SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xgv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AXW_A_MTXA732_1
(THYMIDYLATE SYNTHASE)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 12 HIS A 319
ILE A 162
ASP A 150
GLY A 148
ALA A 153
 None
 1.11A 1axwA-5xgvA:
undetectable		 1axwA-5xgvA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4Y_A_TPVA501_1
(PROTEIN (HIV-1
PROTEASE))		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 10 LEU A 155
ALA A 276
ASP A 275
GLY A  14
ILE A   7
 FAD  A 501 ( 4.3A)
None
FAD  A 501 (-3.1A)
None
None
 1.01A 1d4yA-5xgvA:
undetectable		 1d4yA-5xgvA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J8U_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 5xgv PYRE3
(Streptomyces
rugosporus) 		4 / 7 VAL A 418
LEU A 436
LEU A 435
ALA A 431
 None
 0.88A 1j8uA-5xgvA:
undetectable		 1j8uA-5xgvA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 11 GLN A 194
HIS A  77
HIS A  74
PHE A 217
PHE A 281
 None
 1.40A 1ydbA-5xgvA:
undetectable		 1ydbA-5xgvA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_1
(PROTEASE)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 11 LEU A 155
ALA A 276
ASP A 275
GLY A  14
ILE A   7
 FAD  A 501 ( 4.3A)
None
FAD  A 501 (-3.1A)
None
None
 1.07A 2o4pA-5xgvA:
undetectable		 2o4pA-5xgvA:
25.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q8H_A_TF4A438_1
([PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 1)		 5xgv PYRE3
(Streptomyces
rugosporus) 		4 / 6 LEU A 104
ILE A 292
ARG A  57
ILE A  59
 None
 0.60A 2q8hA-5xgvA:
undetectable		 2q8hA-5xgvA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA508_0
(CHORISMATE SYNTHASE)		 5xgv PYRE3
(Streptomyces
rugosporus) 		4 / 5 LEU A 272
ASP A 150
ALA A 276
ILE A 270
 None
 0.98A 2qhfA-5xgvA:
undetectable		 2qhfA-5xgvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_B_ADNB601_1
(METHIONYL-TRNA
SYNTHETASE)		 5xgv PYRE3
(Streptomyces
rugosporus) 		6 / 12 ALA A 325
HIS A 278
GLY A 291
GLU A 293
GLY A 372
LEU A 288
 None
None
None
None
None
FAD  A 501 (-3.9A)
 1.38A 2x1lB-5xgvA:
undetectable		 2x1lB-5xgvA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1162_1
(ALLERGEN ARG R 1)		 5xgv PYRE3
(Streptomyces
rugosporus) 		3 / 3 GLU A 101
HIS A  34
GLU A  32
 None
FAD  A 501 (-3.8A)
FAD  A 501 (-2.6A)
 0.77A 2x45B-5xgvA:
undetectable		 2x45B-5xgvA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1162_1
(ALLERGEN ARG R 1)		 5xgv PYRE3
(Streptomyces
rugosporus) 		3 / 3 GLU A 101
HIS A  34
GLU A  32
 None
FAD  A 501 (-3.8A)
FAD  A 501 (-2.6A)
 0.81A 2x45C-5xgvA:
undetectable		 2x45C-5xgvA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_A_CTCA1385_0
(TETX2 PROTEIN)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 10 GLN A  56
ARG A 322
ASN A 297
GLY A 440
GLY A 289
 None
 1.20A 2y6rA-5xgvA:
27.5		 2y6rA-5xgvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_B_CTCB1385_0
(TETX2 PROTEIN)		 5xgv PYRE3
(Streptomyces
rugosporus) 		4 / 8 GLN A  56
ARG A 322
GLY A 440
GLY A 289
 None
 0.83A 2y6rB-5xgvA:
27.4		 2y6rB-5xgvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 12 GLY A  14
GLY A  11
LEU A 104
ASP A 150
VAL A 147
 None
FAD  A 501 (-3.5A)
None
None
None
 1.04A 2zulA-5xgvA:
undetectable		 2zulA-5xgvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 12 GLY A  14
GLY A  11
LEU A 104
ASP A 150
VAL A 147
 None
FAD  A 501 (-3.5A)
None
None
None
 1.04A 3dmhA-5xgvA:
undetectable		 3dmhA-5xgvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_1
(PROTEASE)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 10 LEU A 155
ALA A 276
ASP A 275
GLY A  14
ILE A   7
 FAD  A 501 ( 4.3A)
None
FAD  A 501 (-3.1A)
None
None
 1.14A 3el5A-5xgvA:
undetectable		 3el5A-5xgvA:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_1
