SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xhz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5xhz SH3
DOMAIN-CONTAINING
KINASE-BINDING
PROTEIN 1
(Mus
musculus) 		4 / 8 GLU A 136
ASP A 133
ILE A 135
ILE A 162
 None
 0.90A 1p7lD-5xhzA:
undetectable		 1p7lD-5xhzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5xhz SH3
DOMAIN-CONTAINING
KINASE-BINDING
PROTEIN 1
(Mus
musculus) 		4 / 8 GLU A 136
ASP A 133
ILE A 135
ILE A 162
 None
 0.89A 1p7lC-5xhzA:
undetectable		 1p7lC-5xhzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5xhz SH3
DOMAIN-CONTAINING
KINASE-BINDING
PROTEIN 1
(Mus
musculus) 		4 / 8 GLU A 136
ASP A 133
ILE A 135
ILE A 162
 None
 0.90A 1rg9B-5xhzA:
undetectable		 1rg9B-5xhzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5xhz SH3
DOMAIN-CONTAINING
KINASE-BINDING
PROTEIN 1
(Mus
musculus) 		4 / 8 GLU A 136
ASP A 133
ILE A 135
ILE A 162
 None
 0.89A 1rg9A-5xhzA:
undetectable		 1rg9A-5xhzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5xhz SH3
DOMAIN-CONTAINING
KINASE-BINDING
PROTEIN 1
(Mus
musculus) 		4 / 8 GLU A 136
ASP A 133
ILE A 135
ILE A 162
 None
 0.90A 1rg9D-5xhzA:
undetectable		 1rg9D-5xhzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5xhz SH3
DOMAIN-CONTAINING
KINASE-BINDING
PROTEIN 1
(Mus
musculus) 		4 / 8 GLU A 136
ASP A 133
ILE A 135
ILE A 162
 None
 0.88A 1rg9C-5xhzA:
undetectable		 1rg9C-5xhzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5xhz SH3
DOMAIN-CONTAINING
KINASE-BINDING
PROTEIN 1
(Mus
musculus) 		4 / 8 GLU A 136
ASP A 133
ILE A 135
ILE A 162
 None
 0.90A 4ndnB-5xhzA:
undetectable		 4ndnB-5xhzA:
undetectable