SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xhm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5xhm FERRITIN, MIDDLE
SUBUNIT
(Rana
catesbeiana) 		5 / 12 LEU A 116
LEU A 113
LEU A 110
ALA A 109
LEU A  22
 None
 0.69A 1s9pC-5xhmA:
undetectable		 1s9pC-5xhmA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BA0_A_HAEA477_1
(MACROPHAGE
METALLOELASTASE)		 5xhm FERRITIN, MIDDLE
SUBUNIT
(Rana
catesbeiana) 		3 / 3 HIS A  56
GLU A  57
HIS A  54
 None
MG  A 201 (-2.6A)
None
 0.82A 3ba0A-5xhmA:
undetectable		 3ba0A-5xhmA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWM_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 5xhm FERRITIN, MIDDLE
SUBUNIT
(Rana
catesbeiana) 		3 / 3 SER A  32
GLU A  85
ASP A  87
 None
None
CL  A 213 (-4.9A)
 0.86A 3bwmA-5xhmA:
undetectable		 3bwmA-5xhmA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 5xhm FERRITIN, MIDDLE
SUBUNIT
(Rana
catesbeiana) 		3 / 3 SER A  32
GLU A  85
ASP A  87
 None
None
CL  A 213 (-4.9A)
 0.83A 4xudA-5xhmA:
undetectable		 4xudA-5xhmA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_A_ASCA1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 5xhm FERRITIN, MIDDLE
SUBUNIT
(Rana
catesbeiana) 		4 / 6 HIS A 114
TYR A  68
ARG A  72
HIS A 124
 None
 1.40A 5kkzA-5xhmA:
2.2
5kkzG-5xhmA:
undetectable		 5kkzA-5xhmA:
14.13
5kkzG-5xhmA:
21.63