(HIV-1 PROTEASE)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 11 LEU A 155
ALA A 276
ASP A 275
GLY A  14
ILE A   7
 FAD  A 501 ( 4.3A)
None
FAD  A 501 (-3.1A)
None
None
 1.05A 3spkA-5xgvA:
undetectable		 3spkA-5xgvA:
25.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_2
(HIV-1 PROTEASE)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 12 LEU A 155
ALA A 276
ASP A 275
GLY A  14
ILE A   7
 FAD  A 501 ( 4.3A)
None
FAD  A 501 (-3.1A)
None
None
 0.99A 3spkB-5xgvA:
undetectable		 3spkB-5xgvA:
25.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_1
(POL POLYPROTEIN)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 9 LEU A 155
ALA A 276
ASP A 275
GLY A  14
ILE A   7
 FAD  A 501 ( 4.3A)
None
FAD  A 501 (-3.1A)
None
None
 0.95A 3u7sA-5xgvA:
undetectable		 3u7sA-5xgvA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_1
(POL POLYPROTEIN)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 9 LEU A 155
ALA A 276
ASP A 275
GLY A  14
ILE A   7
 FAD  A 501 ( 4.3A)
None
FAD  A 501 (-3.1A)
None
None
 0.95A 3u7sA-5xgvA:
undetectable		 3u7sA-5xgvA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_B_MIYB2001_1
(TETX2 PROTEIN)		 5xgv PYRE3
(Streptomyces
rugosporus) 		4 / 8 GLN A  56
ARG A 322
GLY A 440
GLY A 289
 None
 0.73A 3v3nB-5xgvA:
27.0		 3v3nB-5xgvA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)		 5xgv PYRE3
(Streptomyces
rugosporus) 		4 / 8 GLN A  56
ARG A 322
GLY A 440
GLY A 289
 None
 0.74A 3v3nC-5xgvA:
27.1		 3v3nC-5xgvA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 12 GLN A  56
ARG A 322
ASN A 297
GLY A 440
GLY A 289
 None
 1.26A 3v3oA-5xgvA:
27.0		 3v3oA-5xgvA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_B_T1CB405_1
(TETX2 PROTEIN)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 12 GLN A  56
ARG A 322
ASN A 297
GLY A 440
GLY A 289
 None
 1.28A 3v3oB-5xgvA:
27.2		 3v3oB-5xgvA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_A_T1CA392_1
(TETX2 PROTEIN)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 11 GLN A  56
ARG A 322
ASN A 297
GLY A 440
GLY A 289
 None
 1.33A 4a6nA-5xgvA:
26.8		 4a6nA-5xgvA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_B_T1CB392_1
(TETX2 PROTEIN)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 11 GLN A  56
ARG A 322
ASN A 297
GLY A 440
GLY A 289
 None
 1.32A 4a6nB-5xgvA:
26.9		 4a6nB-5xgvA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_C_T1CC392_1
(TETX2 PROTEIN)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 11 GLN A  56
ARG A 322
ASN A 297
GLY A 440
GLY A 289
 None
 1.34A 4a6nC-5xgvA:
26.9		 4a6nC-5xgvA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_A_MIYA391_1
(TETX2 PROTEIN)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 10 GLN A  56
ARG A 322
ASN A 297
GLY A 440
GLY A 289
 None
 1.17A 4a99A-5xgvA:
27.1		 4a99A-5xgvA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_B_MIYB391_1
(TETX2 PROTEIN)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 11 GLN A  56
ARG A 322
ASN A 297
GLY A 440
GLY A 289
 None
 1.15A 4a99B-5xgvA:
27.4		 4a99B-5xgvA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_C_MIYC391_1
(TETX2 PROTEIN)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 11 GLN A  56
ARG A 322
ASN A 297
GLY A 440
GLY A 289
 None
 1.17A 4a99C-5xgvA:
27.3		 4a99C-5xgvA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD391_1
(TETX2 PROTEIN)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 11 GLN A  56
ARG A 322
ASN A 297
GLY A 440
GLY A 289
 None
 1.15A 4a99D-5xgvA:
27.3		 4a99D-5xgvA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_0
(METHYLTRANSFERASE
NSUN4)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 12 GLY A  43
GLY A  44
LEU A 174
SER A 253
GLY A 215
 FAD  A 501 ( 3.9A)
None
None
None
None
 1.04A 4fp9A-5xgvA:
undetectable		 4fp9A-5xgvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_0
