SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xgo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AVP_A_MV2A313_1
(PANTOTHENATE KINASE)		 5xgo DNA PROTECTION
DURING STARVATION
PROTEIN,BACTERIOFERR
ITIN
(Escherichia
coli) 		4 / 7 VAL A 114
ASP A 167
LEU A 118
ILE A  60
 None
 1.01A 3avpA-5xgoA:
undetectable		 3avpA-5xgoA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_D_NCAD302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 5xgo DNA PROTECTION
DURING STARVATION
PROTEIN,BACTERIOFERR
ITIN
(Escherichia
coli) 		4 / 7 LEU A  73
ASP A 154
ALA A 151
TYR A 125
 None
 0.86A 3rodD-5xgoA:
undetectable		 3rodD-5xgoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U52_A_CUA515_0
(PHENOL HYDROXYLASE
COMPONENT PHL
PHENOL HYDROXYLASE
COMPONENT PHN)		 5xgo DNA PROTECTION
DURING STARVATION
PROTEIN,BACTERIOFERR
ITIN
(Escherichia
coli) 		3 / 3 HIS A 112
HIS A 117
ILE A 111
 None
 0.73A 3u52A-5xgoA:
5.9
3u52C-5xgoA:
5.2		 3u52A-5xgoA:
undetectable
3u52C-5xgoA:
undetectable