgeA:
undetectable
2qxsB-5xgeA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
4 / 6 LEU A 658
GLN A 659
PHE A 660
LEU A 698
None
1.04A 2zxwP-5xgeA:
undetectable
2zxwW-5xgeA:
undetectable
2zxwP-5xgeA:
undetectable
2zxwW-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
4 / 7 LYS A 699
PHE A 665
LEU A 661
PHE A 657
None
0.81A 3asnP-5xgeA:
undetectable
3asnW-5xgeA:
undetectable
3asnP-5xgeA:
undetectable
3asnW-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
4 / 7 LYS A 699
PHE A 665
LEU A 661
PHE A 657
None
0.78A 3asoP-5xgeA:
undetectable
3asoW-5xgeA:
undetectable
3asoP-5xgeA:
undetectable
3asoW-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXT_A_SAMA397_0
(PROBABLE
N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE
TRM1)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 12 ARG A 531
LEU A 500
ALA A 520
SER A 516
ALA A 407
None
1.25A 3axtA-5xgeA:
undetectable
3axtA-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_0
(UNCHARACTERIZED
PROTEIN RPA2492)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 12 LEU A 313
PRO A 742
GLY A 320
GLY A 341
LEU A 355
None
1.12A 3e23A-5xgeA:
undetectable
3e23A-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_2
(HIV-1 PROTEASE)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
4 / 4 GLY A 442
ASP A 447
GLY A 458
THR A 380
None
1.07A 3k4vC-5xgeA:
undetectable
3k4vC-5xgeA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_2
(PROTEIN S100-A4)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
4 / 6 LEU A 439
ILE A 480
CYH A 494
PHE A 492
None
0.84A 3ko0B-5xgeA:
undetectable
3ko0B-5xgeA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_1
(PROTEIN S100-A4)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
4 / 6 LEU A 439
ILE A 480
CYH A 494
PHE A 492
None
0.91A 3ko0S-5xgeA:
undetectable
3ko0S-5xgeA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_C_BEZC264_0
(CARNITINYL-COA
DEHYDRATASE)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
4 / 6 ALA A 285
ILE A 267
LEU A 293
GLU A 275
None
0.85A 3r9sC-5xgeA:
undetectable
3r9sC-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VXI_A_ASCA502_0
(DYP)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
4 / 5 ALA A 395
ASN A 463
ARG A 401
HIS A 406
None
0.88A 3vxiA-5xgeA:
1.7
3vxiA-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMA_D_ADND604_1
(PYRUVATE KINASE)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
3 / 3 ARG A 398
GLU A 462
ASN A 402
None
0.77A 4imaD-5xgeA:
6.2
4imaD-5xgeA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IP7_D_ADND604_1
(PYRUVATE KINASE
ISOZYMES L)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
3 / 3 ARG A 398
GLU A 462
ASN A 402
None
0.75A 4ip7D-5xgeA:
4.3
4ip7D-5xgeA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IP7_D_ADND604_1
(PYRUVATE KINASE
ISOZYMES L)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
3 / 3 ARG A 401
GLU A 462
ASN A 463
None
0.89A 4ip7D-5xgeA:
4.3
4ip7D-5xgeA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_B_SALB801_1
(PROTEIN POLYBROMO-1)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
4 / 5 LEU A 707
ALA A 691
ASN A 687
ILE A 652
None
1.12A 4y03B-5xgeA:
undetectable
4y03B-5xgeA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
4 / 7 LEU A 658
GLN A 659
PHE A 660
LEU A 698
None
0.98A 5b1bP-5xgeA:
undetectable
5b1bW-5xgeA:
undetectable
5b1bP-5xgeA:
undetectable
5b1bW-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 10 GLY A 755
HIS A 756
HIS A 753
THR A 762
ILE A 751
None
1.43A 5eeuP-5xgeA:
undetectable
5eeuQ-5xgeA:
undetectable
5eeuP-5xgeA:
undetectable
5eeuQ-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 10 GLY A 755
HIS A 756
HIS A 753
THR A 762
ILE A 751
None
1.43A 5eeuR-5xgeA:
undetectable
5eeuS-5xgeA:
undetectable
5eeuR-5xgeA:
undetectable
5eeuS-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 10 GLY A 755
HIS A 756
HIS A 753
THR A 762
ILE A 751
None
1.41A 5eeuS-5xgeA:
undetectable
5eeuT-5xgeA:
undetectable
5eeuS-5xgeA:
undetectable
5eeuT-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 10 GLY A 755
HIS A 756
HIS A 753
THR A 762
ILE A 751
None
1.42A 5eeuU-5xgeA:
undetectable
5eeuV-5xgeA:
undetectable
5eeuU-5xgeA:
undetectable
5eeuV-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 10 GLY A 755
HIS A 756
HIS A 753
THR A 762
