SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xhb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_C_RAPC999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 5xhb NISIN IMMUNITY
PROTEIN
(Lactococcus
lactis) 		5 / 8 GLU A 171
SER A 219
GLY A 222
THR A 241
TYR A 152
 None
 1.31A 5flcB-5xhbA:
undetectable		 5flcB-5xhbA:
5.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_G_RAPG999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 5xhb NISIN IMMUNITY
PROTEIN
(Lactococcus
lactis) 		5 / 8 GLU A 171
SER A 219
GLY A 222
THR A 241
TYR A 152
 None
 1.30A 5flcF-5xhbA:
undetectable		 5flcF-5xhbA:
5.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB306_0
(WELO5)		 5xhb NISIN IMMUNITY
PROTEIN
(Lactococcus
lactis) 		3 / 3 GLU A  51
ARG A 108
TYR A 110
 None
 0.65A 5trqB-5xhbA:
undetectable		 5trqB-5xhbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		 5xhb NISIN IMMUNITY
PROTEIN
(Lactococcus
lactis) 		4 / 5 PHE A  38
VAL A  70
MET A 103
VAL A  28
 None
 1.21A 6ekzA-5xhbA:
undetectable		 6ekzA-5xhbA:
18.82