(METHYLTRANSFERASE
NSUN4)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 12 GLY A  43
GLY A  44
LEU A 174
SER A 253
GLY A 215
 FAD  A 501 ( 3.9A)
None
None
None
None
 1.04A 4fp9C-5xgvA:
2.1		 4fp9C-5xgvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_0
(METHYLTRANSFERASE
NSUN4)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 12 GLY A  43
GLY A  44
LEU A 174
SER A 253
GLY A 215
 FAD  A 501 ( 3.9A)
None
None
None
None
 1.03A 4fp9D-5xgvA:
undetectable		 4fp9D-5xgvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_0
(METHYLTRANSFERASE
NSUN4)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 12 GLY A  43
GLY A  44
LEU A 174
SER A 253
GLY A 215
 FAD  A 501 ( 3.9A)
None
None
None
None
 1.04A 4fp9F-5xgvA:
undetectable		 4fp9F-5xgvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_0
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 12 GLY A  43
GLY A  44
LEU A 174
SER A 253
GLY A 215
 FAD  A 501 ( 3.9A)
None
None
None
None
 1.07A 4fzvA-5xgvA:
undetectable		 4fzvA-5xgvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 12 LEU A  15
GLY A  10
VAL A  29
ARG A 109
VAL A 156
 None
FAD  A 501 ( 4.9A)
None
None
None
 1.32A 4okwA-5xgvA:
undetectable		 4okwA-5xgvA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_1
(ANDROGEN RECEPTOR)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 12 LEU A  15
GLY A  10
VAL A  29
ARG A 109
VAL A 156
 None
FAD  A 501 ( 4.9A)
None
None
None
 1.36A 4okxA-5xgvA:
undetectable		 4okxA-5xgvA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_A_STRA601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 5xgv PYRE3
(Streptomyces
rugosporus) 		4 / 6 ALA A 262
GLY A 274
ILE A 162
VAL A 147
 None
FAD  A 501 (-3.5A)
None
None
 0.78A 4r21A-5xgvA:
undetectable		 4r21A-5xgvA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_B_STRB601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 9 ALA A 262
GLY A 274
ALA A 276
ILE A 162
VAL A 147
 None
FAD  A 501 (-3.5A)
None
None
None
 1.04A 4r21B-5xgvA:
undetectable		 4r21B-5xgvA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 12 GLY A 284
ILE A  46
GLY A  43
GLY A 191
PHE A  70
 None
None
FAD  A 501 ( 3.9A)
None
None
 1.10A 5d4uB-5xgvA:
undetectable		 5d4uB-5xgvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EVY_X_SALX502_1
(SALICYLATE
HYDROXYLASE)		 5xgv PYRE3
(Streptomyces
rugosporus) 		4 / 5 SER A 332
GLN A 336
LEU A 366
PHE A  75
 None
 1.29A 5evyX-5xgvA:
25.9		 5evyX-5xgvA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_2
(PROTEASE E35D-APV)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 9 LEU A 155
ALA A 276
ASP A 275
GLY A  14
ILE A   7
 FAD  A 501 ( 4.3A)
None
FAD  A 501 (-3.1A)
None
None
 1.05A 5kr0B-5xgvA:
undetectable		 5kr0B-5xgvA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M24_A_9CRA501_1
(RETINOIC ACID
RECEPTOR GAMMA)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 12 ALA A  76
LEU A 283
SER A 332
PHE A 217
GLY A 215
 None
 1.00A 5m24A-5xgvA:
undetectable		 5m24A-5xgvA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7P_A_SAMA501_0
(OXAC)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 12 ALA A 273
GLY A 274
LEU A  17
LEU A 302
ARG A 157
 None
FAD  A 501 (-3.5A)
None
None
None
 1.19A 5w7pA-5xgvA:
undetectable		 5w7pA-5xgvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_1
(PROTEIN CYP51)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 12 ALA A  45
TYR A 265
ALA A 324
ALA A 327
LEU A 280
 None
 1.23A 6aycA-5xgvA:
undetectable		 6aycA-5xgvA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_B_SAMB901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 5xgv PYRE3
(Streptomyces
rugosporus) 		5 / 12 PHE A  54
LEU A 396
GLY A 440
VAL A  13
ARG A 377
 None
None
None
FAD  A 501 (-3.7A)
None
 1.45A 6bxnB-5xgvA:
2.4		 6bxnB-5xgvA:
undetectable