SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xjq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A27_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 5xjq SMALL NUCLEAR
RIBONUCLEOPROTEIN SM
D1
(Homo
sapiens) 		5 / 12 VAL A  15
GLY A  27
LEU A  40
VAL A  32
PHE A  68
 None
 1.38A 1a27A-5xjqA:
undetectable		 1a27A-5xjqA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_A_REAA501_1
(RETINOIC ACID
RECEPTOR BETA)		 5xjq GEM-ASSOCIATED
PROTEIN 2
(Homo
sapiens) 		5 / 11 PHE 2 207
LEU 2 262
ILE 2 263
PHE 2 202
SER 2 199
 None
 1.03A 4dm8A-5xjq2:
undetectable		 4dm8A-5xjq2:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5xjq GEM-ASSOCIATED
PROTEIN 2
(Homo
sapiens) 		4 / 6 ASN 2 200
GLU 2 204
GLU 2 141
GLU 2 142
 None
 1.23A 4mi4A-5xjq2:
undetectable		 4mi4A-5xjq2:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5xjq GEM-ASSOCIATED
PROTEIN 2
(Homo
sapiens) 		4 / 7 ASN 2 200
GLU 2 204
GLU 2 141
GLU 2 142
 None
 1.24A 4mi4A-5xjq2:
undetectable
4mi4C-5xjq2:
undetectable		 4mi4A-5xjq2:
16.75
4mi4C-5xjq2:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5xjq GEM-ASSOCIATED
PROTEIN 2
(Homo
sapiens) 		4 / 7 ASN 2 200
GLU 2 204
GLU 2 141
GLU 2 142
 None
 1.36A 4mj8C-5xjq2:
undetectable		 4mj8C-5xjq2:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_B_REAB503_1
(RETINOIC ACID
RECEPTOR BETA)		 5xjq GEM-ASSOCIATED
PROTEIN 2
(Homo
sapiens) 		5 / 12 CYH 2 241
LEU 2 233
LEU 2 237
ILE 2 234
LEU 2 222
 None
 1.45A 5uanB-5xjq2:
undetectable		 5uanB-5xjq2:
9.57