ILE A 751
None
1.43A 5eevP-5xgeA:
undetectable
5eevQ-5xgeA:
undetectable
5eevP-5xgeA:
undetectable
5eevQ-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 10 GLY A 755
HIS A 756
HIS A 753
THR A 762
ILE A 751
None
1.41A 5eevS-5xgeA:
undetectable
5eevT-5xgeA:
undetectable
5eevS-5xgeA:
undetectable
5eevT-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 10 GLY A 755
HIS A 756
HIS A 753
THR A 762
ILE A 751
None
1.43A 5eevU-5xgeA:
undetectable
5eevV-5xgeA:
undetectable
5eevU-5xgeA:
undetectable
5eevV-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 10 GLY A 755
HIS A 756
HIS A 753
THR A 762
ILE A 751
None
1.43A 5eewP-5xgeA:
undetectable
5eewQ-5xgeA:
undetectable
5eewP-5xgeA:
undetectable
5eewQ-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 10 GLY A 755
HIS A 756
HIS A 753
THR A 762
ILE A 751
None
1.41A 5eewS-5xgeA:
undetectable
5eewT-5xgeA:
undetectable
5eewS-5xgeA:
undetectable
5eewT-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 10 GLY A 755
HIS A 756
HIS A 753
THR A 762
ILE A 751
None
1.43A 5eexP-5xgeA:
undetectable
5eexQ-5xgeA:
undetectable
5eexP-5xgeA:
undetectable
5eexQ-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 10 GLY A 755
HIS A 756
HIS A 753
THR A 762
ILE A 751
None
1.41A 5eexS-5xgeA:
undetectable
5eexT-5xgeA:
undetectable
5eexS-5xgeA:
undetectable
5eexT-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 10 GLY A 755
HIS A 756
HIS A 753
THR A 762
ILE A 751
None
1.43A 5eeyP-5xgeA:
undetectable
5eeyQ-5xgeA:
undetectable
5eeyP-5xgeA:
undetectable
5eeyQ-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 10 GLY A 755
HIS A 756
HIS A 753
THR A 762
ILE A 751
None
1.41A 5eeyS-5xgeA:
undetectable
5eeyT-5xgeA:
undetectable
5eeyS-5xgeA:
undetectable
5eeyT-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 10 GLY A 755
HIS A 756
HIS A 753
THR A 762
ILE A 751
None
1.43A 5eezP-5xgeA:
undetectable
5eezQ-5xgeA:
undetectable
5eezP-5xgeA:
undetectable
5eezQ-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 10 GLY A 755
HIS A 756
HIS A 753
THR A 762
ILE A 751
None
1.41A 5eezS-5xgeA:
undetectable
5eezT-5xgeA:
undetectable
5eezS-5xgeA:
undetectable
5eezT-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 10 GLY A 755
HIS A 756
HIS A 753
THR A 762
ILE A 751
None
1.42A 5ef0P-5xgeA:
undetectable
5ef0Q-5xgeA:
undetectable
5ef0P-5xgeA:
undetectable
5ef0Q-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 10 GLY A 755
HIS A 756
HIS A 753
THR A 762
ILE A 751
None
1.43A 5ef1P-5xgeA:
undetectable
5ef1Q-5xgeA:
undetectable
5ef1P-5xgeA:
undetectable
5ef1Q-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 10 GLY A 755
HIS A 756
HIS A 753
THR A 762
ILE A 751
None
1.41A 5ef1S-5xgeA:
undetectable
5ef1T-5xgeA:
undetectable
5ef1S-5xgeA:
undetectable
5ef1T-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 10 GLY A 755
HIS A 756
HIS A 753
THR A 762
ILE A 751
None
1.43A 5ef2P-5xgeA:
undetectable
5ef2Q-5xgeA:
undetectable
5ef2P-5xgeA:
undetectable
5ef2Q-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 10 GLY A 755
HIS A 756
HIS A 753
THR A 762
ILE A 751
None
1.41A 5ef2S-5xgeA:
undetectable
5ef2T-5xgeA:
undetectable
5ef2S-5xgeA:
undetectable
5ef2T-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 10 GLY A 755
HIS A 756
HIS A 753
THR A 762
ILE A 751
None
1.43A 5ef3P-5xgeA:
undetectable
5ef3Q-5xgeA:
undetectable
5ef3P-5xgeA:
undetectable
5ef3Q-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 10 GLY A 755
HIS A 756
HIS A 753
THR A 762
ILE A 751
None
1.41A 5ef3S-5xgeA:
undetectable
5ef3T-5xgeA:
undetectable
5ef3S-5xgeA:
undetectable
5ef3T-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
4 / 7 LYS A 699
PHE A 665
LEU A 661
PHE A 657
None
0.79A 5x1fP-5xgeA:
undetectable
5x1fW-5xgeA:
undetectable
5x1fP-5xgeA:
undetectable
5x1fW-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QYA_B_FOZB401_0
(THYMIDYLATE SYNTHASE)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 12 LEU A 476
ILE A 459
LEU A 514
LEU A 500
GLY A 499
None
1.35A 6qyaB-5xgeA:
undetectable
6qyaB-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QYA_D_FOZD401_0
(THYMIDYLATE SYNTHASE)
5xge UNCHARACTERIZED
PROTEIN PA0861

(Pseudomonas
aeruginosa)
5 / 12 LEU A 476
ILE A 459
LEU A 514
LEU A 500
GLY A 499
None
1.35A 6qyaD-5xgeA:
undetectable
6qyaD-5xgeA:
undetectable