SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xgt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ACA_C_DXCC1475_0 (TRANSLATION ELONGATION FACTOR SELB)	5xgt	SINGLE-STRANDED DNA-BINDING PROTEIN (Staphylococcus aureus)	4 / 8	VAL A 6 SER A 99 GLN A 101 GLY A 72	None	0.62A	4acaC-5xgtA: undetectable	4acaC-5xgtA: 12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ACB_C_DXCC1475_0 (TRANSLATION ELONGATION FACTOR SELB)	5xgt	SINGLE-STRANDED DNA-BINDING PROTEIN (Staphylococcus aureus)	4 / 8	VAL A 6 SER A 99 GLN A 101 GLY A 72	None	0.65A	4acbC-5xgtA: undetectable	4acbC-5xgtA: 12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EOH_A_TEPA402_1 (PYRIDOXAL KINASE)	5xgt	SINGLE-STRANDED DNA-BINDING PROTEIN (Staphylococcus aureus)	4 / 5	SER A 25 THR A 28 VAL A 61 ASP A 59	None	1.06A	4eohA-5xgtA: undetectable	4eohA-5xgtA: 18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6E5Z_A_CCSA106_0 (PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1)	5xgt	SINGLE-STRANDED DNA-BINDING PROTEIN (Staphylococcus aureus)	5 / 10	GLY A 9 ASN A 34 ALA A 32 THR A 12 GLY A 68	None	1.03A	6e5zA-5xgtA: undetectable	6e5zA-5xgtA: 19.79

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4ACA_C_DXCC1475_0","TRANSLATION ELONGATION FACTOR SELB","5xgt","SINGLE-STRANDED DNA-BINDING PROTEIN","Staphylococcus aureus",4,"VAL A   6;SER A  99;GLN A 101;GLY A  72","None","0.62A","4acaC-5xgtA:undetectable","4acaC-5xgtA:12.66"],["4ACB_C_DXCC1475_0","TRANSLATION ELONGATION FACTOR SELB","5xgt","SINGLE-STRANDED DNA-BINDING PROTEIN","Staphylococcus aureus",4,"VAL A   6;SER A  99;GLN A 101;GLY A  72","None","0.65A","4acbC-5xgtA:undetectable","4acbC-5xgtA:12.66"],["4EOH_A_TEPA402_1","PYRIDOXAL KINASE","5xgt","SINGLE-STRANDED DNA-BINDING PROTEIN","Staphylococcus aureus",4,"SER A  25;THR A  28;VAL A  61;ASP A  59","None","1.06A","4eohA-5xgtA:undetectable","4eohA-5xgtA:18.22"],["6E5Z_A_CCSA106_0","PROTEIN\/NUCLEIC ACID DEGLYCASE DJ-1","5xgt","SINGLE-STRANDED DNA-BINDING PROTEIN","Staphylococcus aureus",5,"GLY A   9;ASN A  34;ALA A  32;THR A  12;GLY A  68","None","1.03A","6e5zA-5xgtA:undetectable","6e5zA-5xgtA:19.79"]]